Chapter 10 Highlights Flashcards

1
Q

Myocyte

A

Muscle cell

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2
Q

Sarcoplasm

A

Myocyte cytoplasm

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3
Q

Sarcolemma

A

Myocyte plasma membrane

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4
Q

Sarcoplasmic Reticulum (SR)

A
  • Modified endoplasmic reticulum
  • Forms web-like network surrounding myofibrils
  • Varies in structure in three types of muscle tissue
  • Stores and released calcium ions
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5
Q

Myofibrils

A
  • Bundles of specialized proteins

- Allow for contraction

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6
Q

Composition of skeletal muscle tissue

A

Fibers and endomysium

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7
Q

Skeletal muscle (organization)

A
  • Surrounded by epimysium

- Contains muscle fascicles

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8
Q

Muscle fascicles (organization)

A
  • Surrounded by perimysium

- Contains muscle fibers

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9
Q

Muscle fibers (organization)

A
  • Surrounded by endomysium

- Contains myofibrils

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10
Q

Myofibrils (organization)

A
  • Surrounded by sarcoplasmic reticulum

- Contains sarcomeres (Z line to Z line)

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11
Q

Sarcomere

A
  • Contains thick and thin filaments
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12
Q

Transverse tubules

A
  • Deep inward extensions of sarcolemma
  • Surrounds each myofibril
  • Continuous with exterior of cell
  • Filled with extracellular fluid
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13
Q

Terminal cisternae

A
  • Enlarged sections of SR

- Flank each t-tubule

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14
Q

Triad

A

Two terminal cisternae plus corresponding t-tubule

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15
Q

Thick filaments

A
  • Myosin

- Binds to actin

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16
Q

Thin filaments

A

Actin, tropomyosin, and troponin

17
Q

Elastic filaments

A
  • Single massive, spring-like structural protein (titin)
  • Stabilizes myofibril structure
  • Resists excessive stretching
18
Q

Tropomyosin

A
  • Long, rope-like regulatory protein

- Twists around actin, covering up active sites

19
Q

Troponin

A
  • Small globular regulatory protein
  • Holds tropomyosin in place
  • Assists with turning contractions on and off
20
Q

I band

A

Only thin filaments

21
Q

Z disc

A
  • In middle of I band

- Structural proteins that anchor thin filaments in place and to one another

22
Q

A band

A
  • Zone of overlap
  • Both thick and thin filaments
  • Generate tension during contraction
23
Q

H zone

A

Middle of A band where only thick filaments exist

24
Q

M line

A
  • Dark line in the middle of A band
  • Structural proteins hold thick filaments in place
  • Serve as anchoring point for elastic filaments
25
Steps of sliding filament cycle
- Action potential reaches the SR and calcium is released - Calcium binds to troponin - Troponin moves, moving tropomyosin and exposing actin active site - Myosin hinges, myosin head forms cross bridge with actin and moves actin towards the M line, eliminating H zone and I band - ATP allows release of cross bridge and leaves myosin reenergized - Calcium (80%) is pumped back to the SR
26
What happens to I band during contraction?
Narrows
27
What happens to H zone during contraction?
Narrows
28
What happens to A band during contraction?
Unchanged
29
What does myosin attach to?
Actin
30
What does myosin do to the myofilaments?
Myosin pulls thin filaments toward M line
31
What is rigor mortis?
Progressive stiffening of skeletal muscles
32
When does rigor mortis occur?
3-4 hours after death
33
Why does rigor mortis occur?
- Pumps that drive Ca back into SR have no more ATP to fuel activity - Ca remains in cytosol, binds to troponin and initiates contraction
34
Why does the stiffness of rigor mortis remain?
Muscles cannot relax without ATP, so myosin heads cannot detach from actin
35
How long does rigor mortis last?
- Contraction remains until myofilament proteins degenerate | - About 48-72 hours after death