Chapter 4 - Regulation of Gene expression (2019) - Evals #2 by Keim Flashcards
(43 cards)
Codes the DNA polypeptide
Exon
First protein that binds to the DNA
TF IID
Which of the following is NOT involve in translation?
a. DNA
b. mRNA
d. Protein
DNA
What step in gene expression with a genetic code on the mRNA is read by your tRNA and then amino acid is carried by tRNA are added in nascent
polypeptide chain?
Translation
All biological components of structures in the directly corresponding their
function, which of the following is the CORRECT statement regarding
chromosomal structure?
Histone and scafolds condensed DNA into a size that is fit into the nucleus.
Translation of the mRNA on ribosomes always begin at which codon and what amino acid it translates to:
AUG — methionine
True or False:
The central dogma of molecular biology states that genetic information flows UNIDIRECTIONALLY from DNA to proteins.
True
What is a gene?
A DNA segment that contains all genetic information required to encode RNA and protein molecules
A promoter is:
a. Determines the site for initiation of transcription
b. Determines Direction of transcription
C. Consists of modules of simple sequences (DNA elements)
D.ALL OF THE ABOVE
D. All of the above
Inhibit the activity of transcriptional activators not by interfering w/ DNA binding, but by a direct protein-protein interaction w/ activators:
Quenching
Liver cells perceive the presence of glucagon and stimulate PEPCK gene expression. This illustrates the phenomenon of:
a. Tissue-specific gene expression
b. Forced gene expression
c. Adaptation gene expression
d. Inducible gene expression
D. Inducible gene expression
A cis-acting regulatory element that is required for expression of gene.
Promoter
Most regulated step in gene expression:
Inititation of transcription
Which of the following is not true for Na/K pumps?
In most epithelial cells, the sodium pump is restricted to the apical membrane of a cell.
Which of the following pump runs as an ATP synthase of the inner membrane of the mitochondria? F-type ATPase
F-type ATPase
- The ABC transporters can act as:
all of the above
Acid extruders are stimulated when the cell is acidified, and is inhibited when the cell is alkalinized, hence maintaining pH for proper cell functioning. Which of the following is NOT an acid extruder?
Calcium pumps
Which of the following is NOT a driving force for the Na-Glucose co-transporter?
Hydrolysis of ATP
Which if the following is a primary active transporter?
N/K A
- The tube is separated by an impermeable membrane into two chambers. The left chamber contains 1L of 2 m sodium chloride solution. The right chamber contains 1L of 1 m sodium chloride solution. If the membrane is made permeable to water, then osmotic pressure will cause the net flux of water to go:
from right to left.
Which of the following is true?
Inside the cell, the quantity of positively charged ions is almost exactly equal to the quantity of negatively charged ions.
What protein pathway forms donut-like triads that allow the passage of ions, water and small molecules to diffuse to target cells?
Perforins
The major function of calmodulin in the cells is to act as:
Calcium-binding protein
Electrochemical driving force of potassium: A. Close to zero B. Somewhat positive C. To move potassium outside of the cell D. All of the above
D. All of the above
