chapter 4 - tissues Flashcards

1
Q

A tissue is a ….

A

A tissue is a group of similar cells and extracellular products that perform a common function

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2
Q

The _____ of different tissues varies in structure and function

Generally composed of ___, ___, & ___

__, __, and ___is different across tissues

A

he extracellular matrix of different tissues varies in structure and function
Generally composed of water, protein fibers, dissolved molecules
Composition, volume and consistency is different across tissues

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3
Q

Four types of tissue in the body:

A

Epithelial tissue
Connective tissue
Muscle tissue
Nervous tissue

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4
Q

muscle tissue

general characteristics

A

contractile

receives stimulation from nervous system and/or endocrine system

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5
Q

Muscle tissue

general functions

A

facilitates movement of skeletal or organ walls

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6
Q

muscle tissue

primary germ layer derivative

A

mesoderm

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7
Q

muscle tissue

subtypes

A

skeletal muscle: attached to bones
cardiac muscle: heart
smooth muscle: digestive tract

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8
Q

nervous tissue

two components and brief descriptions

A

neurons: excitable, high metabolic rate, extreme longevity, non mitotic

glial cells: non excitable and mitotic

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9
Q

nervous tissue

functions

A

neurons: control activities and process info

glial cells: support and protect neurons

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10
Q

primary germ layer of nervous tissue

A

ectoderm

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11
Q

epithelial tissue

general characteristics

A

cellular. polar, attached, avascular, innervated, high regeneration capacity

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12
Q

Epithelial tissue

functions

A

covers surfaces

lines insides of organs and body cavities

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13
Q

epithelial primary germ layer

A

ectoderm
mesoderm
endoderm

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14
Q

epithelial tissue

subtypes

A
simple columnar (lining of digestive)
stratified squamous (epidermis of skin)
transitional (lining of bladder)
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15
Q

connective tissue

general characteristics

A

diverse types
all contain cells
protein fibers

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16
Q

connective tissue

functions

A

protects
binds together
supports organs

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17
Q

connective tissue

primary germ layer

A

mesoderm

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18
Q

connective tissue

subtypes

A
adipose  - fat
dense regular  -ligament and tendons
dense irregular - dermis of skin
hyaline cartilage - some joints
fluid  - blood and lymph
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19
Q

Muscle is comprised of cells called ___

When cells are active, internal changes cause them to ___

The result of shortening is ___

Examples: Movement of bones, blood, food, semen, urine

A

Muscle is comprised of cells called fibers

When cells are active, internal changes cause them to shorten

The result of shortening is movement

Examples: Movement of bones, blood, food, semen, urine

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20
Q

skeletal muscles

Skeletal muscle fibers are:
___&___ (some as long as whole muscle)

_____

_____ and _____

Attached to ____ and sometimes skin

A

Skeletal muscle fibers are:

Cylindrical and long (some as long as whole muscle)

Multinucleated

Striated (striped internal appearance) and voluntary

Attached to bones of skeleton and sometimes skin

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21
Q

skeletal muscle

___, ___, & ____fibers
Multiple ___ in periphery of each fiber
Moves ____
Attaches to ____

A

Long, cylindrical, striated fibers
Multiple nuclei in periphery of each fiber
Moves body (voluntary control)
Attaches to bone and/or skin

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22
Q

cardiac muscle

Found in ___

Cells are:
1.
2.
3.
4.

Contraction causes ____

A

Found in wall of the heart (myocardium)

Cells are:

  1. Branched and shorter than skeletal fiber cells
  2. Striated
  3. Involuntary
  4. Attached end-to-end by strong gap junctions at intercalated discs that allow rapid passage of electrical current from one cell to the next during each heartbeat

Contraction causes movement of blood

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23
Q

cardiac muscle

___, bifurcated, & ___ fibers

One or two ___ in center of each fiber

____ between cells

Pumping action moves ___

Located in ____

A

Short, bifurcated, striated fibers

One or two nuclei in center of each fiber

Intercalated discs between cells

Pumping action moves blood

Located in heart wall

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24
Q

smooth muscle

Found in walls of ___

Examples:

Cells are:
Relatively __, ___ in the middle, and ___ at the ends (fusiform)
Not ___
Contraction causes…

