Cushings Flashcards
(8 cards)
1
Q
Define conditon
A
Resulting from excess cortisol production
2
Q
Pathophysiology of pituitary dependant
A
Benign tumour of gland results in excessive ACTH production
Leads to increased cortisol production
3
Q
Pathophysiology of adrenal dependant
A
Associated with function adenomas or adenocarcinomas of adrenal gland
Results in excessive cortisol production
4
Q
What condition may be secondary to cushings and why
A
DM
Cortisol regulates glucose metabolism during stressful periods
Excessive production leads to prolonged hyperglycaemia
5
Q
Which is most common form of condition
A
Pituitary dependant
6
Q
Risk factors (2)
A
Excessive admin of corticosteroids
Prolonged high stress
7
Q
Clinical signs (8)
A
PUPD Involuntary night urination Increased hunger Obesity Distended abdomen Skin hyperpigmentation Flank alopecia
8
Q
Diagnosis (5)
A
Hx/cs/exam Low/high DDST ACTH stim. Abdominal ultrasound (adrenal) MRI/CT (pituitary)
