Flashcards in Chapter 1 - Diagnostic Testing Deck (12):
List three criteria for a screening test.
Criteria for screening test: ↑sensitivity and prevalence; cost-effective; treatable
What is the overall best screening test for cancer?
Cervical Pap: overall best screening test for cancer
Give an example of a test used to confirm a disease.
Confirm disease: serum troponins to diagnose AMI
Give three examples of monitoring disease status.
Monitor disease: HbA1c, INR, pulse oximeter
What are the terms for test results for people with a specific disease?
Test results in people with disease: TP and FN
What are the terms for test results for people without disease?
Test results in people without disease: TN and FP
What is the formula to calculate sensitivity? What is sensitivity?
Sensitivity = TP ÷ (TP + FN); “positivity” in disease
What are two features of a test with 100% sensitivity?
Test with 100% sensitivity: normal result TN; positive result TP or FP
What is the formula for calculating specificity? What is specificity?
Specificity = TN ÷ (TN + FP); “negativity” in health
What are two features of a test with 100% specificity?
Test with 100% specificity: positive test TP; negative test TN or FN
What is the usefulness of a test with 100% sensitivity?
Usefulness of test with 100% sensitivity: exclude disease when test returns normal