Conj / Cornea / Iris

Question 1

Which fungi causes isolated conjunctivitis seen mostly in India and Southeast Asia?

Answer 1

Rhinosporidium seeberi

Question 2

Recurrent pterygia look like what histopathologically?

Answer 2

Lack elastotic degeneration and are more accurately classified as an exuberant fibrous tissue response.

Question 3

What distribution does amyloid have in the conj?

Answer 3

Perivascular distribution

Question 4

Amyloid deposit affecting the skin of the eyelid reflects what?

Answer 4

Systemic condition

Question 5

Amyloid deposits affecting the palpebral conj reflects what?

Answer 5

Localized pathology

Question 6

HPV 6 and 16 affect what age group for papillomas?

Answer 6

6 - kids

16 - adults

Question 7

What is the normal changes of nevi?

Answer 7

1. Initially junctional phase

2. Soley substantia propria.

Question 8

Approx what % of conj melanoma arise from PAM with atypic?

Answer 8

2/3

Question 9

What are 4 unfavorable prognostic factors for conj melanoma?

Answer 9

1. Nonepibulbar location
2. histopathological identification of pagetoid or full-thickness intraepithelial spread
3. involvment of the eyelid skin margin
4. Tumors greater than 1.8mm carry greater risk for dissemination and death

Question 10

Where do metatistis first develop for conj melanoma?

Answer 10

1. Parotid LN

2. Submandibular LN

Question 11

What type of keratitis is seen as a complication of trauma or of corticosteroid use?

Answer 11

Fungal (able to penetrate into the AC)

Question 12

What are the 3 special stains used to mycotic keratitis?

Answer 12

1. Grocott-Gomori methenamine-silver nitrate
2. PAS
3. Giesma

Question 13

Non-nutrient blood agar layered with E coli is used to grow what?

Answer 13

Acanthamoeba

Question 14

Histopatholically Salzmann nodular degeneation is what?

Answer 14

Gray/blue elevated lesions made up of hyaline material and ABSENCE OF BOWMAN’S LAYER.

Question 15

Pannus is growth of tissue where?

Answer 15

Between the epithelium and Bowman’s layer

Question 16

What are the earliest histological changes in KCN?

Answer 16

Focal discontinuities of the epithelial BM and Bowman’s layer.

Question 17

Spontaneous rupture in which membrane leads to acute stromal edema or hydrous?

Answer 17

DESCEMET’S

Question 18

What are causes of spontaneous breaks in Descement’s?

Answer 18

1. Terrien Marginal degeneration

2. Pellucid Marginal degeneration

Question 19

Whorl like keratopathy occurs where?

Answer 19

BASAL layer of the epithelium

Question 20

What stain is used to bring out corneal iron lines?

Answer 20

Prussian blue or Perls test.

Question 21

Abnl proliferation of WHAT is a constant feature of all forms of ICE syndrome?

Answer 21

ENDOTHELIUM with descements

Question 22

Exfoliation syndrome has been a/w what?

Answer 22

1. HTN
2. CVA
3. MI

Question 23

What % of patients having greater than 180 degrees of angle recession develop GL?

Answer 23

5-10%

Question 24

Ciliary nerves may have pigmented melanocytes along their nerve sheaths that appear as pigmentation on the epibulbar surface =

Answer 24

Axenfeld nerve loop (through a transmural emissarial channel)

Question 25

Sclera stroma is made up of what type of collagen?

Answer 25

Type 1

Question 26

Where are episcleral osseous choristomas ususally found?

Answer 26

ST quad

Question 27

Name the 3 layers of zonal granuloma?

Answer 27

1. Inner - multinuclearted giant cells and PMNs adjacent to the degnerating lens material 2. Lymphocytes and histiocytes 3. fibrous connective tissue and collagen

Question 28

After what type of cataract surgery does Elschnig pearls form?

Answer 28

Extracapsular - remaining epithelial cells proliferate and cover the inner surface of the posterior capsule.

Question 29

What is sequestration of proliferating lens fibers in the equatorial region, often as a result of incomplete cortical removal, creates a doughnut shaped configuration called?

Answer 29

Soemmerring ring

Question 30

What are the 2 categories of cortical lens degeneration ?

Answer 30

1. generalized discolorations with loss of transparency | 2. focal opacifications

Question 31

What is the clinical evaluation of a suspicious iris nevi?

Answer 31

1. Slit lamp photography | 2. UBM!!

Question 32

How do you differentiate primary vs recurrent ptyergium?

Answer 32

Lack of elastoid degeneration in recurrent.

Question 33

Verhoeff-van Geisma stains what?

Answer 33

Elastotic material - pingeculum

Question 34

How do u fix eyelid laceration?

Answer 34

the eyelid margin closure should result in a MODERATE EVERSION of the well-approximated wound edges.

Question 35

What is the inheritance of megalocornea?

Answer 35

X linked recessive

Question 36

In what disease is it classically seen where Bowman's membrane is destroyed by inflammatory pannus?

Answer 36

Trachoma

Question 37

In Terrian's degeneration, what layers of the cornea are lost?

Answer 37

Bowmans and superficial stroma (epithelium intact)

Question 38

What do u see in KCN?

Answer 38

Dehisence in Bowman's membrane with compensatory epithelial hyperplasia

Question 39

Mutation in GELSOLIN is seen in what dz?

Answer 39

Lattice type 2 (Meretoja)

Question 40

In Terrian's degeneration, what layers of the cornea are lost?

Answer 40

Bowmans and superficial stroma (epithelium intact)

Question 41

What do u see in KCN?

Answer 41

Dehisence in Bowman's membrane with compensatory epithelial hyperplasia

Question 42

Mutation in GELSOLIN is seen in what dz?

Answer 42

Lattice type 2 (Meretoja)

Question 43

What do you see in a Cortical cataract?

Answer 43

Morgagian globules - round, eosinophilc, NO NUCELI

Question 44

Degenerative pannus presents how?

Answer 44

Fibrous tissue between base of epithelium and INTACT BOWMANS membrane (seen with chronic corneal edema) (Inflammatory pannus DESTROYs Bowmans)

Question 45

What are the 3 layers of ZONAL inflm?

Answer 45

1. PMNs around lens material 2. Epitheloid cells (granulomatous) 3. Lymphocytes, eosinophils, granulation tissue