Day 1: MSK, GI, cards, neuro Flashcards

(1277 cards)

1
Q

What are T1 bright substances in imaging?

A

Fat and hemorrhage

Fat saturation sequences are used to differentiate between them.

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2
Q

What is a lymphatic malformation characterized by?

A

Complex cystic solid structure

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3
Q

What condition is associated with nodules in the trachea and small cystic/solid nodules in lower lobes?

A

Tracheobronchial papillomatosis

Usually due to HPV, often acquired during birth.

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4
Q

What mutation is associated with a poor prognosis in midline glioma?

A

H3K27 mutation

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5
Q

What could a hyperechoic renal mass on ultrasound be?

A

Angiomyolipoma or renal cell carcinoma

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6
Q

What does a progressively enhancing intrahepatic mass with central enhancement indicate?

A

May represent:
* Intrahepatic cholangiocarcinoma (solitary mass with infiltrating margins and associated intrahepatic biliary ductal dilatation)
* Epithelioid hemangioendothelioma (usually composed of multiple peripheral masses)
* Hepatocellular carcinoma (arterial enhancement, washout on delayed phases )

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7
Q

What is the imaging feature of pheochromocytoma?
and what nuc study

A

Extremely high T2 signal adrenal lesion
MIBG for adrenal
(Ind 111 pentetreotide for extra adrenal)

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8
Q

How does myelolipoma appear on fat suppression images?

A

Hypointense

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9
Q

What are the key features of adenomyosis?

A

Uterine enlargement, irregular margins of endometrial myometrial interface, diffuse heterogeneity including microcyst formation

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10
Q

What is the most common extratesticular neoplasm?

A

Lipoma

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11
Q

What is the most common neoplasm of the epididymis?

A

Adenomatoid tumor

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12
Q

What type of tumor has the best prognosis in osteosarcoma?

A

Parosteal osteosarcoma

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13
Q

Where does parosteal osteosarcoma typically occur?

A

On long bone metaphyseal surface

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14
Q

What is the most common subtype of liposarcoma?

A

Well differentiated liposarcoma

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15
Q

Where does chondroblastoma typically occur?

A

Epiphysis or apophysis of skeletally immature patient, eccentric

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16
Q

What are the two types of femoroacetabular impingement and their associations?

A

CAM type and Pincer type
CAM associated with non spherical femoral head
Pincer associated with acetabula protrusio

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17
Q

What is another name for tenosynovial giant cell tumor and what does it feature?

A

Pigmented villonodular synovitis (PVNS)
contains hemosiderin

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18
Q

What is the earliest sign of impending articular surface collapse in avascular necrosis?

A

Crescent sign

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19
Q

What does thymic rebound appear as on imaging? And in what patients

A

Chevron pattern over mediastinum in post chemo patients

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20
Q

What is the most common type of benign and malignant cardiac tumor?

A

Myxoma is benign, sarcoma/angiosarcoma is malignant

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21
Q

What does CPT stand for in medical terminology?

A

Current Procedural Terminology

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22
Q

What is SNOMED clinical terms used for?

A

Computer processable terms for clinical documentation and reporting

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23
Q

What does ICD stand for and what is it used for?

A

International Classification of Diseases for diagnosis for patient encounters

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24
Q

What does DRG stand for and what is it used for?

