Chapter 6 Terms Flashcards

Hematology

1
Q

plasma

A

the bulk of blood, contains nutrients, substances made by the liver / glands, waste products, and is made of 90% water

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2
Q

albumin

A

a protein that keeps water from seeping out of the blood and into tissues

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3
Q

electrolytes

A

elements containing an ionic (pos/neg) charge which regulate various cardiovascular functions

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4
Q

hematopoiesis

A

process where all formed elements of the blood develop in the red marrow of long / flat bones.

hemat/o-: blood

-poiesis: process of creating

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5
Q

erythrocyte

A

a name for red blood cells (RBC). they are red due to hemoglobin, an iron-containing molecule.

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6
Q

hemoglobin

A

an iron-containing molecule which binds to and carries oxygen away from lungs and carbon dioxide to the lungs.

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7
Q

how are erythrocytes formed?

A

Stem cells in the red bone marrow form into erythroblasts, which turn into normablasts, which turn into reticulocytes, and lastly become erythrocytes.

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8
Q

leukocytes

A

white blood cell (WBC), which includes 5 types of cells

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9
Q

what are the 5 types of leukocytes?

A
  1. neutrophils
  2. eosinophils
  3. basophils
  4. lymphocytes
  5. monocytes
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10
Q

granulocyte

A

a type of WBC that has little granules inside of it, 3 of the 5 types of WBC are these

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11
Q

agranulocyte

A

a type of WBC that lacks granules inside of it, 2 out of 5 WBC types are these

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12
Q

neutrophil

A

a granulocyte. engulfs and destroys bacteria.

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13
Q

eosinophil

A

a granulocyte. it releases chemicals to destroy foreign cells, such as dust

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14
Q

basophil

A

a granulocyte. releases histamine at the site of an injury, and heparin to control clot size

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15
Q

lymphocytes

A

an agranulocyte. they produce antibodies, which are toxic granules to destroy infected cells. there are multiple types.

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16
Q

NK (natural killer) cells

A

a lymphocyte which recognizes a cancer cell or virus and kills it

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17
Q

B cell

A

a lymphocyte which is inactive until a monocyte gives it a pathogen fragment

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18
Q

T cells

A

a group of lymphocytes that mature in the thymus, with 4 types

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19
Q

cytotoxic T cell

A

a lymphocyte that produces toxic granules to kill infections

20
Q

helper T cells

A

a lymphocyte that produces interleukin and stimulates the production of cytotoxic T cells

21
Q

memory T cells

A

a lymphocyte that remembers a pathogen after helper T cell exposure and becomes a cytotoxic T cell when it returns.

aka CD4.

22
Q

suppressor T cells

A

a lymphocyte that limits the immune response by inhibiting B/T cells.

aka CD8.

23
Q

thrombocyte

A

platelets - cell fragments that aid in the blood clotting process

stem cell => megakaryoblast => megakaryocyte => platelet

24
Q

blood type

A

varies based on the presence of 3 antigens on a RBC: A, B, A+B, or O, as well as the Rh factor (+ or -).

25
how does a clot form?
1. Platelet aggregation: thrombocytes stick to an injured blood vessel wall and clump. 2. Platelets then release clotting factors 3. The clotting factors are also released from plastma which makes fibrin. 4. Fibrin holds the RBC and forms the clot (thrombus) 5. Clot size is limited by basophil releasing heparin
26
what are the 12 clotting factors?
From I to XIII (there is no VI) I. fibrinogen - liver II. prothrombin - liver III. tissue factor (thromboplastin) - injured tissue IV. calcium - platelets V. prothrombin accelerator - liver VII. prothrombin conversion accelerator - liver VIII. antihemophilic factor - platelets IX. plastma thromboplastin factor - liver X. Stuart-Prower factor - liver XI. plastma thromboplastin antecedent - liver XII. Hageman factor - liver XIII. fibrin-stabilizing factor - liver + platelets
27
hemostasis
the cessation of bleeding
28
interleukin
stimulates b cells, t cells, and NK cells; also the cause of fever (temp = leukocyte activity)
29
interferon
stimulates other cells to produce antivirals
30
tumor necrosis factor (TNF)
destroys bacterial endotoxins as well as cancer
31
immunoglobulins (antibodies)
coat the outside of bacteria/viruses/cancer to mark for destruction. complement proteins (C1-C9) attach to them and drill holls into organisms to destroy them.
32
IgA
antibody type that gives passive immunity, it is in bodily secretions and the skin surface
33
IgD
an antibody - on the surface of B cells and activates them into a plasma cell
34
IgE
an antibody - surface of basophils, causes release of histamine / heparin
35
IgG
an antibody - active immunity, reacts to what it has seen before
36
IgM
an antibody - produced 1st time body encounters a pathogen; they are big in size
37
blood dyscrasia
any disease involving blood cells
38
hemorrhage
loss of a large quantity of blood
39
pancytopenia
decrease of all blood cell types, due to a fail in stem cell production
40
septicemia
severe infection spread to the blood; aka sepsis
41
abnormal red blood cell morphology
any type of abnormality in the shape size or color of RBC
42
anemia
a decrease in # of erythrocytes by varying causes (5 sub-types)
43
aplastic anemia
failure of bone marrow to produce RBC, but they are normocytic and normochromic
44
normocytic
normal in size
45
normochromic
normal in color
46
folic acid deficiency
malnourishment, common in pregnant women. RBC are abnormally large (macrocytic)
47
iron deficiency
poor diet, menstruation, blood loss. RBC are microcytic (small) and hypochromic (pale)