Cognition and Association Cortices Flashcards Preview

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Flashcards in Cognition and Association Cortices Deck (51)
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1

What is cognition?


it's basically our inner life

perception, attention, memory, language, emotion, planning and consciousness

2

What is the default network and when is it active?


The default network is the combination of brain regions that are more active during "rest" as opposed to during tasks

it's involved in daydreaming or mind wandering, autobiographical memories, envisioning the future and moral decisions

It contrasts with the "task positive network"

3

What is the status of the default network in schizophrenia, depression, and autism?


schizophrenia = doesn't turn off properly when the task network is on

depression = default network is way overactive (rumination)

autism = default network is hypoactive

4

What are the two basic types of association cortex?


unimodal (dealing with only one sensory modality)

multimodal (incorporates multiple modalities)

5


WHat are the 4 primary sensory areas?


1. motor

2. auditory

3. somatosensoty

4. visual

6


What's technically the motor association cortex?


the premotor area

7


What is the general pathway of sensory informaiton flow through the association cortices?


1. primary sensory cortex

2. unimodal association cortex

3. multimodal association cortex

4. premotor cortex

5. motor cortex (to respond)

8


How many layers of cortex are there?


6

9


How does the primary visual cortex (and other sensory cortices) differ cytoarchtecturally from the primary motor cortex?


primary visual cortex - thinner, but layer 4 is much thicker (this is a granular layer - receives info from the thalamus)

primary motor cortex - thicker, but layer 4 is thin and layer 5 is especially thicker (this is the pyramidal layer for output)

10


What cell type is located throughout the layers of the cortex? What cell type is really only in layer 4?


pyrmidal cells are everywhere

stellate cells are in layer 4

11


The primary sensory cortices receive input from what? Into what layer?


from the thalamus into layer 4

12


What 4 areas of the thalamus provide input to the primary sensory cortices?


lateral geniculate - visual info

medial geniculate - auditory info

ventral posterior medial - somatosensory

ventral posterior lateral - somatosensory

13


Where do the association cortices get input from? To what layer?


From the MULTIMODAL thalamic nuclei, to layer 4

14


What are the 4 multimodal thalamic nuclei?


1. pulvinar - visual

2. medial dorsal - supeerior colliculus, olfaction, amygdala, ventral pallidum

2. lateral posterior - association cortex, anterior cingulate, retina

4. anterior - hypothalamus, hippocampus, cingulate

15

What layers receive input from other areas of the cortex (not thalamus)?

Does this differ between the primary and association cortices?


1, 2, 3, and 5

it differs in that the association cortices just get a lot more information than the primary cortices

16

From what two layers do the sensory and assocition cortices send output to other cortical areas?


2 and 2

17


Which two layers project out of the primary and association cortices to the thalamus? Which one also provides output to the other subcortical areas like the basal ganlgia, mdibrain, brainstem and spinal cord?


5 and 6

5 is the one that goes to the thalamus and other subcortial areas

18


Therefore, what layer of the cortex gives you motor function?


layer 5

19


What layer receives MODULATORY input from the thalamus?


layer 1

20


Wall cortical layers receive modulatory input from the brain stem with what NTs?


5HT, DA, NE and ACh

21


How does the function of the parietal association cortex differ based on what hemisphere its in?


nondominant hemisphere = attention, visupspatial localization (where's waldo", spatial relationships

dominant hemisphere = skilled movements, right-left orientation

22


Specifically, where is the seat of attention based?


in the nondominant posterior parietal cortex (also called the inferolateral parietal cortex)

23


What is the physiological basis for selective attention found in the posterior parietal?


recordsing in monkey parietal association cortex are only active when they attend to a certain target

this allows selective attention - blocking out stimulus we don't need to pay attention to

24


What mental disorder has a marked deficiency in selective attention?


schizophrenia

25


What neuropsych test is used to test selective attention?


stroop test

26


Damage to the nondominant posterior parietal cortex will result in what?


spatial neglect (left-sided neglect)

27

Damage in the dominant posteiorr parietal cortex will result in what?


motor apraxias

28


What are some characteristics of spatial neglect?


it's a failure to acknowledge half of the world.

note that it's not an issue of the sensory system or of perception - it's an attention problem

applies to emviornment, patient's own body, and even memory and visualizations

29


What is the incidence of spatial neglect in right-hemisphere strokes?


nearly 50%!

30


Damage to what areas of the brain will result in motor apraxias?


anywhere in the motor cortex obviously, but also in the interparietal sulcus