Wound Repair Flashcards
What are the series of reactions that follow a wound?
- Acute inflm
- Regeneration
- Contraction
What stops further migration of epithelial cells during a cornea abrasion?
Contact inhibition
How long does it take a corneal abrasion to fully heal?
4-6 weeks
How does the corneal stroma heal?
Fibrosis NOT fibrovascular proliferation
Following a central corneal wound, how do PMNs get the the wound?
via the TEARS (PMNs carry lysozyme)
How do wounds to the limbus heal?
Swelling in the cornea and shrinking of the sclera.
What are retinal scars produce by?
GLIA not fibroblast
After injury to the skin, when do myofibroblasts arrive to the wound and start contraction?
Day 3… so early contraction doesnt happen.
In cyclodialysis why does IOP go down?
- Free access to the suprachorodial space
2. blood supply to the ciliary body is diminished
Which muscles of the ciliary body atrophy after trauma?
The oblique and circular muscles - making it a fusiform shape from triangular
What are the 3 attachment points of the uveal tract to the sclera?
- Scleral spur
- Internal ostia of the vortex veins
- peripapillary tissue
What is chorioretinal rupture and necrosis known as?
Sclopetaria
In phthisis bulbi where does the sclera become massively thickened?
Posteriorly
von Kossa stains for what?
Band keratopathy - calcium phosphate salts - black
Verhoeff-van Gieson stain for what?
Temporal artery elastic layer - elastic fibers:black
