Chapter 10 Flashcards

Disease and Immunity

1
Q

What is a Pathogen?

A

A pathogen is a disease causing organism.

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2
Q

What is a transmissable disease?

A

It is a disease in which a pathogen passes from one host to another.

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3
Q

How are Pathogens transmitted?

A

By Direct contact - Blood and body fluids
By Indirect contact- Contaminated surfaces, food, water, air.

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4
Q

What are the Bodys defences?

A
  • Skin: Physical barrier prevents pathogens from entering the body.
  • Hairs in nose: Nose hairs act as a natural filter, trapping dust and pathogens from entering the lungs.
  • Mucus: Sticky substance traps pathogens before entering lungs.
  • Stomach acid: HCL kills pathogens consumed with food.
  • WBCs: Carry out Phagocytosis + Antibody production.
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5
Q

How can we control spread of disease?

A
  • Good water supply (diseases caused otherwise are cholera, Diarrhoea, dysentery, typhoid)
  • Hygienic food preparation
  • Personal hygiene
  • Waste disposal
  • Sewage treatment
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6
Q

What is Active immunity?

A

It is defense against a pathogen by antibody production.
- It is gained after infection or by Vaccination
- Lymphocytes also produce MEMORY CELLS that remain in blood even after an infection is over.
- These can quickly produce original antibodies if the same pathogen came again.
- This is long-term immunity.

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7
Q

What are Antigens?

A

Antigens are a unique marker shape on the surface of membranes of Pathogens.
Antigens have a specific shape.

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8
Q

What is the function of Antibodies on Antigens?

A

Lymphocytes produce proteins called Antibodies which are complementary to the Antigen of Pathogens.
- Antibodies bind to Antigens of Pathogens, destroying them or marking them for Phagocytes.

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9
Q

What is Vaccination?

A

It is a way of protecting the body against harmful diseases.

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10
Q

What is the process of Vaccination?

A
  • Weakened pathogens or antigens are put into the body.
  • The antigens stimulate immune response from lymphocytes which produce Antibodies.
  • Antibodies produce memory cells which give long-term immunity.
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11
Q

What is a Vaccine and its types?

A

Its what is injected/swallowed:
- A harmless form of micro-organism ex: BCG inoculation/Sabin Oral vaccine
- The killed micro-organism ex: Salk anti-polio vaccine
- A toxoid: The inactivated toxin produced by bacteria.

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12
Q

What is Passive immunity?

A

Its short-term defense against pathogens by Antibodies obtained from another individual:
- From mothers blood
- Breast milk
There is NO FORMATION OF MEMORY CELLS.

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13
Q

What is Cholera?

A

It is a disease caused by bacterium transmitted in contaminated water.
- It causes Diarrhoea.

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14
Q

What is the process of Cholera?

A
  • Cholera is caused when bacteria invade the wall of the small intenstine.
  • Here they rapidly reproduce and produce a toxin.
  • The toxin causes cells in the intestine to secrete Chloride ions
  • This causes the water potential in small intestine to decrease
  • As a result, water from cells in intestine lining move into the small intestine by Osmosis.
  • Large amounts of water is lost from the body; causing Dehydration
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