Chapter 1 Flashcards
(22 cards)
gap junctions
allow for cytoplasmic continuity and direct transfer of electrical and chemical signals between cells and the nervous systems
nerve cells
specialize for electrical signaling over long distance
glia cells
support signaling function of nerve cells
do NOT generate electrical signals
essentially for repairing the nervous system
three different types: astrocytes, oligodendrocytes, schwann cells
mitochondria
can be found largely concentrated at the synapses of neurons
protein synthetic organelles
are kept out of axons and dendrites
dendrites
primary target for synaptic input from axon terminals of other neurons
have a high concentration of ribosomes and skeletal proteins
degree ofconvergence
number of inputs a single neuron reflects
divergency
number of targets supplied by one neuron
synaptic cleft
a site of extracellular proteins that have functions including diffusion, binding, and degradation of molecules
ex: NTs
synaptic vesicles
secretory organelles located in the pre synaptic terminal of chemical synapses and are filled with NT and other neuro molecules
astrocytes
maintain the correct chemical environment for neural signaling, like the formation of the BBB
can be found in the CNS (brain and spinal cord
oligodendrocytes
also restricted to the CNS
they are responsible for laying down myelin around some axons
can self generate as a response of injury or disease
schwann cells
found in the peripheral nervous system
are the cells that provide the myelin
microglia
they remove any cellular debris due to injury aka take out the trash from our cells
afferent neurons
nerve cells that carry info from other areas of the body towards the brain or spinal cord
efferent neurons
carry info from the brain or spinal cord away to other areas of the brain
extracellular recording
an electrode is placed near the nerve cells we want to study in order to detect its activity
useful for detecting temporal patterns of AP due to stimulation or behavioral events
intracellular recording
the electrode is placed inside the cell we want to study in order to detect its activity
detects smaller changes in electrical potential that trigger APs
calcium imaging
records the transient changes in intracellular concentration of calcium ions that are associated with AP firing
calcium channels
establish currents that lead to voltage changes in neurons
is an important 2nd messenger
optogenetics
modified and are expressed in living neurons. they can response to light and therefore light can be used to control nerve cells activity and behaviors of organisms such as mice
receptive field
neurons’ region in sensory space within which a stimulus can generate an AP as a response