Chapter 24 Flashcards

1
Q

What nutritional condition is associated with muscle disease?

A

Vitamin E deficiency

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2
Q

What forms of CK are their?

A

2 subunits
M - muscle
B - brain
CK1 (BB) - CNS
CK2 (MB) - cardiac
CK3 (MM) - skeletal

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3
Q

CK half life

A

2-4 hours

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4
Q

Non-pathological causes CK elevation

A

Spurious - haemolysis
Age - higher in puppies (normal by 7 months)
Surgery
IM injection
Recumbency

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5
Q

AST half life?

A

12 hours

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6
Q

How can haemoglobinuria and myoglobinuria be differentiated?

A

With myoglobinuria, plasma is usually clear
By adding ammonium sulphate - precipitates haemoglobin and leaves myoglobin in solution

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7
Q

What infectious diseases are associated with myositis?

A

Neospora
Toxo
Leish
Sarcocystis
Trypanosoma cruzi

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8
Q

What are the causes of lactic acidaemia?

A

Secondary to extreme muscle activity, sepsis, hypovolaemia
Primary enzyme defect - pyruvate dehydrogenase phosphatase 1 deficiency, pyruvate decarboxylase, enzymes of respiratory chain of Kreb’s cycle

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