Chapter 5 Flashcards
exocrine glands
release enzymes to the external environment through ducts- include sweat, oil, mucous and digestive glands
endocrine glands
release hormones directly into body fluids
receptors
hormones act by binding to proteins called _____
peptide hormones
derived from hormones, made in the rough ER then transferred to Golgi appartus where it is modified with carbohydrates to become its final form
effector
target cell of the hormone
how peptide hormones diffuse into the cell membrane of the effector
attach to a membrane bound receptor,
intracellular second messenger
cAMP, cGMP or calmodulin –> activates/deactivates enzymes and/or ion channels, cascade of chemical reactions
AP hormones
FSH, LH, ACTH, hGH, TSH, prolactin
PP hormones
ADH, oxytocin
Parathyroid hormones
PTH
Pancreatic hormones
glucagon, insulin
steroid hormones
derived from cholesterol, require a protein transport molecule to dissolve in the blood stream, diffuse through the cell membrane of the effector, combine with a receptor in the cytosol, receptor transports the steroid into the nucleus and the steroid acts at transcription level, formed in the smooth ER and in the mitochondria
steroid hormones list
cortisol, aldosterone, estrogen, progesterone, tesosterone
tyrosine derivative hormones list
T3 and T4, catecholamines (epinephrine and nrepinephrine)
tyrosine derivative hormones
formed by enzymes in the cytosols or on the rough ER, slowly released to their target tissues and bind to receptors inside the nucelus, latent period to their response, increase the durate of their effect
anterior pituitary and hypothalamus
hypothalamus controls the release of AP hormones
hGH
peiptide, growth in almost all cells in the body, increase cell size, protein sythesis, mobilizing fat sores, increasing use of FA for energy, decrease use of glucose, increase translation and transcription
ACTH
peptide, stimulate adernal cortex to release glucocorticoids via 2nd messenger system using cAMP, released is stimulated by many types of stress
TSH
stimulate release of T3 and T4 via second messenger system using cAMP, increases thyroid cell size, number and rate of secretion of T3 and T4; T3 and TA have negative feedback effect on TSH release
prolactin
promotes milk production, inhibts menstrual cycle, suckling stimulates hypothalamus to stimulate AP to release prolactin
oxytocin
increase uterine contractions during pregnancy and causes milk to be ejected from the breasts
ADH
aka vasopressin, causes collecting ducts of kidney to become permeable to water, reducing the amount of urine and concentrating urine, increases blood pressure, coffee and beer are ADH blockers
posterior pituitary
hormones are synthesized in the neural cell bodies of the hypothalamus
adernal cortex
mineral corticoids and glucocorticoids