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1

What questions should be asked to any patient with suspected psoriasis?

if theyve had any problems with their scalp or joint pain or nails

2

What might be seen on examination of the nails of a patient with psoriasis?

pitting; onycholysis; subungal hyperkeratosis; dystrophy

3

What does guttate psoriasis look like?

small, red/salmon pink papules on the skin with scales

4

What often precipitates guttate psoriasis?

strep throat infection

5

What is the auspitz sign?

removal of surface scale reveals tiny bleeding points

6

What is auspitz sign caused by pathologically?

dilated capillaries in elongated dermal papillae

7

What are the 4 main types of psoriasis?

chronic plaque psoriasis (psoriasis vulgaris)
guttate psoriasis
palmoplantar pustular
erythrodermic/ widespread pustular

8

What other diseases are psoriasis patients at risk of?

cardiovascular risk is increased

9

Why are lifestyle questions important in psoriasis?

as CVS risk is increased, risk factors need to be managed

10

What are the topical therapies available for psoriasis?

vitamin D analogues
coal tar
dithranol
steroid ointments
emollients

11

What are the actions of emollients?

anti-inflammatory
anti-hyperkeratotic

12

What other treatments are there for psoriasis?

phototherapy
immunosppression
immune modulation (anti-TNFalpha)

13

What is the pathogenesis of acne?

poral occlusion
bacterial colonisation of duct (p. acnes)
dermal inflammation
increased sebum production

14

What is the morphology of acne?

comedones
pustules and papules
cysts
erythema

15

What are the topical treatments available for acen?

benzoyl peroxide
topical vit A derivatives
topical antibiotics

16

What are the systemic treatments available for acne?

antibiotics
isotretinoin

17

Why are there no comedones found in rosacea

rosacea is not a disease of the pilosebaceous unit

18

Aside from facial effects, what else can be caused by rosacea?

conjuctivitis/gritty eyes

19

What are the topical therapies available for rosacea?

metronidazole
ivermectin

20

What are the systemic therapies available for rosacea?

tetracycline
isotretinoin

21

What are Wickham's striae?

whitish lines seen in the papules of lichen planus and in the buccal mucosa

22

What drugs can cuase lichenoid drug eruptions?

ACEI; statins

23

How is lichen planus treated?

topical steroid

24

What areas does lichen planus typically effect?

volar wrists/forearms, shins and snkles

25

What is the difference between bullous pemphigoid and pemphigus?

pemphigoiD- split is Deeper through DEJ
pemphiguS-split more Superficial, intra-epidermal

26

What is Nikolsky's sign?

top layers of the skin slip away from the lower layers when slightly rubbed

27

What does Nikolsky's sign indicate?

plane of cleavage is within the epidermis

28

What age of patient is bullous pemphigoid seen in?

elderly patients

29

Where is bullous pemphigoid seen on the body?

localised to one area or widespread on the trunk and proximal limbs

30

What is seen early in the disease progression of bullous pemphigoid?

urticated itchy plaques