A

Found in walls of most internal organs

Examples: Stomach, intestines, urinary bladder

Cells are:
Relatively short, wide in the middle, and tapered at the ends (fusiform)
Not striated
Contraction causes involuntary movement of food, blood, sperm

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25
smooth muscle ___, ___, ____ cells One ___ in center of each cell Moves material through ____ (involuntary) Located in walls of many hollow organs including ____
Nonstriated, short, fusiform cells One nucleus in center of each cell Moves material through internal organs (involuntary) Located in walls of many hollow organs including intestines
26
nervous tissue Two types of cells in nervous tissue:
Two types of cells in nervous tissue: Neurons Glial cells
27
Neurons: Each cell has a prominent cell body, branches of ___ that receive signals, and a long ___ that carries signals toward other cells
Neurons: Nerve cells capable of initiating and conducting electrical activity throughout the body Each cell has a prominent cell body, branches of dendrites that receive signals, and a long axon that carries signals toward other cells
28
Glial cells: ___ and ___ Found in... (3)
Glial cells: Cells that support and protect neurons Communication and control of body functions Found in brain, spinal cord, and nerves
29
nervous tissue Contains neurons with fibrous processes called ___ and ___ and glial cells 3 functions: Located in....
Contains neurons with fibrous processes (dendrites and axons) and glial cells Process and store information, control body systems Located in central (brain, spinal cord) and peripheral nervous systems
30
epithelial tissue Epithelial tissue lines every ____ and all ____ Organs are lined on the __ & ___ by epithelial tissue The majority of ___ are derived from epithelial tissue Epithelial tissue possesses little to no ____
Epithelial tissue lines every body surface and all body cavities Organs are lined on the outside and inside by epithelial tissue The majority of glands are derived from epithelial tissue Epithelial tissue possesses little to no extracellular matrix
31
All epithelia are:
All epithelia are: cellular, polar, attached to a basement membrane, avascular, richly innervated, and regenerative
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Characteristics of Epithelial Tissue
``` cellularity polarity attachment avascularity innervation high regeneration capacity physical protection selective permeability secretion sensation ```
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Cellularity: Composed almost entirely of __ - little ______ | ----Cells are bound together by several types of ______
Cellularity: Composed almost entirely of cells - little extracellular matrix ---Cells are bound together by several types of intercellular junctions
34
Polarity: Epithelial cells have an ___ & a ___ Apical surface is ____ Basal surface is attached to _____ underneath it
Polarity: Epithelial cells have an apical surface and a basal surface Apical surface is exposed Basal surface is attached to connective tissue underneath it
35
epithelial tissue Attachment:
Attachment: Basal surface attaches to basemement membrane - molecules produced by both epithelial and neighboring connective tissues
36
epithelial tissue avascularity
Epithelial tissues lack blood vessels
37
epithelial tissue innervation
Epithelia are richly innervated to detect changes in environment (externally or internally)
38
epithelial tissue high regeneration
Because exposed apical surface is frequently damaged, epithelial cells are quickly replaced
39
epithelial tissue physical protection
Defend against dehydration and abrasion, as well as physical, chemical, and biological agents
40
epithelial tissue selective permeability
Regulate passage of molecules in or out of certain regions of the body
41
epithelial tissue secretion
Secrete substances for use in the body (e.g., hormone) or for elimination from the body (e.g., sweat)
42
epithelial tissue sensation
Possess nerve endings that can detect light, taste, sound, smell, and hearing
43
Specialized Structures of Epithelial Tissue The _____ is a specialized structure of epithelium Found between ___ & _____ Provides __ ____ and anchoring of epithelial tissue Acts as a barrier regulating passage of large molecules between ___ & ____
The basement membrane is a specialized structure of epithelium Found between epithelium and underlying connective tissue Provides physical support and anchoring of epithelial tissue Acts as a barrier regulating passage of large molecules between epithelium and connective tissue
44
Specialized Structures of Epithelial Tissue Epithelial cells are strongly bound to each other on their ___ surfaces by membrane specializations called ___ There are several types of these junctions: (4)
