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Clinical Use Flashcards

(60 cards)

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1
Q

Intraarticular for chronic pain resulting from permanent joint changes

A

Dexamethasone

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2
Q

parenteral iron

A

(a) Patients in whom GI absorption is prevented by disease (b) Patient who cannot tolerate orally administered iron (c) Hemodialysis patients (Sodium ferric gluconate and iron sucrose)

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3
Q

Effective against P. falciparum

A

Halofantrine

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4
Q

immunosuppressant for transplantation

A

tacrolimus

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5
Q

Gametocidal

A

Primaquine

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6
Q

cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP)

A

non-Hodgkin lymphoma

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7
Q

Primary and secondary prevention of thromboembolism in patients with nonvalvular atrial fibrillation

A

Dabigatran

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8
Q

used in pregnant patients with severe allergic reactions to heparin (e.g., HIT).

A

Fondaparinux and parenteral direct thrombin inhibitors

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9
Q

(a) Patients in whom GI absorption is prevented by disease (b) Patient who cannot tolerate orally administered iron (c) Hemodialysis patients (Sodium ferric gluconate and iron sucrose)

A

parenteral iron

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10
Q

Treatment and chemoprophylaxis of P. falciparum infections

A

“Atovaquone-proguanil aka Malarone”

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11
Q

standard prophylactic drug in SE Asia (in combination with mefloquine)

A

Doxycycline

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12
Q

fludarabine

A

CLL

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13
Q

circumvents the action of inhibitors of dihydrofolate reductase and potentiates the cytotoxic effects of 5- fluorouracil

A

Leucovorin (folinic acid)

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14
Q

DIC in patients where bleeding predominates

A

Fresh frozen plasma

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15
Q

eluting stents - Approved for coronary artery disease

A

sirolimus

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16
Q

Pneumocystis jiroveci: Prophylaxis for first-episode infection and therapy for pneumonia

A

Trimethoprim/sulfamethoxazole

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17
Q

von Willebrand disease (types 1 or 2A)

A

DDAVP (desmopressin)

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18
Q

Radical cure and terminal prophylaxis of infections with P. vivax and P. ovale; alternative chemoprophylaxis for all species

A

Primaquine

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19
Q

Infants usually receive an intramuscular injection at birth for VKDB prophylaxis

A

Phytonadione

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20
Q

Treatment (with quinine) of infections with P. falciparum

A

Doxycycline

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21
Q

Megaloblastic anemia

A

IM B12 and folic acid

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22
Q

Thromboprophylaxis in patients undergoing hip or knee replacement surgery

A

rivaroxaban

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23
Q

therapy of choice for many systemic fungal infections

A

Polyenes: Amphotericin B; followed by outpatient treatment with azoles

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24
Q

blood schizontocide

A

Artemisinin Chloroquine Mefloquine Doxycycline Quinine and Quinidine Sulfadoxine-pyrimethamine

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25
Used only in combination with amphotericin B
flucytosine
26
autoimmune disease, e.g., autoimmune hemolytic anemia
MPA or MMF; (Mycophenolic Acid and Mycophenolate Mofetil)
27
Daclizumab and Basiliximab
Induction therapy for renal transplantation
28
Adequate for minor bleeding episodes in patients with mild hemophilia A
DDAVP (desmopressin)
29
used for prevention and acute treatment of VTE
heparin, LMWH, fondaparinux
30
Treatment and secondary prevention of VTE (DVT or pulmonary embolism)
rivaroxaban
31
patients with pernicious anemia or ileal disease
Cyanocobalamin (parenteral)
32
Tretinoin
APL
33
Drug of choice for treatment of P. falciparum-sensitive malaria & chemoprophylaxis of malaria
Chloroquine
34
DIC in patients where thrombosis predominates
Heparin
35
Immunosuppressants in patients with inflammatory bowel disease
azathioprine
36
used in patients with HIT to prevent further thromboembolic complications
Lepirudin and argatroban
37
Chemoprophylaxis and Treatment of infections with chloroquine‐resistant P. falciparum
Mefloquine
38
von Willebrand disease (types 2B, 2M, and 3)
Plasma-derived vWF-containing products
39
prophylactic administration when there is increased utilization such as in pregnancy and lactation
folate
40
Iron poisoning if plasma concentration of iron \> 3.5 mg/L
Deferoxamine
41
Primary prophylaxis (regular replacement therapy) started at a young age before onset of joint bleeding in hemophilia A/B
Factor VIII/IX replacement Plasma-derived products; Recombinant factor VIII/IX
42
In patients with pernicious anemia high doses are used since it is absorbed via passive diffusion
Cyanocobalamin (oral)
43
High doses can control bleeding in acute bleeding episodes
Factor VIII/IX replacement Plasma-derived products; Recombinant factor VIII/IX
44
ABVD - doxorubicin [Adriamycin], bleomycin, vinblastine, and dacarbazine
Hodgkin lymphoma
45
First line therapies for P. falciparum malaria, especially cerebral malaria
Quinine and Quinidine
46
Treatment of acute bleeding episodes in patients with low inhibitor titer
Aminocaproic acid; Tranexamic acid
47
Therapy for meningitis caused by Cryptococcus neoformans
Amphotericin B + flucytosine followed by fluconazole
48
Active against hepatic-stage schizonts"
Primaquine "Atovaquone-proguanil aka Malarone"
49
Vitamin K deficiency
Phytonadione
50
imatinib
CML
51
Treatment of acute bleeding episodes in patients with high inhibitor titer
Prothrombin complex concentrate (PCC) and activated PCC (aPCC) OR Recombinant factor VIIa
52
Therapy for encephalitis cause by Toxoplasma gondii
Pyrimethamine/sulfadiazine
53
Treatment of infections with some chloroquine‐resistant P. falciparum; could be combined with artesunate; preventive therapy in endemic areas
Sulfadoxine-pyrimethamine
54
preferred for prevention and treatment of VTE in pregnancy
Low-molecular weight heparins (e.g., enoxaparin)
55
Available as a fixed dose combination with Artemether – 1st line therapy for uncomplicated malaria in most of Africa
Lumefantrine
56
Prophylaxis for first episode Toxoplasma gondii
Trimethoprim/sulfamethoxazole
57
Prevention of graft versus host disease
Mtx
58
Secondary prophylaxis: Cryptococcus neoformans
fluconazole
59
active against HBV and HIV
Lamivudine (nucleoside analog of cytosine), Emtricitabine (fluorinated analog of lamivudine), Tenofovir (nucleotide analog of adenosine)
60
Prevention and treatment of VTE: In patients with atrial fibrillation and a presumed cardiac source of embolism, the antithrombotic agent of first choice for primary and secondary prevention of ischemic stroke
warfarin

Heme Pharm (13 decks)

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