A

Diagnosis Related Group for inpatient hospital service insurance billing

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25
What imaging feature is associated with neurocysticercosis?
Starry sky appearance multifocal parenchymal calcifications
26
What is a characteristic of Sturge-Weber syndrome?
Focal parenchymal atrophy calcifications usually peripheral and curvilinear/gyriform with tram tracks
27
What are the features of biliary atresia?
Jaundiced neonate/hyperbilirubinemia, abnormal gallbladder, echogenic triangular cord due to fibrosis ## Footnote Treatment involves kasai portoenterostomy and is associated with congenital anomalies like heterotaxy and malrotation.
28
What type of bone does Ewing sarcoma typically involve?
Flat or tubular bones, with permeative pattern
29
Which cranial nerve is superior most within the lateral dural wall of the cavernous sinus?
Oculomotor (CN3)
30
Which cranial nerves follow the oculomotor nerve in the lateral wall of the cavernous sinus?
Trochlear (CN4), ophthalmic division of trigeminal (CNV1), maxillary division of trigeminal nerve (CNV2) Abducens is within cavernous sinus itself with carotid artery
31
What are the divisions of the trigeminal nerve?
CN5 1) ophthalmic 2) maxillary 3) mandibular
32
what is the gallbladder ghost triad seen in and what is it? how is it treated
Biliary atresia Less than 19 mm, irregular margins, discontinuous echogenic wall kasai portoenterostomy
33
Which of the following is the correct definition of an isobar?
Same atomic mass but different number of protons
34
Where does the piriformis muscle originate?
Anterior sacrum ## Footnote The piriformis muscle is a small muscle located in the gluteal region.
35
Where does the piriformis muscle insert?
Greater trochanter of the femur ## Footnote The greater trochanter is a prominent bony projection on the femur.
36
What is the unit of radioactivity?
The becquerel (Bq) or the curie (Ci) ## Footnote 1 Ci = 3.7 x 10^10 Bq and 1 Bq = 1 disintegration per second
37
Fill in the blank: 1 Ci = _______ Bq.
3.7 x 10^10
38
True or False: 1 Bq represents one disintegration per minute.
False
39
What does 1 Bq measure?
1 disintegration per second
40
What is best next imaging study for patient with monoarticular hip disease and radiograph showing effusion and subchondral cysts
MRI without contrast to assess for pigmented villonodular synovitis vs osteochondromatosis
41
What do recommended discharge criteria suggest regarding the level of consciousness?
The level of consciousness should return to acceptable levels for a period of 2 hours from the time of administration of the reversal agent ## Footnote This criterion is important to ensure patient safety before monitoring ends.
42
How long should vital signs be monitored after administration of the reversal agent?
Vital signs should return to acceptable levels for a period of 2 hours ## Footnote Monitoring vital signs is crucial for assessing the patient's recovery.
43
Fill in the blank: Recommended discharge criteria suggest that the level of consciousness and vital signs should return to acceptable levels for a period of _______ from the time of administration of the reversal agent.
2 hours
44
True or False: Monitoring ends immediately after the administration of the reversal agent.
False ## Footnote Monitoring continues for 2 hours to ensure safety.
45
What are the national patient safety goals mandated by the Joint Commission to improve patient safety and reduce risk of errors
-reporting of critical results in a timely manner -use of at least 2 patient identifiers -‘time-out' before ALL procedures -compliance with evidence-based hand-hygiene guidelines
46
What does a rising PSA level usually prompt in patient with previously treated prostate cancer?
A bone scan ## Footnote If PSA <20, rules out osseous mets
47
What does CPAM stand for?
Congenital pulmonary airway malformation ## Footnote CPAM is a developmental abnormality of the lungs.
48
What type of tissue proliferation is associated with CPAM?
Hamartomatous proliferation of small airways ## Footnote This proliferation connects with the bronchial tree and forms cysts.
49
What is the blood supply source for CPAM?
Pulmonary circulation ## Footnote This indicates that the blood supply is derived from the lungs.
50
What characterizes sequestration in the lungs?
Aberrant lung tissue with systemic blood supply ## Footnote This means that the affected lung tissue receives blood from systemic circulation instead of the pulmonary circulation.
51
Where is sequestration typically located?
Left lower lobe ## Footnote This is the most common site for lung sequestration.
52
What imaging characteristic may indicate lung sequestration?
Echogenic mass at left lung base ## Footnote This finding can help in the diagnosis of sequestration.
53
Sequestration can sometimes be found in which anatomical location and what can it mimic?
Subdiaphragmatic (Can mimic adrenal mass)
54
what exits through the superior orbital fissure