Epithelial cells are strongly bound to each other on their lateral surfaces by membrane specializations called intercellular junctions ``` There are several types of these junctions: Tight junctions Adhering junctions Desmosomes Gap junctions ```
45
tight junctions Encircle cells near... Prevent molecules from .... So that molecules must go through epithelial cells rather than in between them “Gatekeepers” between an ....
Encircle cells near their apical surface Prevent molecules from traveling between epithelial cells So that molecules must go through epithelial cells rather than in between them “Gatekeepers” between an external and internal environment
46
adhering junctions Formed completely around the cell deep to the ____ ___ act like a purse string to stabilize the apical surface of the epithelial cell
Formed completely around the cell deep to the tight junction Microfilaments act like a purse string to stabilize the apical surface of the epithelial cell
47
desmosomes -Like a ___ between adjacent cells Appear at locations of ... Consist of a ____ on each of the apposed cell membranes with a fine network of proteins spanning the intercellular space between the plaques On the cytoplasmic side, intermediate filaments attach to the plaques and provide ___ & ____ Some basal epithelial cells have _____ anchoring them to basement membrane
Like a button or snap between adjacent cells Appear at locations of mechanical stress between cells sharing this type of junction Consist of a thickened protein plaque on each of the apposed cell membranes with a fine network of proteins spanning the intercellular space between the plaques' On the cytoplasmic side, intermediate filaments attach to the plaques and provide support and stability Some basal epithelial cells have hemidesmosomes anchoring them to basement membrane
48
Gap junctions span the intercellular space between... A Connexon is a group of membrane proteins... The ____ connects the cytoplasms of the two cells Allow adjacent cells to _____ by the flow of ions and small molecules
Gap junctions span the intercellular space between neighboring cells A Connexon is a group of membrane proteins that forms a pore The fluid filled pore connects the cytoplasms of the two cells Allow adjacent cells to communicate with each other by the flow of ions and small molecules
49
Classification of Epithelial Tissue Many different types of epithelial tissue Classified according to two criteria: 1. 2.
Classification of Epithelial Tissue Many different types of epithelial tissue Classified according to two criteria: Number of layers of cells Shape of the cells
50
classification by number of cell layers
simple epithelium stratified epithelium pseudostratified epithelium
51
Simple epithelium: Consists of ... All cells have ....
Simple epithelium: Consists of a single layer of cells All cells have an apical surface and attach to the basement membrane
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Stratified epithelium: Consist of ... Not all cells have _____ nor do all cells attach to____
Stratified epithelium: Consist of two or more layers of cells Not all cells have an apical surface nor do all cells attach to the basement membrane
53
Pseudostratified epithelium: Appears to have____, but all cells attach to _____ A subtype of _____
Pseudostratified epithelium: Appears to have multiple layers, but all cells attach to the basement membrane A subtype of simple epithelium
54
classification by cell shape
Squamous Cuboidal Columnar
55
Squamous: Cuboidal: Columnar:
Squamous: Flat, wide, and somewhat irregular in shape Cuboidal: About the same size on all sides; nucleus is usually centrally located Columnar: Taller than they are wide; nucleus is oval and located in basal region of the cell
56
simple squamous epithelium what is it? allows for?
Single layer of flat cells | Allows for rapid exchange
57
simple cuboidal epithelium what is it? allows for?
Single layer of boxy cells | Allows for absorption, secretion
58
Nonciliated Simple Columnar Epithelium - what is it? - No ____ - Allow ___ & ____ - Especially secretion of ____ -Example: lining of intestine
Single layer of tall, narrow cells No cilia present Allow absorption and secretion Especially secretion of mucin Example: lining of intestine
59
Ciliated Simple Columnar Epithelium - Single layer of ... - Allow for... - Example: uterine tube
- Single layer of tall, narrow, ciliated cells - Allow for secretion, movement of material across free surface - Example: uterine tube
60
Pseudostratified Columnar Epithelium Single layer of ... - Some examples are ____ what is the function?
