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Flashcards in Clinical Use Deck (60):
1

Intraarticular for chronic pain resulting from permanent joint changes

Dexamethasone

2

parenteral iron

(a) Patients in whom GI absorption is prevented by disease (b) Patient who cannot tolerate orally administered iron (c) Hemodialysis patients (Sodium ferric gluconate and iron sucrose)

3

Effective against P. falciparum

Halofantrine

4

immunosuppressant for transplantation

tacrolimus

5

Gametocidal

Primaquine

6

cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP)

non-Hodgkin lymphoma

7

Primary and secondary prevention of thromboembolism in patients with nonvalvular atrial fibrillation

Dabigatran

8

used in pregnant patients with severe allergic reactions to heparin (e.g., HIT).

Fondaparinux and parenteral direct thrombin inhibitors

9

(a) Patients in whom GI absorption is prevented by disease (b) Patient who cannot tolerate orally administered iron (c) Hemodialysis patients (Sodium ferric gluconate and iron sucrose)

parenteral iron

10

Treatment and chemoprophylaxis of P. falciparum infections

"Atovaquone-proguanil aka Malarone"

11

standard prophylactic drug in SE Asia (in combination with mefloquine)

Doxycycline

12

fludarabine

CLL

13

circumvents the action of inhibitors of dihydrofolate reductase and potentiates the cytotoxic effects of 5- fluorouracil

Leucovorin (folinic acid)

14

DIC in patients where bleeding predominates

Fresh frozen plasma

15

eluting stents - Approved for coronary artery disease

sirolimus

16

Pneumocystis jiroveci: Prophylaxis for first-episode infection and therapy for pneumonia

Trimethoprim/sulfamethoxazole

17

von Willebrand disease (types 1 or 2A)

DDAVP (desmopressin)

18

Radical cure and terminal prophylaxis of infections with P. vivax and P. ovale; alternative chemoprophylaxis for all species

Primaquine

19

Infants usually receive an intramuscular injection at birth for VKDB prophylaxis

Phytonadione

20

Treatment (with quinine) of infections with P. falciparum

Doxycycline

21

Megaloblastic anemia

IM B12 and folic acid

22

Thromboprophylaxis in patients undergoing hip or knee replacement surgery

rivaroxaban

23

therapy of choice for many systemic fungal infections

Polyenes: Amphotericin B; followed by outpatient treatment with azoles

24

blood schizontocide

Artemisinin Chloroquine Mefloquine Doxycycline Quinine and Quinidine Sulfadoxine-pyrimethamine

25

Used only in combination with amphotericin B

flucytosine

26

autoimmune disease, e.g., autoimmune hemolytic anemia

MPA or MMF; (Mycophenolic Acid and Mycophenolate Mofetil)

27

Daclizumab and Basiliximab

Induction therapy for renal transplantation

28

Adequate for minor bleeding episodes in patients with mild hemophilia A

DDAVP (desmopressin)

29

used for prevention and acute treatment of VTE

heparin, LMWH, fondaparinux

30

Treatment and secondary prevention of VTE (DVT or pulmonary embolism)

rivaroxaban

31

patients with pernicious anemia or ileal disease

Cyanocobalamin (parenteral)

32

Tretinoin

APL

33

Drug of choice for treatment of P. falciparum-sensitive malaria & chemoprophylaxis of malaria

Chloroquine

34

DIC in patients where thrombosis predominates

Heparin

35

Immunosuppressants in patients with inflammatory bowel disease

azathioprine

36

used in patients with HIT to prevent further thromboembolic complications

Lepirudin and argatroban

37

Chemoprophylaxis and Treatment of infections with chloroquine‐resistant P. falciparum

Mefloquine

38

von Willebrand disease (types 2B, 2M, and 3)

Plasma-derived vWF-containing products

39

prophylactic administration when there is increased utilization such as in pregnancy and lactation

folate

40

Iron poisoning if plasma concentration of iron > 3.5 mg/L

Deferoxamine

41

Primary prophylaxis (regular replacement therapy) started at a young age before onset of joint bleeding in hemophilia A/B

Factor VIII/IX replacement Plasma-derived products; Recombinant factor VIII/IX

42

In patients with pernicious anemia high doses are used since it is absorbed via passive diffusion

Cyanocobalamin (oral)

43

High doses can control bleeding in acute bleeding episodes

Factor VIII/IX replacement Plasma-derived products; Recombinant factor VIII/IX

44

ABVD - doxorubicin [Adriamycin], bleomycin, vinblastine, and dacarbazine

Hodgkin lymphoma

45

First line therapies for P. falciparum malaria, especially cerebral malaria

Quinine and Quinidine

46

Treatment of acute bleeding episodes in patients with low inhibitor titer

Aminocaproic acid; Tranexamic acid

47

Therapy for meningitis caused by Cryptococcus neoformans

Amphotericin B + flucytosine followed by fluconazole

48

Active against hepatic-stage schizonts"

Primaquine "Atovaquone-proguanil aka Malarone"

49

Vitamin K deficiency

Phytonadione

50

imatinib

CML

51

Treatment of acute bleeding episodes in patients with high inhibitor titer

Prothrombin complex concentrate (PCC) and activated PCC (aPCC) OR Recombinant factor VIIa

52

Therapy for encephalitis cause by Toxoplasma gondii

Pyrimethamine/sulfadiazine

53

Treatment of infections with some chloroquine‐resistant P. falciparum; could be combined with artesunate; preventive therapy in endemic areas

Sulfadoxine-pyrimethamine

54

preferred for prevention and treatment of VTE in pregnancy

Low-molecular weight heparins (e.g., enoxaparin)

55

Available as a fixed dose combination with Artemether – 1st line therapy for uncomplicated malaria in most of Africa

Lumefantrine

56

Prophylaxis for first episode Toxoplasma gondii

Trimethoprim/sulfamethoxazole

57

Prevention of graft versus host disease

Mtx

58

Secondary prophylaxis: Cryptococcus neoformans

fluconazole

59

active against HBV and HIV

Lamivudine (nucleoside analog of cytosine), Emtricitabine (fluorinated analog of lamivudine), Tenofovir (nucleotide analog of adenosine)

60

Prevention and treatment of VTE: In patients with atrial fibrillation and a presumed cardiac source of embolism, the antithrombotic agent of first choice for primary and secondary prevention of ischemic stroke

warfarin