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Kaplan: Immunology Part 1 > Cytokines Available in Recombinant Form > Flashcards

Cytokines Available in Recombinant Form Flashcards

1
Q

Clinical use of Aldesleukin (IL-2)?

A

↑ lymphocyte differentiation and ↑ NKs - used in renal cancer and metastatic melanoma

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2
Q

Clinical use of Interleukin-11?

A

↑ platelet formation - used in thrombocytopenia

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3
Q

Clinical use of Filgrastim (G-CSF)?

A

↑ granulocytes - used for marrow recovery

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4
Q

Clinical use of Sargramostim (GM-CSF)?

A

↑ granulocytes and macrophages - used for marrow recovery

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5
Q

Clinical use of Erythropoietin?

A

Anemias, especially associated with renal failure

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6
Q

clinical use of Thrombopoietin?

A

thrombocytopenia

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7
Q

Clinical use of Interferon-α?

A

Hep B and C, leukemias, melanoma

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8
Q

Clinical use of Interferon-β?

A

MS

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9
Q

Clinical use of Interferon-γ?

A

Chronic granulomatous disease → ↑ TNF

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Kaplan: Immunology Part 1 (8 decks)

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