- Single layer of narrow cells with varying heights - Some examples are ciliated Protection; ciliated form secretes mucin, moves mucus
61
Stratified Squamous Epithelium Multiple ____, apical cells are ____ Apical cells may or may not be _____
Multiple layers, apical cells are flat Apical cells may or may not be keratinized
62
Keratinized Stratified Squamous Epithelium ``` Multiple ... Apical cells are _____ Superficial layers of cells contain ... Function: ___ Example: epidermis of skin ```
``` Multiple layers of cells Apical cells are dead, flat Superficial layers of cells contain tough, protective keratin Function: protection Example: epidermis of skin ```
63
nonkeratinized stratified squamous epithelium Multiple.... Flat, apical cells are ... Function: _____ Example: lining of vagina
Multiple layers of cells Flat, apical cells are alive and moist Function: protection Example: lining of vagina
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Stratified Cuboidal Epithelium Multiple.... apical cells are ____ ___ and _____ Example: lining of sweat gland duct
Multiple layers of cells, apical cells are boxy Protection and secretion Example: lining of sweat gland duct
65
stratified columnar epithelium Multiple.... apical cells are _____ ___ and _____ Example: part of male urethra
Multiple layers of cells, apical cells are elongated Protection and secretion Example: part of male urethra
66
transitional epithelium Multiple... apical cell shape .... Can __ or ____depending on how ____it is Lining of urinary tract
Multiple layers apical cell shape varies depending on degree of stretch Can distend or recoil depending on how stretched it is Lining of urinary tract
67
two types of glands
endocrine | exocrine
68
glands ___ or ____ Perform a ____ fxn Produce .....
Individual cells or multicellular organs Perform a secretory function Produce mucin, hormones, enzymes, waste products
69
endocrine do not? secrete directly into? exocrine possess? secrete products into?
Endocrine glands do not possess ducts; secrete directly into interstitial fluid or bloodstream Exocrine glands possess ducts and their cells secrete products into their ducts
70
Structure of Exocrine Glands __ ___ are unicellular exocrine glands Multicellular exocrine glands are often enclosed in a ___ --Inside the capsule, the gland is divided into ____ --A connective tissue ___ does what? --Microscopic lobules contain ...
Goblet cells are unicellular exocrine glands Multicellular exocrine glands are often enclosed in a fibrous capsule --Inside the capsule, the gland is divided into lobes --A connective tissue stroma supports and organizes the gland --Microscopic lobules contain secretory acini and ducts
71
Classification of Exocrine Glands 1. Gland structural categorization depends on the ___ of the duct and the ____of the secretory portion - -Ducts type distinguishes ___ from ___ - -Secretory portion can be ___, ___ or ____
1. Gland structural categorization depends on the complexity of the duct and the shape of the secretory portion - --Ducts type distinguishes simple from compound glands - ---Secretory portion can be tubular, acinar or tubuloacinar
72
Classification of Exocrine Glands Types of secretion mechanisms 3 of them
Types of secretion mechanisms - --Merocrine: secrete products from vesicles via exocytosis - ---Holocrine: cell accumulates product, then disintegrates - ---Apocrine: product stored in apical part of cell that pinches off
73
secretion mech of exocrine Merocrine: Holocrine: Apocrine:
Merocrine: secrete products from vesicles via exocytosis Holocrine: cell accumulates product, then disintegrates Apocrine: product stored in apical part of cell that pinches off
74
Classification of Exocrine Glands 2. Gland secretion types are ___, ___ or ____ - -Serous glands produce ... - -Mucous glands secrete ____ - -Mixed glands produce a mixture of ___ and ____ seretions (e.g. salivary glands under oral cavity)
Gland secretion types are serous, mucous, or mixed - --Serous glands produce watery fluids (such as sweat) - --Mucous glands secrete mucin - --Mixed glands produce a mixture of watery and mucoid secretions (e.g. salivary glands under oral cavity)
75
Connective tissue is the most .... It is the ___of the body Includes ...
Connective tissue is the most diverse, abundant, widely distributed, and structurally varied of the four main tissue types It is the “glue” of the body Includes blood, tendons, ligaments, fat, bones, cartilage
76
characteristics of connective tissue
cells protein fibers ground substance
77
connective tissue Cells: Different ___ in different types of ____ Examples include ___ ___ ___ Protein fibers: ___ ___ ___ Ground substance: A mixture of ___ & ____with variable amounts of ___ & ____ -Protein fibers and ground substance comprise the _____
