Common bacterial pathogens 3

Question 1

neisseria gonorrhoeae typically infects what two areas

Answer 1

mucous memranes (vag) and conjunctivitis (blindness in infants)

Question 2

whats a protective resopnse to gonorrhoaeae

Answer 2

pills BUT antigenic variation so hard

Question 3

prolonged gonorrhoaeae infections lead to what

Answer 3

scarring and fibrosis

Question 4

gonorhoaeae in men

Answer 4

asymptomatic to urethritis

Question 5

gonorrhoeae in females

Answer 5

infection of crevice and urethra and can climb up uterine tubes to cause fibrosis and infertility and is more often asymptomatic than males

Question 6

pilus in gonorrhoaeae is important for

Answer 6

adherence and interfering with neutrophil killing

Question 7

neisseria gonorrhoaeae is almost ALWAYS resistant to what and is usually resistant to 2 other things

Answer 7

always- penicillin, cephalosporins and fluroquinolone

Question 8

prototypical endogeneous anaerobic pathogen

Answer 8

bacteroides fragilis

Question 9

what bacteria is associated with over 80% of intra abdominal infections

Answer 9

bacteroides fragilis

Question 10

bactericiodes common to oral cavity are associated with

Answer 10

anaerobic infections above diaphragm

Question 11

how does bactericides fraigilis feel about oxygen

Answer 11

aerotolerant

Question 12

what causes rocky mountain spotted fever

Answer 12

rickettsia

Question 13

how does rickettsia get ATP

Answer 13

can’t make its own- requires on infected host cell

Question 14

chalmidia trachnomatisis is what class of bacteria

Answer 14

obligate intracellular

Question 15

2 diseases caused by chalmydia

Answer 15

trachoma and genital infections

Question 16

trachnoma is what and where is it a problem

Answer 16

conjuctiva infection that causes scarring and blindness and is endemic in africa and asia

Question 17

chlamydia is often found in co infections with what

Answer 17

n. gonorrhoeae

Question 18

men with chlamydia how do they present

Answer 18

non gonococcal urethritis

Question 19

3 things women get from chlamydia

Answer 19

PID, urethritis, cervicitis

Question 20

2 diseases that chlamydia gives neonate

Answer 20

conjunctivitis and pneumonia

Question 21

most common causes of pneumonia ages 5-20

Answer 21

mycoplsama pneumoniae

Question 22

how severe is mycoplasma pneumonia

Answer 22

mild

Question 23

mycoplasma adheres to ____ and growth is ____

Answer 23

respiratory epithelial cells and extracellular

Question 24

how does mycoplasma pneumonia get transmited

Answer 24

infected respiratory secretions

Question 25

mycoplsama pneumonia sypmtoms

Answer 25

fever, headache, sore throat, NON PRODUCTIVE COUGH, chest/body aches, fatigue

Question 26

resolution of mycoplasma pneumonia is what temp

Answer 26

1-4 weeks

Question 27

how do you treat mycoplasma pneumonia (or what NOT to use)

Answer 27

they DONT have cell wall aka don't use penicillins

Question 28

diagnosing mycoplasma pneumonia

Answer 28

culture is really hard (has to be in a cell free medium?) so use serum test or pcr

Question 29

what bacteria doenst stain with gram stain

Answer 29

mycoplasma pneumonia because doesn't have cell wall

Question 30

2 virulence factors of mycoplasma pneumonia

Answer 30

hydrogen peroxide and superoxide radicals

Question 31

toxic LPS moiety

Answer 31

Lipid A

Question 32

smaller doses of LPS lead to what via whyat cytokines

Answer 32

fever and shock IL1 and TNF

Question 33

larger doses of LPs lead to what 3 things

Answer 33

hypotension, hemorrhage, intracascular coagulatin

Question 34

3 ways LPS gets released from cell wall fragments

Answer 34

antibiotic treatment, injecting contaminated materials, bacteremia

Question 35

gram - membrane is a permeability barrier that protects the cell from some antibiotics like

Answer 35

erythromycin

Question 36

superantigens do what

Answer 36

nonspecific T cell activation with MASSIVE CYTOKINE release

Question 37

Big 3 to think about for empiric use of antibiotics

Answer 37

MRSA, pseudomonas, anaerobes

Question 38

3 organisms most commonly responsible for bacterial endocarditis

Answer 38

S. aureus, strep viridans, coagulase negative staphylococci (like S epidermidis)

Question 39

when you think endospores think of this pathogen

Answer 39

clostridiuj

Question 40

infectious anaerobes are usually from where

Answer 40

endogenous

Question 41

typical anaerobic lesion i swhat

Answer 41

abscess

Question 42

hallmark of anaerobic lesion is

Answer 42

mixed infection

Question 43

rickettsia and chlamydia are what class

Answer 43

obligate intracellular bacteria

Question 44

2 genera of bacteria that lack cell walls and have sterols in plasma membrane

Answer 44

mycoplasma and ureaplasma