Chapter 24.2 Part 2 Flashcards

(50 cards)

1
Q

What percentage of lymphocytes in the blood are natural killer?

A

About 5-10%

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2
Q

Destroy microbes & tumor cells, present in lymph nodes & red bone marrow

A

Natural killer cells (NK)

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3
Q

Defense response of the body tissue damage?

A

Inflammation

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4
Q

Inflammation helps restore?

A

Homeostasis

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5
Q

Four signs and symptoms of inflammation are?

A

Redness, heat, swelling and pain.

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6
Q

Pocket of dead cells=

A

Pus

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7
Q

Damage to tissue, mast cells in connective tissue and basophils and plates release?

A

Histamine

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8
Q

Increased permeability of capillaries causes leakage of clotting proteins into tissues, the resulting clot may..

A

Isolate the invading microbes and toxins.

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9
Q

Shortly after the inflammatory process starts..

A

Phagocytes are attracted to the site of injury (neutrophils & macrophages)

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10
Q

Forms a physical barrier to the entrance of microbes.

A

Epidermis of skin

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11
Q

Inhibit the entrance of many microbes, but not as effective as intact skin.

A

Mucous membrane

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12
Q

Tears dilute and wash away irritating substances and microbes

A

Lacrimal apparatus

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13
Q

Antimicrobial substances in perspiration, tears, saliva, and tissue fluids.

A

Lysozyme

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14
Q

Abnormally high body temperature that occurs because the hypothalamic thermostat is reset

A

Fever

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15
Q

Intensifies the effects of interferons, inhibits growth of some microbes, speed up body reactions that aid repair

A

Fever

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16
Q

Fever causing substances from macrophages?

A

Inteleukin-1

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17
Q

Any substance such as microbes, foods, drugs, pollen or tissue

A

Antigen

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18
Q

Includes cell tissues that carry out immune responses.

A

Immune system

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19
Q

Normally a persons adaptive immune system cells recognize and do not attack there own tissues and..

A

Self-tolerant

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20
Q

Cells that carry out adaptive immune responses are lymphocytes called?

A

B cells and T cells

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21
Q

B and T cells originate in..

A

Red bone marrow

22
Q

Molecules capable of recognizing and binding to specific antigens

A

Antigen receptors

23
Q

T cells that directly attack invading antigen

A

Cell-mediated immune response

24
Q

Aid- both cell and antibody mediated responses.

A

Helper T cells

25
Located on plasma membrane surface of most body cells are protein “self antigens” known as
Major histicompatibility complex (MHC) antigens
26
Major histocompatibility complex (MHC) is unique to each individual unless?
You have a identical twin
27
Reasons why tissues may be rejected when they are transplanted from one person to another?
MHC antigens
28
Invest and digest the antigen into fragments in vesicles.
Antigen presenting cell
29
Co-stimulator to T cells is
Inteluekin-1
30
T cells divided many times the resulting population of identical cells, termed
Clone
31
Three types of major T cells?
Helper T cells, cytotoxin T cells, memory T cells.
32
Helper T cells release
IL2, attract phagocytes, stimulate macrophages and B cells.
33
To reduce risk of rejection, organ transplants receive
Immunosuppressive drugs
34
Derived from fungus, inhibits secretion of interleukin-2 by helper T cells.
Cyclosporine
35
Work against tumor cells transplanted cells and infected cells, recognize and bind to infected target cells
Cytotoxic T cells
36
Remain in lymphatic system tissue long after the original infection and are able to recognize the original
Memory T cells
37
Virus that destroys T cells
HIV
38
Ready to respond quickly if antigen met again
Memory B cells
39
The binding of a antibody to its antigen neutralizes some bacterial toxins and prevents attachment of some viruses
Neutralizing antigen
40
Some antibodies cause bacteria to lose their motility, which limits bacterial spread into nearby tissues
Immobilizing bacteria
41
Connect pathogens to one another
Agglutinating
42
Antigen-antibody complex’s activate complement proteins, which then work to remove microbes though
Activating complement
43
Binding attracts phagocytes
Enhancing phagocytes
44
Long lasting antibodies and very long lived lymphocytes.
Immunological memory
45
Antibodies produced during secondary reasons stronger than the first?
True- larger and quicker
46
Can the primary response be acquired naturally?
Yes
47
Artificially acquired immunity
Vaccination
48
Describe effects of aging on the immune system
Thymus atrophies, fewer responsive T cells, thus poorer B cell response
49
Why is it important for elderly people to get their flu shot vaccinations each year
Poorer response to newer infections
50
Lymphedema occurs in ____% mastectomies with axillary Dissections.
12-15%