ophthalmic division of trigeminal (CNV1) trochlear (CN4) and abducens (CN6) nerves
55
what exits through the inferior orbital fissure/foramen rotundum
maxillary division of the trigeminal CNV2
56
what exits through the foramen ovale and spinosum
mandibular division of the trigeminal (CNV3) with accessory meningeal artery middle meningeal artery
57
what is the order within the internal auditory canal
7 up coke down facial (CN7) and cochlear (CN8) are anterior to superior and inferior vestibular nerves (CN8)
58
what exits through the jugular foramen
glossopharyngeal (CN9) in the pars nervosa and vagus (CN10) and spinal accessory (CN11) in the pars vascularis
59
features of NF1
-nonspecific T2/Flair bright parenchymal foci typically in globes pallidus and cerebellar hemisphere -juvenile pilocytic astrocytoma -optic nerve gliomas -hamartomas of eye (lisch nodules) -neurofibromas -skin nodules, cafe au lait spots (peri areolar breast nodules)
60
features of NF2
multiple schwannomas, meningiomas, and ependymomas bilateral vestibular schwannomas
61
features of PHACES
posterior fossa malformations hemangiomas arterial cerebrovascular anomalies cardiac defects eye abnormalities sternal/ventral defects
62
What is the appropriate area of coverage needed in a contrast-enhanced CT for a patient who presents with right vocal cord paralysis? Left vocal cord paralysis?
Skull base to clavicles Skull base to left pulmonary artery for left recurrent laryngeal nerve
63
aminophylline
nonselective adenosine receptor antagonist
64
granulomatosis with polyangiitis
wegener granulomatosis: nasal septal perforation/erosion and sinusitis solid and cavitated pulmonary nodules septic emboli
65
features of round atelectasis
comet tail sign (curved pulm vessels and bronchi) must contact pleura pleural abnormality
66
where are artery, veins, bronchus, and lymphatics located in lung
intralobular: artery and bronchus interlobular: vein and lymphatics
67
What is groundglass consolidation associated with in the central region?
edema, hemorrhage, pcp, alveolar proteinosis ## Footnote PCP stands for Pneumocystis pneumonia, a type of lung infection caused by a fungus.
68
What conditions are related to groundglass consolidation in the peripheral region?
Organizing pneumonia, chronic eosinophilia pna, atypical/viral pna, edema ## Footnote Organizing pneumonia is a type of lung inflammation that leads to the formation of granulation tissue in the alveoli.
69
What does interlobular septal thickening indicate?
edema, alveolar proteinosis, hemorrhage, pcp ## Footnote Interlobular septal thickening can be a sign of various lung conditions, often related to fluid accumulation.
70
Which conditions are associated with nodular groundglass consolidation?
lymphangitic carcinomatosis, sarcoid ## Footnote Lymphangitic carcinomatosis refers to the spread of cancer through the lymphatic system.
71
What is crazy paving associated with?
alveolar proteinosis, pcp, organizing pna, bronchioalveolar carcinoma, hemorrhage, ards ## Footnote ARDS stands for Acute Respiratory Distress Syndrome, a severe lung condition.
72
What conditions are indicated by centrilobular nodules?
TB or atypical mycobacteria/mycoplasma pna, hypersensitivity pneumonitis, hot tub lung, RB-ILD, silicosis ## Footnote Tb refers to Tuberculosis, an infectious disease that primarily affects the lungs.
73
What are perilymphatic nodules associated with?
sarcoid, pneumoconioses, lymphangitic carcinomatosis ## Footnote Pneumoconioses are a group of lung diseases caused by inhaling various types of dust.
74
What presents with 'random nodules'?
Hematogenous mets, septic emboli, pulmonary langerhans cell histiocytosis ## Footnote Hematogenous mets refer to metastases that spread through the bloodstream.
75
what presents as lower lobe fibrosis
-UIP: basal predominant honeycombing -NSIP: basal predominant groundglass w sub pleural sparing and without honeycombing -asbestosis: pleural effusions and plaques -panlobular/acinar emphysema -rheumatoid
76
what presents with upper lobe fibrosis
inhalation, silicosis, coal workers Cystic fibrosis, RBILD sarcoid Ank spondy
77
What does the hepatic venous waveform look like and its components?
atrial contraction (away from heart toward liver/above baseline) ventricular systole (move toward heart) atrial overfilling (direction aligns with heart) tricuspid valve opening
78
What condition is characterized by tree-in-bud nodules and bronchiectasis of the right middle lobe or lingula?
MAC/lady windermere
79
What are the radiological findings associated with asbestosis?
Irregular inter and intralobular septal thickening * Subpleural curvilinear opacities * Parenchymal bands * Peripheral and posterior lower lung zones
80
What is the reverse halo sign associated with?
AKA Atoll sign Cryptogenic organizing pneumonia (COP) ## Footnote Consolidative ring surrounding central groundglass
81
What does the halo sign look like and indicate?
