CVD Flashcards

0
Q

Atherosclerosis can lead to…

A

CHD and strokes

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1
Q

Atheroma formation can lead to …

A

Atherosclerosis

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2
Q

What happens after the endothelium becomes damaged?

A

Inflammatory response, where white blood cells mainly macrophages move into the artery wall, cholesterol also accumulates causing fatty streaks.

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3
Q

what are the characterises of an Atheroma

A

A fibrous plaque (calcium salts and fibrous tissue)

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4
Q

what happens as a result of the hardened plaque

A
The artery loses some elasticity 
The lumen becomes narrow 
Blood flow is restricted 
Increases blood pressure 
(Positive feedback)
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5
Q

What are the two types of studies when identifying risk factors

A

Cohort-prospective study a group of people are followed overtime

Case control-retrospective a group of people who have the disease are compared up those without the disease

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6
Q

What are the 3 features of a good study

A

Clear aim
Representative sample
Valid and reliable results

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7
Q

What are the CVD risk factors?

A
High blood pressure 
Obesity 
Diet/lifestyle
Smoking
Genetics 
Age
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8
Q

What is hypertension?

A

High blood pressure

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9
Q

How is blood pressure measured?

A

Using a sphygmomanometer it measures the systolic pressure and the diastole pressure in the arteries. The systolic pressure is over the diastolic pressure.

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10
Q

What is the blood pressure of a healthy person usually?

A

In a healthy person systolic pressure between 100 and 140 and a diastolic pressure of between 60 and 90

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11
Q

What are the other risk factors for CVD?

A

Salt- too much salt can cause kidneys to retain water higher fluid levels means blood pressure will increase.
Stress - increases blood pressure
Alcohol- increases blood pressure

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12
Q

How does smoking increasing the risk of developing CVD?

A

Haemoglobin- carries carbon monoxide instead of oxygen reducing the amount of oxygen that gets into cells (heart muscle is deprived)
Nicotine- stimulates the production of adrenaline which increases heart rate and the arteries and arterioles to constrict.
It also causes the platelets to become more sticky

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13
Q

3 ways of controlling blood pressure are?

A

Ace inhibitors
Calcium channel blockers
Diuretics

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14
Q

Statins are used for…..

A

reducing blood cholesterol levels

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15
Q

statins works by..

A

Inhibiting an enzyme involved in the production of LDL cholesterol or reducing the amount of lipid absorbed by the gut.

16
Q

what are the 4 types of drug treatment?

A

Anti hypertensives
Statins
Anticoagulants
Platelet inhibitory drugs

17
Q

Heart palpitations, Abnormal heart rhythms, fainting, headaches are a risk for what type of treatment

A

Anti hypertensives

18
Q

Statins can reduce the absorption of some vitamins from the gut
True of false

A

True- this is a risk

19
Q

Theses drugs can be taken in combination

A

Anti hypertensives

20
Q

Saturated fats have no …… bonds between the carbon

A

Double

21
Q

Why doesn’t unsaturated fats contain the maximin amount of hydrogen

A

As it contains double bonds