Chapter 5 - Antibiotics and Contaminants Flashcards

(44 cards)

1
Q

MRSA

A

Methicillin Resistant Staphylococcus Aureus

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2
Q

two types of MRSA

A

CA-MRSA: community aquired
HA-MRSA: hospital acquired

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3
Q

major classes of antibiotics

A
  • aminoglycosides
  • beta-lactams
  • tetracyclines
  • glycopeptides
  • macrolides
  • sulfonamides
  • ionophores
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4
Q

WWTPs

A

Waste Water Treatment Plants

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5
Q

What type of treatment includes solids settling and screening?

A

primary

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6
Q

What type of treatment includes activated sludge, rotating biological contractors, and aerated lagoons?

A

secondary

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7
Q

What type of treatment includes sand filtering or lagoons, and disinfection via chlorine or ozonation?

A

tertiary

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8
Q

Antibiotic removal is most effective at removing what class of antibiotic?

A

tetracyclines

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9
Q

Antibiotic removal is least effective at removing what class of antibiotics?

A

sulfamides

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10
Q

What is the most effective secondary treatment?

A

activated sludge

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11
Q

Which two antibiotics can be removed efficiently abiotically?

A
  • tetracycline
  • ciprofloxacin
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12
Q

genes for aminoglycoside resistance

A

numerous

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13
Q

genes for beta-lactam resistance

A

Bl2A-1

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14
Q

genes for MLSb resistance (microlides)

A

ErmA-H

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15
Q

genes for Multidrug transporters

A

Emr4

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16
Q

genes for tetracycline resistance

A

Tet^a-l
Tet^m,o,q,t,w
Tet^x

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17
Q

genes for sulfonamide resistance

A

Sul1-3

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18
Q

genes for glycopeptide resistance

19
Q

modes of resistance for Bl2A-1

A

creates beta-lactamase that breaks ring open

20
Q

modes of resistance for ErmA-H

A

post-transcriptional methylation of the 23S ribosomal subunit

21
Q

modes of resistance for Emr4

A

multi-drug effix pump

22
Q

modes of resistance for Tet^a-l

23
Q

modes of resistance for Tet^m,o,q,t,w

A

ribosomal protection protein

24
Q

modes of resistance for Tet^x

A

oxioreductase, modifes tetracycline

25
modes of resistance for Sul1-3
dihydroperoate synthase reisstant to inhibition
26
modes of resistance for vanA-G
reisistant operon genes
27
what is the range for excretion rates for hosehold wastes?
10%-95% | most have rates over 50%
28
includes an anaerobic settling tank and some sort of dispersion into the vadose zone of soil
septic systems
29
what kind of septic systems may improve the treatment of sulfamides
cluster sytems
30
how is poultry manure treated and stored?
manure mixed with sawdust or other organic bedding and kept in dry stacks
31
how is dairy manure treated and stored?
sand bedding, semi-solid manure, drained into settling basin
32
how is beef manure treated and stored?
feedlots with runoff, flow into retention ponds or lagoons
33
how is swine manure treated and stored?
underground holding basins and stored in lagoons
34
what are lagoons?
treat tetracycline and sulfamides stay in aqueous phase
35
what are sequencing batch reactors?
incorporate anaerobic treatment stage, aerobic treatment, and solids settling stage nearly completely treatm antibiotics and allow for capture of methane
36
what can be added to sequencing batch reactors which results in the addition removal and treatment including bacteria?
Fenton's reagent (Fe and H2O2)
37
where are antibiotics found in high levels in solids?
digestive system
38
where are antibiotics found in high levels in the water column?
livestock lagoons
39
antibiotic levels don't always correlate with the amount of antibiotic resistant genes (ARGs)
40
what are some environmental factors that do correlate with ARGs?
lead ammonia
41
What is lead's R value which allows it to correlate with ARGs?
R = 0.75
42
What is ammonia's R value which allows it to correlate with ARGs?
R = 0.69
43
What is the total N R value which allows it to correlate with ARGs?
R = 0.68
44
What is the R value for total dissolved solids?
R^2 > 0.9 | Barkovskii