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Basics of Focal Therapy Slidedeck > Clinical Knowledge > Flashcards

Clinical Knowledge Flashcards

1
Q

Tumor localized to prostate and not felt on DRE

A

T1

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2
Q

Tumor is localized and detectable on DRE

A

T2

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3
Q

Locally advnaced disease w extracapsular

A

T3

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4
Q

Cancer has advnaced to local strutures

A

T4

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5
Q

What is the PSA threshold for concern

A

4

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6
Q

Two types of BX

A
  1. transperineal2. transrectal
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7
Q

Gleason 6 risk

A

low

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8
Q

Immediate/favorable gleason

A

7 3+4

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9
Q

Intermediate/non-favorable

A

4 + 3

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10
Q

High Gleason Score

A

8

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11
Q

Very high Gleason

A

10-Sep

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12
Q

Describe targeted tissue after ablation

A

Fibrotic

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13
Q

Thickening of the rectal wall caused by abnormal heating

A

Symp[tomatic Edema

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14
Q

What does levels of “red” mean on Hausdoff Distance Scale

A

less similar

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15
Q

what does levels of “blue” mean on Hausdoff Distance Scale

A

More simular

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16
Q

MRI image that splits body between left/right vertical side view

A

longitudinal

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17
Q

MIR Image that devidesthe body from head to tail, horizontal plane from top down

A

transverse

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18
Q

Gland that produces seminal fluid

A

prostate

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19
Q

Prostate location 2

A
  1. behind pubis2. infront of rectum
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20
Q

PSA less than 10Gleason 6 or less ANDStage T1c/T2a

A

low rish

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21
Q

PSA between 10 and 20Gleason 7 ORT2b

A

Medium risk

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22
Q

DX PSA Greater than 20Gleason 8 ORT2c/T3

A

High Risk

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23
Q

used to predict the aggressiveness of cancer from BX

A

Genomic test

24
Q

Low Risk on Decipher Scale

A

0-.45

25
Q

High Risk on Decipher Scale

A

.6-1

26
Q

Identifies enlarged nodes or abnormalities

A

CT + PET

27
Q

Can detect evidence of spread to nodes and bones

A

MRI

28
Q

stageHalf or less of one glandMore than half of lobe but not both sidesCancer found in both lobes

A

T2

29
Q

stageCancer spread through capsule, not into the SVSpread to both sides

A

T3

30
Q

stageCancer found in bladder neck, external sphinxtor or rectumSpread to pelvic floor/wall

A

T4

31
Q

The lowest point narrow of prostate at sphincter

A

anatomyical apex

32
Q

Widest point of the prostate against the inferior surface of the bladder

A

base

33
Q

4 potential reasons for a high PSA and no cancer

A
  1. UTI2. Stimulation3. Exercise4. medication
34
Q

How much can the MRi underestimate tumor size

A

6-9 mm

35
Q

Active survallience patient type

A
  1. Low risk disease2. more t han 10 years to live3. Young and active
36
Q

T3b

A

SV inclusion

37
Q

T2c

A

Both sides of prostate have disease

38
Q

T2b

A

More than half, but not on both lobes

39
Q

T2a

A

Half or less one side

40
Q

T1c

A

Found on both lobes

41
Q

What does Gleason Score represent

A

Agressivness of disease

42
Q

Howq is the Gleason score determined from BX

A

Ranges 1-5 and dscribes how much disease is in each core

43
Q

What do pathologists look for when grading BX cores

A
  1. abnormal growth2. Uncontrolled Proliferation of cells
44
Q

Gleason 1

A

slow growing, non-aggressive cancer

45
Q

Gleason 2

A
  1. shows more space between glands2. slight irregularity3. slow growing
46
Q

Gleason 3

A

Intermediate forma of cancer, not aggressive

47
Q

FIrst number on Gleason represents

A

most prevelont form of cancer

48
Q

second Gleason number represents

A

Less prevelant form of cancer

49
Q

Gleason score for active survallience

A

less than 63 + 4

50
Q

Gleason score requiring immediate therapy

A

4+3 or above 8

51
Q

What does a 4K test measure

A

cancer aggressiveness

52
Q

Workflow for elevated PSA

A
  1. re-test2. MRI/4K test3. Targeted BX
53
Q

Used to optimize the size of ablative lesion, while perserving rectum and surrounding structures

A

HIFI parameters

54
Q

Tempature that destroys tissue C

A

80-95

55
Q

Walnut size gland that produces seminal fluid

A

Prostate

56
Q

What percentage of lesions are located in posterior prostate

A

80

Basics of Focal Therapy Slidedeck (12 decks)

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