CVID – Common Variable immunodeficiency

Question 1

Common Variable immunodeficiency pathophysiology?

Answer 1

• Inability of B Cells to differentiate into plasma producing
  immunoglobin cells.

Question 2

CVID labs and symptoms

Answer 2

Normal B Cell Count , Low Ig [ A,M,G ]
– Risk of recurrent
bacterial
infection , giardiasis – espc. In IgA deficiency
*Splenomegaly

Question 3

CVID Treatment

Answer 3

IVIG

Question 4

CVID Common cause of Death

Answer 4

Lymphoma [high risk of lymphoma ]