Cells: Different cells in different types of connective tissue Examples include fibroblasts, osteocytes, and adipocytes Protein fibers: Elastic fibers, collagen, reticular fibers Ground substance: A mixture of proteins and carbohydrates with variable amounts of salts and water -Protein fibers and ground substance comprise the extracellular matrix
78
Functions of connective tissue | 6
``` Physical protection Support and structural framework Binding of structures Storage Transport Immune protection ```
79
development of connective tissue Arises from ___ Two types of embryonic CT: 1. 2.
Arises from mesoderm Two types of embryonic CT: 1. Mesenchyme: The source of all adult connective tissue 2. Mucous connective tissue: Found in umbilical cord
80
classification of connective tissue Types present after birth can be classified into three broad categories:
Types present after birth can be classified into three broad categories: 1. Connective tissue proper 2. Supporting connective tissue 3. Fluid connective tissue
81
Connective tissue proper includes multiple subtypes Subtypes vary in ___ & ____ and in properties of ____
Connective tissue proper includes multiple subtypes Subtypes vary in number and types of cell and in properties of extracellular matrix
82
There are two groups of cells in connective tissue proper: 1. ____ cells 2. ____cells
There are two groups of cells in connective tissue proper: Resident cells: Include fibroblasts, adipocytes, fixed macrophages, and mesenchymal cells Wandering cells: Include mast cells, plasma cells, free macrophages, and other leukocytes
83
protein fibers of connective tissue proper Three types of fibers produced by cells and secreted into the extracellular matrix:
collagen fibers, elastic fibers, reticular fibers
84
Collagen fibers: ___, ___ & ___ cables - -Collagen is the most ... - -Called “__ ___” (e.g. in tendons and ligaments)
Collagen fibers: long, strong, flexible cables - -Collagen is the most abundant protein in human body - -Called “white fibers” (e.g. in tendons and ligaments)
85
Elastic fibers: ___ than collagen, ___ easily, ___and ___ Allow structures such as blood vessels to __ ___
Elastic fibers: Thinner than collagen, stretch easily, branch, and rejoin Allow structures such as blood vessels to stretch and relax
86
Reticular fibers: ___ than collagen fibers; form a ___/___ framework Found in the stroma of organs with ___ ____ such as liver, lymph nodes, and spleen
Reticular fibers: Thinner than collagen fibers; form a branching, woven framework Found in the stroma of organs with abundant spaces such as liver, lymph nodes, and spleen
87
Ground Substance of Connective Tissue Proper A combination of ___ & ___ Texture is usually ___ Additional content such as ___ & ___ can result in a texture anywhere from ___ to ___
A combination of proteins and carbohydrates Texture is usually gelatinous Additional content such as water and salts can result in a texture anywhere from semi-fluid (adipose) to hard (bone)
88
categories of connective tissue
Connective tissue proper is classified into two categories: Loose connective tissue Dense connective tissue
89
Loose connective tissue: Serves as the body’s ____, found in spaces around ___ Types include
Loose connective tissue: Serves as the body’s packing material, found in spaces around organs Types include areolar, adipose, and reticular
90
Dense connective tissue: ___, has ... Types include...
Dense connective tissue: Strong, has fibers (mostly collagen) packed tightly together Types include dense regular, dense irregular, and elastic
91
Areolar Connective Tissue describe it ___ and ____; connects ____ to deeper tissues Example: papillary layer of dermis
Scattered fibroblasts, abundant ground substance, web of fibers Surrounds and protects; connects epithelia to deeper tissues Example: papillary layer of dermis
92
Adipose Connective Tissue what is it? Stores ___, cushions ___, and ___ Example: subcutaneous fat
Tightly packed adipocytes Stores energy, cushions organs, insulates Example: subcutaneous fat
93
Reticular Connective Tissue Scattered ____, _____, reticular fibers; ___/___ substance Provides __ ___ Example: stroma of spleen
Scattered fibroblasts, white blood cells, reticular fibers; gel-like ground substance Provides supportive framework Example: stroma of spleen
94
Dense Regular Connective Tissue Densely packed ____, fibroblasts, scarce _____ Resists ___ in ____ Example: tendons
Densely packed parallel collagen fibers, fibroblasts, scarce ground substance Resists stress in one direction Example: tendons
95
Dense Irregular Connective Tissue ____ collagen fibers, fibroblasts, ___ substance Resists ___ in ____ Example: dermis
Randomly arranged collagen fibers, fibroblasts, ground substance Resists stress in all directions Example: dermis
