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1

Interchange of genetic material between homologous chromosomes during synapse and meiosis

crossover

2

a disease associated with formation of cell-mediated or humoral immunity against the subjects own cells or tissue components

autoimmune disease

3

the inactivated X chromosome that is applied to the nuclear membrane in the female. Sex Chromatin body.

barr body

4

the genes of histocompatibility complex and the antigens that they determine on the surface of cells

HLA system

5

the structure that joins each pair of chromatids formed by chromosome duplication

centromere

6

the gene present on the X chromosome

sex-linked gene

7

germ cells in a late stage of sperm development just before complete maturation to form mature sperm

spermatids

8

cells lining the ovarian follicles

granulosa cells

9

same as recombinant DNA technology

gene splicing, genetic engineering

10

structure extruded during the meiosis of the oocyte. Contains discarded chromosomes and a small amount of cytoplasm

polar body

11

the general term referring to either ovary or the testis

gonad

12

a noncoding part of a chromosomal DNA chain

intron

13

unique histocompatability antigens (self-antigens) on the surface cells. Also called major histocompatibility complex (MHC) antigens

human leukocyte antigens

14

the type of cell division of most cells in which chromosomes are duplicated in the daughter cells and are identical with those in the parent cell. the characteristic cell division found in all cells in the body except for gametes.

mitosis

15

a systemic disease primarily affecting the synovium with major manifestations in the small joints

rhumatoid arthritis

16

methods for combining gene from one organism, with genes of another organism

recombinant DNA technology

17

the position of a gene on a chromosome. different forms (alleles) of the same gene are always found at the same locus on a chromosome

locus

18

pairing of homologous chromosomes in meiosis

synapse

19

an arrangement of chromosomes from a single cell arrangement in pairs in descending order according to size of the chromosomes and the positions of the centromeres

karyotype

20

reproductive cells, eggs, and sperm each containng 23 chromosomes which unite during fertilization to form a zygote containing 46 chromosomes

gametes

21

the total of all the genes contained in a cell's chromosomes.

genome

22

a term applied to genes located on the X chromosome in the male

hemizygous

23

a gene that expresses a trait on the heterozygous state

dominant gene

24

a small circular DNA molecule separate from the main bacterial chromosome.

plasmid

25

a group of genes on chromosome 6 that determine the antigens on the surface cells

major histocompatability complex

26

a chromosome other than a sex chromosome

autosome

27

one of several related genes that may occupy the same locus on a homologous chromosome

allele

28

the development of mature eggs and sperm from precursor cells

gametogenesis

29

a protein or enzyme specified (coded) by a gene

gene prodcut

30

a special type of cell division occurring in gametes (ova and sperm) in which the number of chromosomes is reduced by one-half in the ovum and sperm

meiosis