Chronic Pancreatitis Flashcards Preview

Conditions: GI > Chronic Pancreatitis > Flashcards

Flashcards in Chronic Pancreatitis Deck (14):
1

Causes of chronic pancreatitis?

Alcohol

CF

Annular pancreas

Hypercalcaemia

2

Pathology of chronic pancreatitis?

Continuing inflammation of the pancreas resulting in

IRREVERSIBLE

glandular destruction

3

Symptoms?

Diabetes

Weight loss and anorexia
- Lack of protein absorption

Jaundice

Pancreatic pseudocysts

Epigastric pain

4

Signs?

Significant steatorrhoea
- Exocrine insufficiency

5

What is a pancreatic pseudocyst?

A collection of fluid filled with digestive enzymes in the omenta bursa

6

Investigations of chronic pancreatitis?

Plain AxR

USS

EUS

Bloods

Pancreatic function tests
- Lundh
- Pancreolauryl

7

What is the lundh test?

An endoscope is used to extract pancreatic digestive juices and test them?

8

What is the pancreolauryl test?

Give fluorescin dilaurate as a liquid
- This is normally broken down by cholesterol ester hydrolase

In pancreatic insufficiency it will be detected in the urine in high quantities

9

Blood test results?

High amylase in acute exacerbations

Low albumin

LFTs all up

INR raised

10

Treatment if cause is blockage?

Endoscopic treatment

11

What can be done if the pancreatitis is very advanced?

Total pancreatectomy
- APICT

12

Palliative treatment?

Opiates
Coeliac plexus block
Enzyme supplements

13

Complications?

Pancreatic cancer

14

What is APICT?

New treatment not in our lectures

Islets are removed and transplanted into the liver

Pancreatectomy then performed and islets can successfully still produce insulin and glucagon

Successful short term