Clinical Case Discussion of Antimicrobial Selection Flashcards Preview

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Flashcards in Clinical Case Discussion of Antimicrobial Selection Deck (11)
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1


First step in AB selection?

 

  • ID specific site - Localize the source, first step in defining spectra

2


What determines the microbial spectrum?


The site of infection

3


What should be considered when determining a microbial spectrum?

 

  • Host comorbidity (HIV)
  • Resistance

4


Considerations when determining drug route?

 

  • Severity
  • Site
  • Pharmacokinetics
  • Host Immunity

5

What should be considered when assessing drug benefit/toxicity?

 

  • Host immunity
  • Host PMHx
  • Host comorbidity

6

What are empirical AB selection principles driven by?

 

  • Likelihood of resistance
  • Severity of illness

7


What drives definitive selection of AB?

 

  • Culture results

8


In a patient with adrenal insufficiency, why would a fever be observed?


Taking the patient off steroids results in fever

9


What are the most likely bugs to cause infection of skin?

 

  • Staphylococcus aureus
  • Streptococcus

10


When considering a possible staph infection, what important consideration should be made?


Is it methicillin resistant or not? (MRSA vs. MSSA)

11


If staphylococcus aureus infection is ID'ed, what is the plan?


Use IV ABs because of the potential of endocarditis