characterized by groundglass halo surrounding consolidation Invasive aspergillus ## Footnote The halo sign is a radiological feature often seen in cases of invasive aspergillosis.
82
What does LIP appear as what is it associated with
Diffuse or lower lobe ground glass with perivascular cysts Sjogren or HIV ## Footnote This description may indicate specific pathological findings in lung imaging.
83
What is hypersensitivity pneumonitis characterized by?
Air trapping, mosaic attenuation, centrilobular nodules ## Footnote Hypersensitivity pneumonitis is an inflammatory response in the lungs due to inhaled organic antigens.
84
What imaging findings are associated with RB-ILD?
Ground glass and centrilobular nodules in the upper lung and smoking ## Footnote RB-ILD stands for Respiratory Bronchiolitis Interstitial Lung Disease, often seen in smokers.
85
What are the key features of pulmonary Langerhans cell histiocytosis? what does it spare? who does it affect?
Upper lobe predominant bizarre irregular cysts and cavitary nodules, spares costophrenic recesses young adults who smoke.
86
what presents with eggshell calcifications of the lymph nodes
silicosis, sarcoid, coal workers pneumoconiosis
87
What are the conditions associated with low attenuation lymph nodes?
* Active tuberculosis * Fungal infection * Lymphoma * Mets (squamous cell) ## Footnote 'Mets' refers to metastatic disease.
88
Which conditions are characterized by avid lymph node enhancement?
* Castleman disease * Sarcoidosis * Tuberculosis * Vascular Mets ## Footnote 'Vascular Mets' refers to vascular metastases.
89
What types of cancers are included in hypervascular Mets?
* Renal cell carcinoma) * Thyroid (papillary) * Lung * Breast * Melanoma * Neuroendocrine * Choriocarcinoma
90
What is the characteristic imaging phase for hepatic metastases?
Hypovascular so best on portal venous phase ## Footnote Hepatic metastases typically show decreased vascularity, making the portal venous phase ideal for assessment.
91
What are the imaging characteristics of hepatocellular carcinoma (HCC) and serum marker?
Enhances on arterial and washout with local venous invasion AFP elevated
92
What is the imaging feature of a hemangioma?
Discontinuous progressive peripheral nodular enhancement ## Footnote No internal Doppler flow
93
What are key imaging features of focal nodular hyperplasia (FNH)?
Central stellate scar Avid enhancement and washout Isoechoic with spoke wheel vessels Positive on sulfur colloid
94
What is positive in the liver on HIDA scan
FNH (compared to adenoma) ## Footnote FNH has functional bile ducts that can be visualized on HIDA scans, which is not the case for adenomas.
95
What demographic is commonly associated with hepatic adenomas? what features are found in hepatic adenomas
Women on birth control Fat or hemorrhage Cold on sulfur colloid scan
96
features of Budd chiari
Venous outflow obstruction with edematous liver Sparing of caudate bc direct ivc drainage Nodular regenerative hyperplasia
97
What are the types of choledochal cysts? what is done with them
1) Fusiform CBD 2) Saccular CBD 3) Duodenal 4) Multiple 5) Intrahepatic/Caroli (with central dot sign) resected due to cholangiocarcinoma risk
98
What is seen with ascending cholangitis?
Obstruction of biliary tree, likely choledocholithiasis Charcots triad Thickening and hyperenhancement bile duct walls ## Footnote Ascending cholangitis is often caused by gallstones blocking the bile duct.
99
What are the components of Charcot's triad?
Fever, abdominal pain, jaundice ## Footnote Charcot's triad is a classic presentation of ascending cholangitis.
100
What is primary sclerosing cholangitis? what are the characteristic imaging findings
Idiopathic inflammation, fibrosis, and destruction of bile ducts Beaded intrahepatic ducts and CBD Associated with UC and men Looks similar to aids cholangiopathy but with papillary stenosis
101
How does primary biliary cirrhosis differ from primary sclerosing cholangitis?
Inflammation and destruction of smaller bile ducts Middle-aged women with pruritus Lace like fibrosis Antimitochondrial antibodies Regenerative and dysplastic nodules
102
What is a biliary cystadenoma?
Large multiloculated cystic mass with enhancing septations in middle aged women If nodular solid enhancing component-> cystadenocarcinoma
103
What does cholangiocarcinoma result in and its causes
Hilar tumor (Klatskin) Results in intrahepatic ductal dilatation Chronic biliary disease in US Liver fluke
104
What are the solid pancreas tumors? how is the most common one characterized
Adenocarcinoma and acinar carcinoma ## Footnote Adenocarcinoma characterized by the double duct sign, Sma encasement, venous invasion, and metastasis are typically unresectable.
105
What are the key features of acinar carcinoma?
solid tumor Aggressive, affects elderly males, associated with lipase hypersecretion syndrome
106
What is a serous cystic neoplasm also known as and characterized as?
Cystadenoma (grandmother lesion) It is characterized by multiple small cysts and a stellate central scar and calcification. typically in the head
