concept 6b part 2 Flashcards
(50 cards)
consciousness-altering drugs
4 different groups: depressants, stimulants, opiates, and hallucinogens
marijuana has depressant, stimulant, and hallucinogenic effects and considered separately
depressants
reduce nervous system activity
resulting in sense of relaxation and reduced anxiety
alcohol is most common type, but also include barbiturates and benzodiazepines
alcohol
has several effects on the brain
increases activity of the GABA receptor, a chloride channel that causes hyper polarization of the membrane
causes brain inhibition, resulting in diminished arousal
increases dopamine levels, causing sense of euphoria
logical reasoning and motor skills are affect and fatigue may result
often measured using blood alcohol levels
alcohol myopia
main effects of alcohol on logical reasoning
the inability to recognize consequences of actions
this creates a short-sighted view of the world
alcoholism
rates are higher for those in lower socioeconomic status, but low-SES alloys enter recovery sooner and at higher rates
tends to run in families
long-term consequences include cirrhosis and liver failure, pancreatic damage, gastric or duodenal ulcers, gastrointestinal cancer, and brain disorders including Wernicke-Korsakoff syndrome
Wernicke-Korsakoff Syndrome
caused by a deficiency of thiamine (vitamin B1)
characterized by sever memory impairment with changes in mental status and loss of motor skills
barbiturates
historically used as anxiety-reducing (anxiolytic) and sleep medications
have been replaced by benzodiazepines
include amobarbital and phenobarbital
benzodiazepines
replace barbiturates
are less prone to overdoes
include alprazolam, lorazepam, diazepam, and clonazepam
increase GABA activity, causing sense of relaxation
highly addictive
stimulants
cause an increase in arousal in the nervous system
each drug increases the frequency of action potentials
amphetamines, cocaine, ecstasy
amphetamines
cause increased arousal by increasing release of dopamine, norepinephrine, and serotonin at the synapse and decreasing their reuptake
increases arousal, causes reduction in appetite and decreased need for sleep
increase heart rate and blood pressure
psychological effects include euphoria, hyper vigilance (being “on edge”), anxiety, delusions of grandeur, and paranoid
cocaine
originates from the coca plant, grown in high-altitude regions of South America
decreases repute of dopamine, norepinephrine, and serotonin
effects and withdrawal are similar to amphetamines
have anesthetic and vasoconstrictive properties
crack
form of cocaine that can be smoked
with quick and potent effects
highly addictive
ecstasy
acts as a hallucinogen combined with an amphetamine
mechanism and effects similar to amphetamines
causes increased heart rate, increased blood pressure, blurry vision, sweating, nausea, and hyperthermia
causes feelings of euphoria, increased alertness, and overwhelming sense of well-being and connectedness
opium
derived from the poppy plant
numerous drugs derived from this that are used recreationally and therapeutically
opiates
naturally occurring forms of opium
morphine and codeine
bind to opioid receptors in the peripheral and central nervous system
causing a decreased reaction to pain and a sense of euphoria
overdoes can cause death by respiratory suppression, brain stops sending signals to breathe
opioids
semisynthetic derivatives of opium
oxycodone, hydrocodone, and heroin
bind to opioid receptors in the peripheral and central nervous system
causing a decreased reaction to pain and a sense of euphoria
overdoes can cause death by respiratory suppression, brain stops sending signals to breathe
heroin
originally created as a substitute for morphine
once injected body rapidly metabolizes heroin to morphine
usually smoked or injected
was the most widely abused opioid, but now it is prescription opioids like oxycodone and hydrocodone
hallucinogens
include drugs such as lysergic acid diethyl amide (LSD), peyote, mescaline, ketamine, and psilocybin-containing mushrooms
exact mechanism is unknown, but thought to be complex interaction b/w various neurotransmitters especially serotonin
cause distortions of reality and fantasy, enhancement of sensory experiences, and introspection
increased heart rate and blood pressure, dilation of pupils, sweating, and increased body temperature
marijuana
leaves and flowers of 2 plane species: Cannabis sativa and Cannabis indica
active chemical is tetrahydrocannabinol (THC)
exerts effects by acting at cannabinoid receptors, glycine receptors, and opioid receptors
has depressant, stimulant, and hallucinogenic effects
THC increases GABA activity, causing neural inhibition, and dopamine activity, causing pleasure
cause eye redness, dry mouth, fatigue, impairment of short term memory, increased heart rate, increased appetite, and lowered blood pressure
drug addiction
highly related to the mesolimbic reward pathway, 1 of 4 dopaminergic pathways in brain
addiction pathway is activated by all substances that produce psychological dependence
mesolimbic reward pathway
highly related to drug addiction, is the addiction pathway
includes the nucleus accumbens, the ventral tegmental area, and the connections b/w them called the medial forebrain bundle
normally involved in motivation and emotional response
activation accounts for the positive reinforcement of substance abuse
gambling and falling in love also activate this pathway
attention
concentrating on one aspect of the sensory environment or sensorium
understanding of how attention works and the mechanism by which we can shift our attention from one set of stimuli to another is unclear
selective attention
focusing on one part of the sensorium while ignoring other stimuli
acts as a filter b/w sensory stimuli and our processing systems
probably a filter that allows us to focus on one thing while allowing other stimuli to be processed in the background
cocktail party phenomenon
cocktail party phenomenon
at a party and talking to a friend
your ears perk up when you hear your name spoken across the room
even though you were engaged in conversation you were able to perceive your name being mentioned
evidence of different interpretation of selective attention