Childhood disease III Flashcards Preview

Real Path Exam III > Childhood disease III > Flashcards

Flashcards in Childhood disease III Deck (12):
1

What type of transloaction results in infantile fibrosarcoma?

ETV6-TRKC gene via 12;15 transloaction.

2

What is a tumor marker for congenital infantile fibrosarcoma?

ETV6-TRKC

3

what is the incedence of teratoma?

1/20,000 - 40,000 live births

4

What is the most common solid tumor in the newborn?

acrococcygeal teratoma

5

What is the most common solid congenital malignancy?

Congenital neuroblastoma.

6

What oncogene is associated with neuroblastoma?

N-myc

7

Urine vanillylmandelic acid and homovanillic acid are markers for what condition?

Neuroblastoma.

8

"Small blue round cells with rosette structure and dense core neurosecretory granules"

Neuroblastoma

9

What is most common primary malignant tumor of kidney and what is its incidence?

Wilms tumor with an incidence of 1/10,000

10

Wilms tumor is associated with inactivation of what?

WT1 and WT2

11

Rhabdomyosarccoma

Tends to go to the neck and eyes
accounts for 5-8% malignancy

12

What type of rhabdomyosarcoma is most common?

Embryonal rhabdomyosarcoma 60% followed by:

Alveolar rhabdomyosarcoma
and
Pleomorphic rhabdomyosarcoma (worst)