107
What is the mucinous cystic neoplasm?
mother lesion Typically presents as unilocular with a capsule, usually located in the body and tail of the pancreas has malignant potential
108
What distinguishes solid and papillary epithelial tumors?
Daughter lesion Large mass with solid and cystic areas, thick capsule, hemorrhage present Malignant
109
What is an intraductal papillary mucinous neoplasm (IPMN) known for?
Grandfather lesion Malignant potential
110
Fill in the blank: The double duct sign is associated with _______.
Adenocarcinoma ## Footnote This sign indicates the involvement of both the pancreatic and bile ducts.
111
True or False: Mucinous cystic neoplasms are typically found in the head of the pancreas.
False ## Footnote They are usually located in the body and tail of the pancreas.
112
What type of pancreas tumor is characterized by multiple small cysts?
Serous cystic neoplasm ## Footnote Also known as cystadenoma.
113
What is a common demographic characteristic of acinar carcinoma?
Elderly males ## Footnote This type of tumor has a high incidence in older male patients.
114
VHL associated with
hemangioblastoma w drop mets Clear cell rcc serous cystadenoma pancreatic neuroendocrine
115
What can present with fatty atrophy of pancreas What are their characteristics
cystic fibrosis with fibrosing colonopathy and congenital abscence of vas deferens Schwachman diamond (inherited disorder with childhood pancreatic atrophy, diarrhea, short stature, eczema)
116
sausage shaped pancreas
autoimmune pancreatitis
117
How does spleen hemangioma appear on CT and MRI?
Hypoattenuating and hyperenhancing. T2 bright
118
What is Kasabach Merritt syndrome.
spleen hemangioma or liver hemangioma associated with anemia, thrombocytopenia, and coagulopathy
119
What is Klippel Trenaunay Weber syndrome?
spleen hemangioma associated with cutaneous hemangiomas Port wine nevi varicose veins/venous malformation extremity hypertrophy (localized gigantism)
120
What does a spleen hamartoma appear as and what is it associated with?
Hypoattenuating mass with heterogeneous enhancement. associated with tuberous sclerosis
121
how does splenic lymphoma appear
hypoenhancing POST CONTRAST on CT and MRI
122
triplane fracture vs juvenile tillaux
*Coronal plane through metadiaphysis* Horizontal plane through lateral and anterior physis Sagittal plane through epiphysis
123
fibroid imaging features
T2 dark, variable T1 enhancing
124
contrast progression through tubes during salpingogram
intramural->ostium->isthmus->ampulla->infundibulum-> ovary/free spill
125
what agent is dotatate and what is it used for
somatostatin binding agent neuroendocrine tumors
126
what are the characteristics of giant cell tumors how do they appear on MRI
eccentric lytic epiphyseal lesion arising from metaphysis and crossing closed epiphyseal plate in skeletally mature patients low signal T2 Associated with paget disease or hyperparathyroidism
127
what is the most common retroperitoneal tumor order of retroperitoneal spaces anterior to posterior
liposarcoma Anterior pararenal, gerotas fascia, perirenal space, zuckerkandls fascia, posterior pararenal space
128
What is the positioning of vacuum assisted tip in breast biopsy?
The vacuum assisted tip should be past the lesion so that it can fall into the aperture ## Footnote This is in comparison to spring-loaded techniques.
129
What are the malignant potentials of PASH and complex sclerosing lesion?
PASH is benign without malignant potential CSL/radial scar is benign with upgrade potential-> must be surgically excised (appears as spiculated mass or architectural distortion)
130
What syndrome is associated with breast hamartoma?
Cowden syndrome Fat and glandular tissue "Breast within breast"
131
What is Mondor's disease? Which vein is most commonly involved in Mondor's disease?
Superficial thrombophlebitis, most commonly from superficial epigastric vein Beaded tubular structure
132
proper positioning on MLO view
-Pec muscle is widened at axilla and extend to nipple, convex anterior margin -Breast pulled up and out -Infra-mammary fold open on MLO and neutral on CC -Small amount of belly should be visible on MLO -1 cm difference on posterior nipple line on MLO and CC
133
when start screening in patient with Known genetic mutation or lifetime risk ≥ 20%
MG annually starting at age 30 MRI annually starting at age 25-30
134
when start screening in patient with breast cancer history
MG and MRI annually starting at the time of diagnosis
135
when start screening in patient with hx of chest radiation therapy before age 30
MG annual at age 25 or 8 years after radiation MRI annually starting at age 25-30
136
when start screening in patient with hx of ALH, ADH, or LCIS
MG and MRI annually starting at the time of diagnosis
137
What is Addison disease?
Chronic insufficiency due to autoimmune destruction or sequela of infection
138
What causes Waterhouse-Friderichsen syndrome?
Post hemorrhagic failure due to Neisseria meningitidis ## