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Heme Pharm > Clinical Use > Flashcards

Clinical Use Flashcards

1
Q

Intraarticular for chronic pain resulting from permanent joint changes

A

Dexamethasone

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2
Q

parenteral iron

A

(a) Patients in whom GI absorption is prevented by disease (b) Patient who cannot tolerate orally administered iron (c) Hemodialysis patients (Sodium ferric gluconate and iron sucrose)

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3
Q

Effective against P. falciparum

A

Halofantrine

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4
Q

immunosuppressant for transplantation

A

tacrolimus

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5
Q

Gametocidal

A

Primaquine

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6
Q

cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP)

A

non-Hodgkin lymphoma

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7
Q

Primary and secondary prevention of thromboembolism in patients with nonvalvular atrial fibrillation

A

Dabigatran

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8
Q

used in pregnant patients with severe allergic reactions to heparin (e.g., HIT).

A

Fondaparinux and parenteral direct thrombin inhibitors

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9
Q

(a) Patients in whom GI absorption is prevented by disease (b) Patient who cannot tolerate orally administered iron (c) Hemodialysis patients (Sodium ferric gluconate and iron sucrose)

A

parenteral iron

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10
Q

Treatment and chemoprophylaxis of P. falciparum infections

A

“Atovaquone-proguanil aka Malarone”

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11
Q

standard prophylactic drug in SE Asia (in combination with mefloquine)

A

Doxycycline

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12
Q

fludarabine

A

CLL

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13
Q

circumvents the action of inhibitors of dihydrofolate reductase and potentiates the cytotoxic effects of 5- fluorouracil

A

Leucovorin (folinic acid)

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14
Q

DIC in patients where bleeding predominates

A

Fresh frozen plasma

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15
Q

eluting stents - Approved for coronary artery disease

A

sirolimus

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16
Q

Pneumocystis jiroveci: Prophylaxis for first-episode infection and therapy for pneumonia

A

Trimethoprim/sulfamethoxazole

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17
Q

von Willebrand disease (types 1 or 2A)

A

DDAVP (desmopressin)

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18
Q

Radical cure and terminal prophylaxis of infections with P. vivax and P. ovale; alternative chemoprophylaxis for all species

A

Primaquine

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19
Q

Infants usually receive an intramuscular injection at birth for VKDB prophylaxis

A

Phytonadione

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20
Q

Treatment (with quinine) of infections with P. falciparum

A

Doxycycline

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21
Q

Megaloblastic anemia

A

IM B12 and folic acid

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22
Q

Thromboprophylaxis in patients undergoing hip or knee replacement surgery

A

rivaroxaban

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23
Q

therapy of choice for many systemic fungal infections

A

Polyenes: Amphotericin B; followed by outpatient treatment with azoles

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24
Q

blood schizontocide

A

Artemisinin Chloroquine Mefloquine Doxycycline Quinine and Quinidine Sulfadoxine-pyrimethamine

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25
Q

Used only in combination with amphotericin B

A

flucytosine

26
Q

autoimmune disease, e.g., autoimmune hemolytic anemia

A

MPA or MMF; (Mycophenolic Acid and Mycophenolate Mofetil)

27
Q

Daclizumab and Basiliximab

A

Induction therapy for renal transplantation

28
Q

Adequate for minor bleeding episodes in patients with mild hemophilia A

A

DDAVP (desmopressin)

29
Q

used for prevention and acute treatment of VTE

A

heparin, LMWH, fondaparinux

30
Q

Treatment and secondary prevention of VTE (DVT or pulmonary embolism)

A

rivaroxaban

31
Q

patients with pernicious anemia or ileal disease

A

Cyanocobalamin (parenteral)

32
Q

Tretinoin

A

APL

33
Q

Drug of choice for treatment of P. falciparum-sensitive malaria & chemoprophylaxis of malaria

A

Chloroquine

34
Q

DIC in patients where thrombosis predominates

A

Heparin

35
Q

Immunosuppressants in patients with inflammatory bowel disease

A

azathioprine

36
Q

used in patients with HIT to prevent further thromboembolic complications

A

Lepirudin and argatroban

37
Q

Chemoprophylaxis and Treatment of infections with chloroquine‐resistant P. falciparum

A

Mefloquine

38
Q

von Willebrand disease (types 2B, 2M, and 3)

A

Plasma-derived vWF-containing products

39
Q

prophylactic administration when there is increased utilization such as in pregnancy and lactation

A

folate

40
Q

Iron poisoning if plasma concentration of iron > 3.5 mg/L

A

Deferoxamine

41
Q

Primary prophylaxis (regular replacement therapy) started at a young age before onset of joint bleeding in hemophilia A/B

A

Factor VIII/IX replacement Plasma-derived products; Recombinant factor VIII/IX

42
Q

In patients with pernicious anemia high doses are used since it is absorbed via passive diffusion

A

Cyanocobalamin (oral)

43
Q

High doses can control bleeding in acute bleeding episodes

A

Factor VIII/IX replacement Plasma-derived products; Recombinant factor VIII/IX

44
Q

ABVD - doxorubicin [Adriamycin], bleomycin, vinblastine, and dacarbazine

A

Hodgkin lymphoma

45
Q

First line therapies for P. falciparum malaria, especially cerebral malaria

A

Quinine and Quinidine

46
Q

Treatment of acute bleeding episodes in patients with low inhibitor titer

A

Aminocaproic acid; Tranexamic acid

47
Q

Therapy for meningitis caused by Cryptococcus neoformans

A

Amphotericin B + flucytosine followed by fluconazole

48
Q

Active against hepatic-stage schizonts”

A

Primaquine “Atovaquone-proguanil aka Malarone”

49
Q

Vitamin K deficiency

A

Phytonadione

50
Q

imatinib

A

CML

51
Q

Treatment of acute bleeding episodes in patients with high inhibitor titer

A

Prothrombin complex concentrate (PCC) and activated PCC (aPCC) OR Recombinant factor VIIa

52
Q

Therapy for encephalitis cause by Toxoplasma gondii

A

Pyrimethamine/sulfadiazine

53
Q

Treatment of infections with some chloroquine‐resistant P. falciparum; could be combined with artesunate; preventive therapy in endemic areas

A

Sulfadoxine-pyrimethamine

54
Q

preferred for prevention and treatment of VTE in pregnancy

A

Low-molecular weight heparins (e.g., enoxaparin)

55
Q

Available as a fixed dose combination with Artemether – 1st line therapy for uncomplicated malaria in most of Africa

A

Lumefantrine

56
Q

Prophylaxis for first episode Toxoplasma gondii

A

Trimethoprim/sulfamethoxazole

57
Q

Prevention of graft versus host disease

A

Mtx

58
Q

Secondary prophylaxis: Cryptococcus neoformans

A

fluconazole

59
Q

active against HBV and HIV

A

Lamivudine (nucleoside analog of cytosine), Emtricitabine (fluorinated analog of lamivudine), Tenofovir (nucleotide analog of adenosine)

60
Q

Prevention and treatment of VTE: In patients with atrial fibrillation and a presumed cardiac source of embolism, the antithrombotic agent of first choice for primary and secondary prevention of ischemic stroke

A

warfarin

Heme Pharm (13 decks)

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