Chapter 5 Membrane Structures, Synthesis And Transport Flashcards

(36 cards)

1
Q

Phospholipid bilayer

A

The framework of the two membrane
Consists of two layers of phospholipids
Are amphipathic

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2
Q

Lipid raft

A

A group of lipids that float together as a unit within a larger sea of lipids

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3
Q

Passive Transport

A

The transport of a substance across a membrane that does not require an import energy.

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4
Q

Active Transport

A

Move a substance from an area of low concentration to one of high concentration with the aid of a transport protein. active transport requires an input of energy from a source such as ATP

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5
Q

What can go through artificial bilayer

A

Gases, very small, uncharged molecules, ethanol, water and urea

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6
Q

Simple diffusion

A

Occurs when a substance moves from region of high concentration to a region of lower concentration

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7
Q

Facilitated diffusion

A

A transport protein provides a passageway for a substance to diffuse across a membrane

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8
Q

Fluid-mosaic model

A

Plasma membrane is a semi fluid phospholipid by layer with a mosaic of proteins

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9
Q

Leaflet

A

Half of a phospholipid bilayer

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10
Q

Lipid transfer: Scramblases

A

From protein channel between leaflets for lipids to transfer down a concentration gradient no ATP

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11
Q

Flippase

A

Move lipids from the outer to inner leaflet using ATP

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12
Q

Floppase

A

Move lipids from the inner to outer leaflet using ATP

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13
Q

Bilayer fluidity

A

Optimal level of bilayer fluidity is essential for normal cell function, growth, and division
Membranes are less fluid at low temperatures
Organisms can alter lipid composition to ensure optimal fluidity

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14
Q

Transmembrane proteins

A

Spans from one side of the membrane, through the hydrophobic interior, to the other side of the bilayer

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15
Q

Lipid anchored protein

A

Covalent attachment of a lipid to an amino acid side chain within the protein anchors the protein to the membrane by inserting into the bilayer

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16
Q

Estimated percentage of membrane proteins is substantial

A

29%-30% of all genes may encode membrane proteins

17
Q

Membrane are important medically as

A

Approximately 70% of medications exert effects by binding to the membrane proteins
Example anti-histamine, which bind to histamine receptors in cell membrane

18
Q

Glycosylation

A

Process of covalently attaching a carbohydrate to a protein or lipid

19
Q

Isotonic

A

equal water and solute concentrations on both sides of the membrane

20
Q

Ligand-grated channels

A

Open in response to binding of an extra cellular ligand

21
Q

Voltage gated channels

A

Open and close in response to electrical gradients

22
Q

Mechanosensitive channels

A

Are sensitive to changes in membrane tension

23
Q

Aquaporin

A

CHIP28
Hypothesized that this protein may function as a water channel
Allows facilitated diffusion of water across the membrane

24
Q

Transporters

A

Slower than channels

For transport to occur, salute Binds in a hydrophilic pocket exposed to one side of the membrane

25
Uniporter
Bind a single molecule or ion and transported across the membrane
26
Symporters
Bind two or more different types of ions or molecules and transport them in the same direction
27
Anti porters
Binds two or more different types of ions or molecules and transport them in opposite directions
28
ATP driven pumps
Hydrolyze ATP to actively transport solutes against a gradient
29
Plasma membrane
Bromembrane that separates the internal contents of a cell from its external environment
30
Function of cellular membranes
Protein sorting Cell signalling Anchoring Cell division
31
Carbohydrates attached to the cell surface serve two main functions
Cell protection and identification
32
How glycogen attaches to carbohydrates
Covalently
33
Hypertonic
Solution higher solute concentration outside the cell
34
Hypotonic
Lower solute concentration outside the cell
35
Turgor pressure
The internal water pressure generated in plant cells as cell membrane presses on the cell wall
36
Channels
Transmembrane proteins that form a passageway fir the facilitated diffusion of ions or molecules across the membrane Most channels are gated