Chapter 11 Flashcards Preview

BMB > Chapter 11 > Flashcards

Flashcards in Chapter 11 Deck (9)
Loading flashcards...

Define passive transport

There is no energy input required

exemplified by simple diffusions and facilitated diffusion

uses concentration gradient; molecules move across a bilayer based on gradients


Define Active Transport

uses energy to transfer molecules against a concentration gradient


Facilitated Diffusion

uses channel proteins to move large or charged molecules down their concentration gradient

ex) chemically gated Na+ channel found in muscle cell plasma membranes


Simple Diffusion

involves the propulsion of each solute by random molecular motion from an area of high concentration to an area of low concentration


What allows the uptake of glucose from the blood to ultimately lower blood sugar?


causes change within cells that are response/sensitive to insulin


What are the two forms of active transport and define them?

Primary Active Transport
- transmembrane ATP-hydrolizing enzymes provide the energy to drive the transport of ions or molecules
- NaK ATPase (sodium potassium pump)

Secondary Active Transport
- concentration gradients formed by primary active transport tare used to move their substances across the membrane
- ATP-ADP translocase - movement of ATP out of inner membrane space and ADP into the mitochondrial matrix to be used to make ATP


Cystic Fibroses

autosomal recessive genetic disorder (from Mom and Dad)

greatly effects the lungs and digestive tract


CFTR Protein

- chloride transporter found at the plasma membrane of epithelial cells
- in normal cells, allows the release of Cl- from the cell

-when blocked it causes very thick and dry mucus layer


Effects of thick mucus secretions in CF

in lungs - prevent cilia on surface of cells from clearing bacteria and also makes it difficult to breathe

in pancreas - block passageways so digestive enzymes cannot get to the intestine - can't absorb nutrients