Chapter 3 Flashcards

(63 cards)

0
Q

Functions of plasma membrane proteins: channels

A

water-filled passageway

  • highly selective (water soluble can enter, very small)
  • can open or close
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1
Q

cell membrane: structure

A

phospholipid bilayer

  • cholesterol - stability
  • proteins:
    • integral - spanning entire membrane)
    • peripheral - sticking out
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2
Q

Functions of plasma membrane: carrier molecules

A

transport substances in or out that are not free to pass

- only open to one side at a time (not ECF and ICF at the same time)

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3
Q

functions of plasma membrane: membrane bound enzymes

A

control chemical reactions

ex. Ache

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4
Q

functions of plasma membrane: receptor sites

A

can bind with extracellular signals

  • use lock and key theory (will bind if messenger fits with receptor)
  • have to be complementary
  • ex. prolactin knows to bind to breast cells cause they fit
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5
Q

functions of plasma membrane: cell adhesion molecules

A

grip other cells

  • allows cells to form tissues and to stick to various things (ex. WBC)
  • protrude from plasma membrane
  • ex. Cadherin (velcro)
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6
Q

functions of plasma membrane: ID tags

A
  • proteins often with CHOs (glycoproteins)
  • helps cells to recognize of the same type
  • prevent overgrowth of tissue - “contact inhibition” (once mitosis is filled in all the areas, they stop growth)
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7
Q

passive

A

does NOT require ATP

- relies on molecular motion

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8
Q

Active

A

requires ATP

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9
Q

Unassisted

A

does not require help/assistance

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10
Q

assisted/carrier mediated

A

needs a carrier molecule (needs help)

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11
Q

diffusion

A
  • unassisted
  • the movement of molecules from a high concentration to a low concentration
  • molecules move DOWN their concentration gradient
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12
Q

Osmosis

A
  • unassisted
  • diffusion of water DOWN its concentration gradient
  • high concentration to a low concentration
  • osmotic pressure = pulling
  • water being pulled toward the higher solute concentration
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13
Q

tonicity

A

measure of solute concentration

- referring to the solute concentration in the ECF

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14
Q

isotonic

A

ICF and ECF solute concentration is =

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15
Q

hypotonic

A

the ECF has a lower concentration of solutes than the ICF

- water is drawn towards higher solute concentration

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16
Q

Hypotonic: The osmotic pressure is ________ the cell; therefore water will tend to ______ the cell due to osmosis

A

higher in

enter

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17
Q

hypertonic

A

the ECF has a higher concentration of solutes than the ICF

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18
Q

hypertonic: the osmotic pressure is _________ the cell; therefore water will tend to ______ the cell due to osmosis

A

higher outside

leave

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19
Q

filtration

A

the movement of substances through a membrane as a result of a higher hydrostatic of one side of the membrane
- ex. coffee (directing hydrostatic pressure through membrane -> water pushes coffee grounds through filter into the cup)

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20
Q

example of filtration in the body

A

cells are filtered out of the blood stream

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21
Q

carrier mediated transport

A

can be active or passive

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22
Q

characteristics that determine the kind and amount of material that can be transferred across the membrane are_______, ________, and ________

A

specificity
saturation
competition

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23
Q

specificity

A

shapes match (carrier molecule for amino and another carrier molecule for glucose - shapes have to match)

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24
satuaration
``` transport maximum (TM) - mini van analogy - can't carry anymore no matter how much it is flooded (wine analogy) ```
25
competition
similar molecules compete
26
facilitated diffusion
substances move from a HIGHER concentration to a LOWER concentration - requires carrier molecule - no ATP - ex. GLUT
27
does facilitated diffusion require ATP?
No
28
active transport
moves a substance UP its concentration gradient by using a carrier molecule - requires ATP ex. Na+/K+ pump
29
vesicular transport: 2 types
endocytosis | exocytosis
30
endocytosis
import
31
exocytosis
export
32
Endocytosis: Phagocytosis
cell-eating - ATP required - occurring all the time
33
Endocytosis: Pinocytosis
cell-drinking
34
Exocytosis
release of secretory products | " how do we get things out of the cell?"
35
membrane potential
difference in charges between ICF and ECF or the separation of opposite charges across plasma membrane
36
membrane potential is measured in ______
mV
37
resting membrane potential
constant membrane potential present in cells at rest - separation of charges in a cell at rest - nerve cell RMP = -70 mV
38
The cell membrane is more permeable to ___ than to ____
K+ | Na+
39
K+ leaks/diffuses out at a ______ rate
faster
40
effect of sodium/potassium pump on membrane potential: pumps ______ in and ________ out
2K+ | 3Na+
41
passive ______ and the active ________ work together to establish the RMP
diffusion | Na+/K+ pump
42
nerve and muscle cells are excitable cells and have the ability to __________ in their membrane potential when excited
produce rapid changes | - this gives us nerve impulses and muscle contractions
43
proteins that span the whole membrane are called what?
integral
44
where are the peripheral proteins
they stick out
45
simply state how active transport is different from passive transport
active transport requires ATP and passive transport does not use ATP
46
is osmosis passive or active
passive
47
define diffusion
the movement of molecules from a high concentration to a low concentration
48
define osmosis
high concentration of water --------> low concentration of water
49
cells in a hypertonic solution will _____ water as a result of osmosis
lose
50
water molecules move _____ the higher osmotic pressure
toward
51
tonicity refers to the solute concentration in the ___
ECF
52
in carrier mediated transport, we talk about specificity of the molecules. What does this mean?
shapes have to match - lock and key method
53
what is TM
transport maximum | minivan analogy
54
how does the example of TM in class about glucose in the urine demonstrate the above
if there is too much glucose in the urine, TM will grab the g molecules and pull them back into the blood stream
55
membrane potential is defined as
difference in charges between ICF and ECF or the separation of opposite changes across plasma membrane
56
what two cell types are excitable
nerve and muscle cells | - have ability to produce rapid changes in their membrane potential when excited
57
resting membrane potential is defined as
constant mp present in cells at rest
58
resting potential is about ____ mV for the normal cell
-70
59
so that means that K+ wants to diffuse _____ and Na+ wants to diffuse ___
out | in
60
how many Na+ are pumped
3 out
61
how many K+ are pumped
2 IN
62
the cell membrane is leakier to ___ than to ___
K+ | Na+