Coagulation and RBC disords

Question 1

Describe anemia

Answer 1

• decrease oxygen capacity of RBC

Question 2

forms of anemia

Answer 2

1. decrease RBC numbers
2. Decrease hemoglobin numbers

Question 3

s+S of anemia

Answer 3

-fatigue
- feeling cold
- paleness
- dizziness

Question 4

Types of anemia

Answer 4

1. iron deficiency anemia
2. macrocytic anemia

Question 5

what is iron deficiency

Answer 5

• decreased iron = decrease hemoglobin synthesis = RBC become microcytic and hypochromic

Question 6

why iron deficiency occurs

Answer 6

• decrease iron intake
• decrease iron absorption
• decrease HCL
• increase demand for iron

Question 7

what is macrocytic anemia

Answer 7

-RBC large but immature + decrease RBC numbers

Question 8

why macrocytic occurs

Answer 8

• decrease folic acid
• increase loss of folic acid
• increase demand

Question 9

pathophysiology of disseminated intravascular coagulation

Answer 9

• wide spread of blood clots through vascular system

Question 10

when does disseminated intravascular coagulation happen

Answer 10

Severe endothelial damage (include obstetric complications, physical trauma, malignancy, sepsis, hemorrhage)

Triggers increase release of tissue factor (released from damaged tissue to stimulate clotting) = increase pro-coagulation/decrease anti-coagulations = excessive coagulation response = clotting occurs throughout vasculature =

One of the following

tissue ischemia = keep stimulating excess coagulation response = causes damage

increase plasmin = increase fibrinolysis = hemorrhage = hypovolemic shock

Coagulation factors all used up = hemorrhage = hypovolemic shock