Chapter 18 Part I: Endocrine System Flashcards
Introduction to the Endocrine System
• Glands release hormones.
• Hormones regulate the many and varied functions of an organism.
• Hormones bind to receptors.
• Receptors are recognition sites in the various target tissues on which hormones act.
Introduction to the Endocrine System (Cont’d)
• ENDOCRINE glands-
Secrete their hormones directly into the bloodstream.
• EXOCRINE glands-
Send chemical substances (tears, sweat, milk, saliva) via ducts to the outside of the body.
Endocrine Glands
• Thyroid gland
• Parathyroid glands (four glands)
• Adrenal glands (one pair)
• Pancreas (islets of Langerhans)
• Pituitary gland
• Ovaries (one pair)
• Testes (one pair)
• Pineal gland
• Thymus gland
Endocrine Tissue (Apart from Major Glands): Location, Secretion, and Action: Body cells
Secretion:
- Prostagladins
Action:
- Aggregation of platelets
- Contract uterus
- Lower acid secretion in stomach
- Lower blood pressure
Endocrine Tissue (Apart from Major Glands): Location, Secretion, and Action: Gastrointestinal tract
Secretion:
- Cholecystokinin
- Gastrin
- Secretin
Action:
- Contracts gallbladder
- Stimulates gastric secretion
- Stimulates pancreatic enzymes
Endocrine Tissue (Apart from Major Glands): Location, Secretion, and Action: Kidney
Secretion:
- Erythropoietin
Action:
- Stimulates erythrocyte production
Endocrine Tissue (Apart from Major Glands): Location, Secretion, and Action: Pineal gland
Secretion:
- Melatonin
Action:
- Induces sleep and affects mood
Endocrine Tissue (Apart from Major Glands): Location, Secretion, and Action: Placenta
Secretion:
- Human chorionic gonadotropin
Action:
- Sustains pregnancy
Endocrine Tissue (Apart from Major Glands): Location, Secretion, and Action: Skin
Secretion:
- Vitamin D
Action:
- Affects absorption of calcium
Endocrine Tissue (Apart from Major Glands): Location, Secretion, and Action: Thymus
Secretion:
-Thymosin
Action:
- Affects immune response
Thyroid Gland Continents Top to Bottom:
- Thyroid cartilage
- Thyroid gland
- Isthmus
- Trachea
Thyroid Function
• There are two hormones:
- Thyroxine or tetraiodothyronine (T4)
- Triiodothyronine (T3)
• Thyroid hormones aid cells in their uptake of oxygen and regulate metabolic rate.
• Calcitonin: stimulates calcium to leave the blood and enter the bone.
Thyroid Gland: Hormones and Actions
- T3 (triiodothyronine): increases metabolism
- T4 (thyroxine): increases metabolism
- Calcitonin: decreases blood calcium
Parathyroid Gland Continents Top to Bottom:
- Epiglottis
- Pharynx
- Thyroid gland
- Parathyroid glands
- Esophagus
- Trachea
Parathyroid Glands
Secrete parathyroid hormone (PTH) which increase blood calcium.
Parathyroid Function
Parathyroid hormone (PTH): causes calcium to mobilize from bones into the bloodstream.
• Calcitonin vs PTH: range of blood calcium level tightly regulated!!
Calcium
• Calcitonin vs PTH: range of blood calcium level tightly regulated!!
• Calcium: hypercalcemia or hypocalcemia.
- Stronger bones and teeth
- Muscle contraction
- Nerve impulse transmission
- Blood clotting
- Release of hormones
Adrenal Glands: Suprarenal Glands: Continents from Top to Bottom:
- Adrenal cortex
- Adrenal medulla
- Kidney
- Ureter
(All connected to blood vessels)
Adrenal Glands: Location and Structure
Each gland has two parts:
- An outer portion, the adrenal cortex.
• Secretes corticosteriods or steriods, chemicals derived from cholesterol. - An inner portion, adrenal medulla.
• Secretes catecholamines chemicals derived from amino acids.
Function: Adrenal Cortex Secretes
• Glucocorticoids: influence metabolism of sugars, fats, and proteins (cortisol) and are anti-inflammatory (cortisone). Influences -SUGAR.
• Mineralocorticoids: regulate electrolytes.
- Aldosterone: reabsorption of
sodium/excretion of potassium. Influences- SALT.
• Gonadocorticoids: androgens and estrogens. Influences-SEX.
Function: Adrenal Medulla Secretes
• Two types of catecholamine hormones:
- Epinephrine (adrenaline): increases heart rate and blood pressure, dilates bronchial tubes, releases glucose from storage.
- Norepinephrine (noradrenaline):
constricts vessels to raise blood pressure. - Both are sympathomimetic agents.
The Adrenal Cortex (Corticosteroids) Secretions:
- Glucocorticoid: Cortisol: Increases blood glucose.
- Mineralocorticoid: Aldosterone: Increases salt (sodium) reabsorption.
- Sex hormones: Androgen and Estrogen: Sexual characteristics.
The Adrenal Medulla (Catecholamines) Secretions:
- Epinephrine (adrenaline)
- Norepinephrine (noradrenaline)
- Both are Sympathomimetic
Pancreas
• Located near and partially behind the stomach.
• Exocrine and endocrine organ.