Flashcards in CO2 + O2 (Colombo) Week 3 Deck (18):
Give the defintion of Partial Pressure
The pressure of an INDIVIDUAL gas in a fiven volume at a constant pressure
What is the difference between alveolar air and atmospheric air?
Alveolar air contains CO2 and H20, they make up a small portion but they end up diluting the O2 and N2 from the atmospheric air
How can the distance of diffusion pathologically increased?
By damage to the alveoli, pulmonary diseases will cause this. Making it harder for O2 to diffuse into the blood.
Define Tidal Volume
Normal volume of air dispalced between inhalation and exhalation.
What is Functional residual capacity
part of tidal volume, allows for there to not be any sudden changes or irregularites keeping the blood gas levels constant.
What are the 2 factors that control the amount of o2 in the alveoli
2. Rate of absorption from blood.
What happens when there is a high metabolic demand to o2 and co2
o2 - decreases amount in blood
co2 - increases amount in blood.
What is the Ventilation/Perfusion Ratio?
The relationship between alveolar ventilation &a alveolar perfusion.
(doesnt matter how much air you can get into your lungs if the o2 cant perfuse into bloodstream)
VA = Ventilation
Q = Blood flow
What is Shunted blood and what is the Physiologic Shunt
Shunted Blood is the non-perfused blood
Physiologic shunt is the amount of shunted blood that passes throught the circulatorysystem/minute
What 2 factors effect the transport of blood gases?
1. Rate of diffusion
2. movement of blood
What is the partial pressure of O2 when leaving alveoli?/Returning?
40 mm Hg
What makes it so O2 can be soluble in blood
RBC's have Hemaglobin hich have an affinity for O2.
However the affinity varies depending on concenctration of O2 in blood
Describe the Hemoglobin O2 affinity
High PP O2 favor Hb binding
Low = favor O2 disassociation
Define Cooperative Binding
The more O2 HB has the easier it is for another O2 molecule to bind.
How many binding sites does Hb have?
4 - each site has 2 O2 molecules resulting in a total of 8 O2 molecules if full.
How much more soluble is Co2 than O2
20x more than O2