Chronic Kidney Disease Flashcards

(30 cards)

1
Q

how long must kidney damage or decreased kidney function be present for before it is diagnosed CKD

A

3 months

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2
Q

what is normal GFR

A

90-120ml/min

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3
Q

when will creatinine be raised

A

when 60% of total kidney function is lost

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4
Q

what category of people have a normally raised serum creatinine

A

african americans, because of higher muscle mass

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5
Q

where does creatinine come from

A

muscle breakdown

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6
Q

what can you estimate from serum creatinine

A

GFR - there is a relationship

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7
Q

what additional information is necessary to calculate eGFR from serum creatinine

A

age, weight, gender, race

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8
Q

CKD stages

A
by GFR levels
1 = >90
2 = 60-89
3a = 45-59
3b = 30-44
4 = 15-29
5 = <15
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9
Q

a GFR of 42 is what stage CKD

A

3b

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10
Q

what is the range of CKD stage 2

A

60-89

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11
Q

what stage of CKD is a GFR of 19

A

stage 4

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12
Q

test to check blood and protein in urine

A

dipstick test

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13
Q

3 approaches to assessing kidney function

A

what they manage to excrete
what they manage to keep in
the anatomy of the kidneys

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14
Q

definition of CKD

A

proteinuria, haematuria, abnormal x-ray findings or GFR<60 for >30 months

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15
Q

cost of dialysis per year per patient

A

£35,000

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16
Q

prevalence of CKD

A

8-12% with up to 50% in >70

17
Q

most common causes of CKD

A

diabetes and hypertension

18
Q

5 key causes of CKD

A

diabetes, hypertension, glomerulonephritis, renovascular disease, polycystic kidney disease

19
Q

what surgery might you want to do in someone with a declining GFR

A

arteriovenous fistula - in preparation for dialysis

20
Q

4 approaches of CKD management

A
  1. treat underlying cause
  2. slow the rate of renal decline
  3. prevent complications
  4. prepare for RRT
21
Q

CKD blood investigations

A
urea, creatinine, electrolytes
bicarbonate
proteub
LFT
Ig
FBC
just basically assessing funciton and looking for cause
22
Q

CKD urine investigations

A

urinalysis dipstick
protein:creatinine ratio
24 hour urine collection

23
Q

CKD imaging

A

X-ray

ultrasound (good for showing calyxes)

24
Q

other CKD investigations

25
how do you slow the rate of renal decline
controlling BP and proteinuria, and treat underlying cause
26
from BMJ what are the 1st investigations to order in CKD
``` serum creatinine urinalysis urine microalbumin renal ultrasound eGFR ```
27
alphabet of CKD complications
``` Acidosis/Anaemia Bone disease CV risk Death and Dialysis Electrolytes Fluid Overload Gout Hypertension ```
28
how can you remember the complications of CKD
just think about the functions of a healthy kidney and what will lack in reduced function and sure that alphabet thing but it's pish
29
if somebody has hyperparathyroidism and CKD what specific treatment will they need
cinacalcet (mimics action fo calcium) and an active vit D analogue (calcitriol)
30
what is the primary treatment of CKD below stage 4/5
BP control