Chapter 24/ Introduction to viruses that infect humans: The DNA Viruses

Question 1

What is true about Poxviruses?

1. Produce eruptive skin pustules (pocks or pox) that leave scars
2. Largest and most complex animal viruses
3. Have the largest genome of all viruses
4. Multiply in cytoplasm in factory areas
5. All the above

Answer 1

5. All the above

Question 2

When a herpes infection causes eye infection resulting in Inflammation, sharp pain, conjuntivitis, and gritty feeling in the eye this is known as…

Answer 2

Herpetic keratitis
(ocular herpes)

Question 3

Herpetic whitlows are ____ infections of the _____
1. pox, oral cavity
2. CMV,lymph nodes
3. EBV,skin
4. herpes,fingers

Answer 3

4. herpes,fingers

Question 4

fever blisters and genital infections are caused by

1. Herpes simplex 1 and 2 (HSV)
2. Herpesvirus 3
3. Herpesvirus 4
4. Herpesvirus 5

Answer 4

1. Herpes simplex 1 and 2 (HSV)

Question 5

Most RNA viruses multiply in and are released from the cytoplasm.

TRUE or FALSE

Answer 5

TRUE

Question 6

Which of the following viruses causes chronic persistent infection?
1. hepatitis B
2. smallpox
3. parvovirus
4. varicella - zoster virus

Answer 6

1. hepatitis B

Question 7

Recurrent infection of Herpes simplex can be triggered by
1. UV radiation
2. gas
3. stress
4. 5 and 1
5. alcohol use and drug use
6. 1 and 3

Answer 7

6. 1 and 3

Question 8

______ is an effective treatment for herpes simplex lesions
1. Amantadine
2. Interferon
3. Acyclovir
4. Cortisone

Answer 8

3. Acyclovir

Question 9

In general, zoonotic viral diseases are _____ in humans

1. mild and asymptomatic
2. self -limited
3. severe and systemic
4. not contagious

Answer 9

3. severe and systemic

Question 10

Viruses that remain as a separate stable genetic element are called

Answer 10

episomes

Question 11

fever blisters or cold sores are referred to as____ ______

Answer 11

Herpes labialis

Question 12

Viruses that last longer term and can last anywhere from years to entire life is called

Answer 12

Persistant infections

Question 13

HSV-1 enters _____nerve

Answer 13

5th cranial

Question 14

Which virus is used in smallpox vaccination?
1. variola
2. vaccinia
3. cowpox
4. varicella

Answer 14

2. vaccinia

Question 15

herpes zoster is also known as

Answer 15

shingles

Question 16

Molluscipoxvirus causes what common skin disease?

Answer 16

molluscum contagiosum

Question 17

Virus is detectable in tissue samples and is still multiplying at a slow rate but symptoms of infection are usually mild or absent. This is labeled as a ____ infection

Answer 17

Chronic

Question 18

When Reactivation of the chicken pox occurs, it is called ____ ____

Answer 18

(shingle) orHerpes zoster

Question 19

_____ infections result when the virus enters a dormant phase inside host cells and becomes inactive after a lytic infection.

Answer 19

Latent

Question 20

All RNA viruses are single-stranded except for dsRNA ______

Answer 20

reoviruses

Question 21

Adenoviruses are the agents of
1. hemorrhagic cystitis
2. keratoconjuntivitis
3. common cold
4. all of these

Answer 21

4. all of these

Question 22

implicated in Kaposi sarcoma
1. Herpesvirus 8
2. Herpesvirus 3
3. Herpesvirus 4
4. Herpesvirus 6 and 7

Answer 22

1. Herpesvirus 8

Question 23

Neonatal herpes simplex is usually acquired through
1. contaminated mothers hands
2. other babies in the newborn nursery
3. crossing the placenta
4. an infected birth canal

Answer 23

4. an infected birth canal

Question 24

Most DNA viruses are budded off the nucleus
TRUE or FALSE

Answer 24

TRUE

Question 25

HSV-2 enters ______ spinal nerve trunk ganglia

Answer 25

lumbosacral

Question 26

Which of the following viruses can be oncogenic in humans 1. papillomavirus 2. Epstein-Barr virus 3. adenovirus 4. both a and b

Answer 26

4. both a and b

Question 27

Epstein-Barr virus (EBV), associated with infection of the lymphoid tissue 1. Herpes simplex 1 and 2 (HSV) 2. Herpesvirus 3 3. Herpesvirus 4 4. Herpesvirus 5

Answer 27

3. Herpesvirus 4

Question 28

Which of the following is NOT caused by a poxvirus? A. Molluscum contagiosum B. Smallpox C. Cowpox D. Chickenpox

Answer 28

D. Chickenpox

Question 29

Small pox can be highly virulent, cause toxemia, shock, and intravascular coagulation. This would be called ____ _____

Answer 29

Variola major

Question 30

What herpesvirus is most commonly associated with a dangerous fetal infection 1. herpes simplex 2. herpes zoster 3. EBV 4. CMV

Answer 30

4. CMV

Question 31

Varicella and zoster is caused by 1. the same virus 2. two different strains of VZV 3. herpes simplex and herpes zoster 4. CMV and VZV

Answer 31

1. the same virus

Question 32

cytomegalovirus (CMV), infects the salivary glands and other viscera 1. Herpes simplex 1 and 2 (HSV) 2. Herpesvirus 3 3. Herpesvirus 4 4. Herpesvirus 5

Answer 32

4. Herpesvirus 5

Question 33

Herpes simplex 1 usually causes _____, and herpes simplex2 usually causes _____ A. cold sores, genital herpes B. fever blisters, cold sores C. canker sores, fever blisters D. shingles, stomatitis

Answer 33

A. cold sores, genital herpes

Question 34

A syndrome characterized by fever and lymphocytosis, which somewhat similar to Epstein - Barr virus is called

Answer 34

Cytomegalovirus mononucleosis

Question 35

All DNA viruses are double-stranded except for ______which have ssDNA

Answer 35

parvoviruses single stranded

Question 36

A common sign of hepatitis is 1. liver cancer 2. jaundice 3. anemia 4. bloodshot eyes

Answer 36

2. jaundice

Question 37

Parvoviruses are unique because they contain 1. a double-stranded RNA genome 2. reverse transciptase 3. a single - stranded DNA genome 4. an envelope without spikes

Answer 37

3. a single - stranded DNA genome

Question 38

Animal viruses are categorized according to what 3 factors?

Answer 38

-nucleic acid (DNA/RNA) -capsid - presence or absence of envelope

Question 39

Benign epithelial growths on the skin of fingers are called 1. polyomas 2. verrucas 3. whitlows 4. pox

Answer 39

2. verrucas

Question 40

Molluscipoxvirus is transmitted by ____ ____ and ____

Answer 40

direct contact and fomites

Question 41

A virus associated with chronic liver infection and cancer is 1. hepatitis C 2. hepatitis B 3. hepatitis A 4. both a and b

Answer 41

4. both a and b

Question 42

Two types of persistence viral infections are....

Answer 42

Chronic viral infections and latent viral infections

Question 43

varicella-zoster virus (VZV), chickenpox and shingles 1. Herpes simplex 1 and 2 (HSV) 2. Herpesvirus 3 3. Herpesvirus 4 4. Herpesvirus 5

Answer 43

2. Herpesvirus 3