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Question 1

20kg animal (what re-breathing bag size)

Answer 1

2L

Question 2

30kg animal (what re-breathing bag size)

Answer 2

3L

Question 3

50kg animal (what re-breathing bag size)

Answer 3

5L

Question 4

Calculation of therapeutic index

Answer 4

LD50/ED50

Question 5

Xray

Answer 5

Advantages: fine resolution of hard surfaces; fast Disadvantages: less detail soft structures; radiation hazard

Question 6

CT

Answer 6

Advantages: detail soft structures; lesions in 3D Disadvantages: radiation exposure risk

Question 7

PET/SPECT

Answer 7

Advantages: image in vivo processes; high resolution soft tissue Disadvantage: requires short half-life radioisotopes; radiation risk

Question 8

Ultrasound

Answer 8

Advantages: soft tissue abnormalities; may be used intravascularly Disadvantages: poor image quality; not quantifiable

Question 9

Thermography

Answer 9

Advantages: non invasive, repeatable and quantifiable Disadvantages: low resolution; may be affected by environmental temperatures and animal factors

Question 10

MRI

Answer 10

Advantages: good contrast and tissue distinction; no radiation Disadvantages: restrictive condition; metal safety hazards

Question 11

Fluorescent imaging

Answer 11

Advantages: can track metabolic processes Disadvantages: time sensitive and requires chlorophyll free diet

Question 12

Bioluinescence

Answer 12

Advantages: noninvasive; fast and high throughput imaging Disadvantages: requires genetic manipulation of animals; not quantifiable

Question 13

Red blood tube stopper

Answer 13

no anticoagulant; serum

Question 14

Lavender/purple blood tube stopper

Answer 14

EDTA; plasma

Question 15

Light green blood tube stopper

Answer 15

heparin, plasma

Question 16

Enteropathy

Answer 16

NHP; Bacterial

Question 17

Life cycle of tapeworm Dipylidium caninum

Answer 17

Question 18

Live cycle of liver fluke

Answer 18

Question 19

Isograft (I)

Answer 19

a graft of tissue that is obtained from a donor geneticially identical to the recipient

Question 20

allograft

Answer 20

a transplant from one individual to another of the same species with a different genotype

Question 21

xenograft

Answer 21

a transplant from one species to a different species

Question 22

nude mouse

Answer 22

lack of a thymus; does not produce t cells

Question 23

SCID mouse

Answer 23

lacks both T and B cells

Question 24

XID mouse

Answer 24

B cells are defective and some llneage B cells are missing altogether

Question 25

Beige mouse

Answer 25

defective NK cells

Question 26

Phases of antibody production

Answer 26

Lag, Log, Plateau, Decline

Question 27

IgG

Answer 27

most abundant immunoglobulin in serum

Question 28

IgM

Answer 28

Second most abundant type of serum antibodies Also present in birds, reptiles, amphibians, fish

Question 29

IgA

Answer 29

found in body screations

Question 30

location of lymph nodes in the mouse

Answer 30

Question 31

Dry Bulb Macro Temp Mouse, rat, hamster, gerbil, guinea pig

Answer 31

20-26C

Question 32

Dry Bulb Macro Temp Rabbit

Answer 32

16-22C

Question 33

Dry Bulb Macro Temp Cat, dog, NHP

Answer 33

64-84 18-29C

Question 34

Dry Bulb Macro Temp Farm animals, poultry

Answer 34

61-81 16-27C

Question 35

Which factor will has the greatest effect on the amount of dissolved oxygen in water?

Answer 35

temperature

Question 36

What is the average life span of the rat?

Answer 36

2.5 to 3 years

Question 37

Female rats usually have postpartum estrus within ____ hours of parturition.

Answer 37

48

Question 38

An unusual behavior that may be noticed in approximately 20% of gerbils is:

Answer 38

seizures

Question 39

The average life span of a gerbil is:

Answer 39

2-4 years

Question 40

Which species is most likely to be used to study thermoregulation in the laboratory?

Answer 40

bats

Question 41

What seasonal change does an adult ferret undergo?

Answer 41

Losing weight in the spring/summer during mating season and gaining weight back in the fall

Question 42

What is a characteristic of Old World monkeys?

Answer 42

Short nose with downward pointing nostrils

Question 43

What is the term for a neutered male sheep?

Answer 43

wether

Question 44

Minimum space Mice

Answer 44

Area 6-15 square inches Height 5 inches

Question 45

Minimum space Rats

Answer 45

Area 17-70 square inches Height 7 inches

Question 46

Minimum space Hamsters

Answer 46

Area 10-19 square inches Height 6 inches

Question 47

Minimum space Guinea pigs

Answer 47

Area 60-101 square inches Height 7 inches

Question 48

Rabbit cage height

Answer 48

16 inches

Question 49

Cat cage height

Answer 49

24 inches

Question 50

what is not included in a study protocol?

Answer 50

the conclusions of the study

Question 51

carcass fridge temperature

Answer 51

below 44.6F

Question 52

Dog minimum floor space

Answer 52

To Calculate the minimum amount of floor space: Measure the length of the dog in inches (from the tip of its nose to the base of its tail). Add 6 inches to this length. Square this sum (that is, multiply the above result by the same number). Then divide the squared result by 144 to obtain the minimum amount of floor space in square feet. The minimum interior height must be at least 6 inches higher than the head of the tallest dog in the enclosure when it is in a normal standing position.

Question 53

According to the Guide, how often must the IACUC conduct the facility inspections and program review?

Answer 53

annually (whereas PHS requires every 6 months)

Question 54

According to the PHS policy, IACUC-approved research projects must be reviewed how often?

Answer 54

every 3 years

Question 55

How often does an institution need to resubmit an Animal Welfare Assurance if with PHS?

Answer 55

every 5 years