D601-800 Flashcards
What are the four posttranslational modifications done by the Golgi apparatus?
- Phosphorylation of mannose (lysosomes only) 2. Removal of mannose residues 3. Formation of glycosylate proteins 4. Phosphorylation of sulfate amino acids
What is the epithelial cell lining the nasopharynx?
Stratified squamous nonkeratinized epithelium, which has cilia that beat toward the oropharynx.
What are the three epidermal derivatives?
- Nails 2. Hair 3. Sweat glands (both apocrine and sebaceous)
What are the long microvilli in the inner ear and male reproductive tract called?
Stereocilia
True or false? The central vein of the liver lobule is the first area affected during hypoxia.
True. Blood flows from the portal tracts (distal) to the central vein (proximal), so it is the first area affected during hypoxia.
What cell of the male reproductive system produces testosterone?
Leydig cells produce testosterone. LH stimulates Leydig cells. (Both start with L.)
Myelin is produced by which cells in the PNS? In the CNS?
In the PNS, myelin is produced by Schwann cells, in the CNS by oligodendrocytes.
What cell type of the epidermis functions as antigen-presenting cells?
Langerhans cells (found in the stratum spinosum)
What cell type is found in the peripheral white pulp of the spleen?
B cells are mainly found in the peripheral white pulp and germinal centers in the spleen.
What area of the female reproductive tract is lined by stratified squamous epithelium rich in |glycogen?
The vagina
What encapsulated lymphoid organ is characterized by presence of Hassall’s corpuscles, and absence of germinal centers and B cells?
Thymus gland. (Thymus gland is essential for T cell maturation.)
What cell transports IgA, is secreted by plasma cells, and is in Peyer’s patches to the gastrointestinal lumen?
M-cells
What are the cells of the parathyroid gland that produce PTH?
Chief cells
What skin type on the palms and soles is characterized by the absence of hair follicles and presence of stratum lucidum?
Thick skin
What is the name of hydrophilic pores that allow the direct passage of ions and particles between two adjacent cells?
Gap junctions
What type of lysosome is formed when lysosome fuses with a substrate for breakdown?
Secondary lysosome (think of the primary as inactive and secondary as active)
What cell membrane structure increases the surface area of a cell and has actin randomly assorted within its structure?
Microvillus
What are the four components of the basement membrane?
- Laminin 2. Heparan sulfate (heparitin sulfate) 3. Fibronectin 4. Type IV collagen
What organelle synthesizes proteins that are intended to stay within the cell?
Free polysomes. Membrane-associated polysomes are the site of protein synthesis destined to leave the cell.
What cell type of the body or fundus of the stomach secretes IF?
Parietal cells (Remember, they secrete HCl, too.)
What cell type of the body or fundus of the stomach secretes pepsinogen?
Chief cells
What hormone, produced by the granulose cell, stimulates the endometrium to enter the proliferative phase?
Estrogen; the first 14 days of the female reproductive cycle mark the proliferative phase.
What cells of the nephron function as sodium concentration sensors of the tubular fluid?
Macula densa
What type of chromatin is transcriptionally active?
Euchromatin, the dark stuff in the nucleus on an electron microscope image.