Chapter 10 Flashcards
Disease and Immunity
What is a Pathogen?
A pathogen is a disease causing organism.
What is a transmissable disease?
It is a disease in which a pathogen passes from one host to another.
How are Pathogens transmitted?
By Direct contact - Blood and body fluids
By Indirect contact- Contaminated surfaces, food, water, air.
What are the Bodys defences?
- Skin: Physical barrier prevents pathogens from entering the body.
- Hairs in nose: Nose hairs act as a natural filter, trapping dust and pathogens from entering the lungs.
- Mucus: Sticky substance traps pathogens before entering lungs.
- Stomach acid: HCL kills pathogens consumed with food.
- WBCs: Carry out Phagocytosis + Antibody production.
How can we control spread of disease?
- Good water supply (diseases caused otherwise are cholera, Diarrhoea, dysentery, typhoid)
- Hygienic food preparation
- Personal hygiene
- Waste disposal
- Sewage treatment
What is Active immunity?
It is defense against a pathogen by antibody production.
- It is gained after infection or by Vaccination
- Lymphocytes also produce MEMORY CELLS that remain in blood even after an infection is over.
- These can quickly produce original antibodies if the same pathogen came again.
- This is long-term immunity.
What are Antigens?
Antigens are a unique marker shape on the surface of membranes of Pathogens.
Antigens have a specific shape.
What is the function of Antibodies on Antigens?
Lymphocytes produce proteins called Antibodies which are complementary to the Antigen of Pathogens.
- Antibodies bind to Antigens of Pathogens, destroying them or marking them for Phagocytes.
What is Vaccination?
It is a way of protecting the body against harmful diseases.
What is the process of Vaccination?
- Weakened pathogens or antigens are put into the body.
- The antigens stimulate immune response from lymphocytes which produce Antibodies.
- Antibodies produce memory cells which give long-term immunity.
What is a Vaccine and its types?
Its what is injected/swallowed:
- A harmless form of micro-organism ex: BCG inoculation/Sabin Oral vaccine
- The killed micro-organism ex: Salk anti-polio vaccine
- A toxoid: The inactivated toxin produced by bacteria.
What is Passive immunity?
Its short-term defense against pathogens by Antibodies obtained from another individual:
- From mothers blood
- Breast milk
There is NO FORMATION OF MEMORY CELLS.
What is Cholera?
It is a disease caused by bacterium transmitted in contaminated water.
- It causes Diarrhoea.
What is the process of Cholera?
- Cholera is caused when bacteria invade the wall of the small intenstine.
- Here they rapidly reproduce and produce a toxin.
- The toxin causes cells in the intestine to secrete Chloride ions
- This causes the water potential in small intestine to decrease
- As a result, water from cells in intestine lining move into the small intestine by Osmosis.
- Large amounts of water is lost from the body; causing Dehydration