Chapter 5 - The Integumentary System Flashcards
(88 cards)
Integumentary System
Composed of skin, hair, oil, sweat glands, nails and sensory receptors. Temperature, Protection, Sensory.
Skin or cutaneous membrane
AKA Cutaneous Membrane, largest organ
Epidermis
Superifical, Avascular
Dermis
Connective tissue, Vascular
Subcutaneous layer or hypodermis
In the dermis, consists of areolar and adipose tissues. Fibers that extend from dermis anchor the skin to the subQ layer, attaching to fascia. Storage for fat, has large blood vessels.
Lamellated corpuscle or pacinian corpuscle
subQ contains these nerve endings that are sensitive to pressure.
Keratinocyte
90% of epidermis cells. Arranged in 4or5 layers to produce protein. Also produce lamellar granules
Keratin
Protein, tough, fibrous to protect.
Melanocyte
8% of epidermis cells. Produce pigment, transfer melanin granules to keratinocytes.
Melanin
Yellow-red or brown-black. Absorbs UV, protective veil over nucleus.
Intraepidermal Macrophages / Langerhans Cell
From red bone marrow to epidermal cells. Immune responses, easily damaged by UV.
Tactile Epithelial Cells or Merkel Cell
least numerous. Deepest layer of epidermis contact disks for touch.
Tactile Disk or Merkel Disk
Flattened process of a sensory neuron for touch.
Thin and Thick skin
Thin=four strata and thin stratum corneum.
Thick=where exposure to friction is greatest, five strata and thick stratum corneum.
stratum basale or stratum germinativum
Deepest layer of epidermis. Single row of cuboidal or columnar keratinocytes, some are stem cells.
keratin intermediate filaments (tonofilaments)
The cytoskeleton within keratinocytes include these, to form keratin.
Stratum Spinosum
- 8-10 layers of keratinocytes. Coarser bundles of keratin. Have spinelike projections which insert into desmosome to joins cells together for strength and flexibility.
Stratum Granulosum
Middle. 3-5 layers. Apoptosis. Keratinocytes carry on vital metabolic reactions. (transition layer)
Keratohyalin
Dark staining granules, assembles keratin intermediate filaments into keratin.
Lamellar Granules
Inside keratinocytes are membrane enclosed lamellar granules- fuse with the plasma membrane and release a lipid-rich secretion. (water-repellant)
Stratum Lucidum
Only in thick skin. 4-6 layers.
Stratum Corneum
25-30 layers, no nuecleus or organeles. Cells overlap, continuously shed
Callus
Constant exposure of skin to friction stimulates increased cell production and keratin production that results in the formation of a callus, an abnormal thickening of the stratum corneum.
Keratinization
As cells move from one epidermal layer to the next they accumulate more and more keratin.