Chapter 16 + 17 Flashcards
(29 cards)
Hexokinase
Phosphorylates glucose
Phosphoglucose isomer add
Converts glucose 6 phosphate into fructose 6 phosphate
Phosphofructokinase
Forms fructose 1 6 bisphosphate
Aldolase
Cleaves fructose 1 6 bisphosphate
Triode phosphate isomerase
Catalyze the inter conversion of 3 carbon isomers
Goyceraldehyde 3 phosphate dehydrogenase
Generates the first high phosphoryl transfer that is not ATP
Phosphoglycerate
Generates first molecule ATP
Phosphoglycerate mutate
Converts 3 phosphoglycerate into 2 phosphoglycerate
Enolase
Generate second high phosphoryl transfer potential not ATP
Pyruvate kinase
Generates second molecule ATP
In fermentation what is donor and acceptor
Glyceraldehyde 3 phosphate is donor
Pyruvate in lactic and acetylaldehyde in alcohol are acceptors
Why is glucokimase important
When max ATP hexokinase inhibited and want to still make and store
Why do we need niacin
Make NAD+
Why can’t we reverse glycolysis
Some reactions are far to exergonic
What is fate of puruvate
Ethanol lactic acid
H20 CO2
What is effect of lactic acid buildup
Lower pH highly acidic
What does fructose 2 6 bisphosphate do in terms of allosteric
Stabilizes R state
Why can’t we just run glycolysis in reverse
Highly endergonic steps
What generates pyruvate
Protein
Lactate
Glycerol
Pyruvate carboxylase
Generates oxaloacetate
Acetyl coA
Required for pyruvate carboxylase activity
Phosphoenolpyruvate carboxykinase
Generate high phosphoryl transfer potential compound
Glycerol
Readily converted to DHAP
Fructose 1 6 bisphosphotase
Gluconeogenic counterpart of PFK