Pruritis Flashcards Preview

Dermatology > Pruritis > Flashcards

Flashcards in Pruritis Deck (7)
Loading flashcards...
1

What nerves carry the sensation of itch?

unmyelinated C fibres

2

What are some of the pre-formed mediators that mast cells release upon degranulation?

proteases
heparin
histamine
cytokine

3

What is a pruritoceptive cause of itch?

something (usually assoc, with inflam or dryness) in skin that triggers itch

4

What is a neuropathic cause of itch?

damage of any sort to central or peripheral nerves causing itch

5

What is a a neurogenic cause of itch?

no evident damage in CNS but itch caused by e.g opiate effects on CNS receptors

6

What is a psychogenic cause of itch?

psychological cuase with no CNS damade

7

What are the treatments available for itch?

sedative anti-histamines (non-sedative AH only useful if histamine is part of mechanism)
amollients
antideressants
phototherapy
opiate antagonists (ondansteron)