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Flashcards in Chapter 1 Deck (14):
1

Aluminum, fluoride, iron and gold are what type of compound

Inorganic compound

2

What is the purpose of the FDA?

Regulates the development of and sale of drugs

3

For every 100,000 potential drugs, how many become actual drugs?

5

4

Preclinical trials-
Phase 1-
Phase 2-
Phase 3
Phase 4-

Preclinical trials- animals
Phase 1- human volunteers, men
Phase 2- actually patients that have a the disease
Phase 3- wide scale use with patients that have the disease
Phase 4- continual evaluation of the drug and therapeutic effects

5

What is used for insulin production

Escherichia coli

6

What is the purpose of the controlled substance act of 1970
(2 reasons)

Ranking the abuse potential

7

Function of the FDA?

Regulates the development and sale of the drugs

8

Category A
Category B
Category C
Category D
Category X

Category A - no risk to fetus in first trimester
Category B - no fetus risk with animals,no studies with pregnant women
Category C - adverse effects in animals fetuses
Category D - evidence of human fetal risk
Category X - never used in pregnancy

9

Schedule 1

Street drugs. no medical use

10

Schedule 2

Highs abuse potential, narcotics, amphetamines, barbiturates

11

Schedule 3

Less abuse potential than schedule 2,
NOn barbiturate, Nonamphetamines

12

Schedule 4

Limited dependence liability

13

Schedule 5

Small amounts of narcotics, purchased without a prescription must be 18 years old

14

Orphan drugs

Not financially available, not adopted by drug companies
Limited market or narrow margin of safety