Primary Sclerosing Cholangitis Flashcards Preview

Conditions: GI > Primary Sclerosing Cholangitis > Flashcards

Flashcards in Primary Sclerosing Cholangitis Deck (10):
1

What is primary sclerosing cholangitis?

Inflammation, fibrosis and strictures of the intra and extra hepatic bile ducts

2

What causes primary sclerosing cholangitis?

Unknown

3

What are the symptoms of PSC?

Liver failure from chronic biliary obstruction and cirrhosis late stage

Asymptomatic early stage

Painless obstructive jaundice
- Pruritis

4

Signs?

Hepatomegaly
Splenomegaly

5

Tests?

Bloods
- FBC
- LFTs

ERCP/MRCP

6

What is shown on ERCP?

Strictured biliary tree

7

LFT results?

Alk Phos up
Bilirubin up

8

Surgical treatment?

Cholecystectomy

Liver transplant in late disease

9

Pharma treatment?

Pruritis - colestyramine

Cholestasis
- Ursodeoxycolic acid

Antibiotics for bacterial cholangitis

10

What does PSC increase your chances of?

Cholangiocarcinoma