96
Elastic Connective Tissue Many ____, fibroblasts, ____ substance Allows ____ Example: walls of large, elastic arteries
Many branching elastic fibers, fibroblasts, ground substance Allows stretching Example: walls of large, elastic arteries
97
Two types of supporting connective tissue:
Two types of supporting connective tissue: Cartilage Bone
98
cartilage Firm, gel-like extracellular matrix composed of... Cells are called ____ and they occupy small spaces enclosed by their extracellular matrix called lacunae ___ and ____ to provide ___ and withstand deformation Usually covered by ____ ---Dense irregular connective tissue and stem cells for cartilage growth
Firm, gel-like extracellular matrix composed of protein and ground substance Cells are called chondrocytes Chondrocytes occupy small spaces enclosed by their extracellular matrix called lacunae Strong and resilient to provide support and withstand deformation Usually covered by perichondrium ---Dense irregular connective tissue and stem cells for cartilage growth
99
There are three types of cartilage:
There are three types of cartilage: Hyaline cartilage Fibrocartilage Elastic cartilage
100
hyaline cartilage __ ___; chondrocytes in lacunae _____ type of cartilage, but also the ____ Smooths ___ ___, model for ____ Example: articular cartilage of long bones
Glassy matrix; chondrocytes in lacunae Most common type of cartilage, but also the weakest Smooths joint surfaces, model for bone growth Example: articular cartilage of long bones
101
Fibrocartilage ____ in matrix; chondrocytes in lacunae Absorbs ____ Example: intervertebral discs
Parallel collagen fibers in matrix; chondrocytes in lacunae Absorbs shock Example: intervertebral discs
102
Bone Two-thirds of bone’s weight is ___; one-third is ___ Organic parts provide ___ Inorganic parts provide ____
Two-thirds of bone’s weight is inorganic (mostly calcium salts); one-third is organic (collagen and other proteins) Organic parts provide flexibility Inorganic parts provide compressional strength
103
bone Periosteum: Mature bone cells are called ___
Periosteum: dense irregular connective tissue covering Mature bone cells are called osteocytes
104
Two forms of bone:
Compact bone is arranged in cylindrical osteons of concentric lamellae Spaces within spongy bone house hemopoietic cells that generate blood cells
105
Compact bone Calcified matrix organized in ___ Protects ___, provides ___ for ___, stores ___ Example: bones of body
Calcified matrix organized in osteons Protects organs, provides levers for movement, stores calcium Example: bones of body
106
Fluid Connective Tissue Fluid connective tissue refers to...
Fluid connective tissue refers to blood and lymph
107
Blood consists of:
Blood consists of: Plasma: A watery ground substance containing protein fibers Erythrocytes: Red blood cells Leukocytes: White blood cells Platelets: Fragments of blood cells involved in blood clotting
108
Lymph is derived from ____—has no formed elements
Lymph is derived from plasma—has no formed elements
109
Blood Contains __, ___, & ___ Transports ... governs... Found in...
Contains blood cells, platelets, and plasma Transports respiratory gases, nutrients, wastes, hormones; governs immune response Found in heart and in blood vessels throughout body
110
body membranes do what?
Membranes line the major body cavities and cover organ surfaces
111
body membranes
1. Mucous membranes line passages that open to external environment 2. Serous membranes (e.g., pericardium) have two layers (parietal and visceral) and secrete friction-reducing fluid between them 3. Cutaneous membrane is the skin (epidermis and dermis) 4. Synovial membranes line the cavities of some joints and secrete friction reducing fluid there
112
Tissue change and aging Tissues often undergo changes in--- & ___with aging Epithelia thin, connective tissues lose ___ Repair processes lose ___
Tissues often undergo changes in structure and chemical composition with aging Epithelia thin, connective tissues lose pliability Repair processes lose efficiency
113
aging tissue Metaplasia: Epithelia lining respiratory airways of people who smoke change from ___ to ___ Hypertrophy: An increase in the ____of existing cells Hyperplasia: An increase in ____ in a tissue Neoplasia: _____, which forms a tumor Atrophy: _____ of tissue by cell size or number
Metaplasia: Epithelia lining respiratory airways of people who smoke change from pseudostratified ciliated to stratified squamous Hypertrophy: An increase in the size of existing cells Hyperplasia: An increase in number of cells in a tissue Neoplasia: Out-of-control growth, which forms a tumor Atrophy: Shrinkage of tissue by cell size or number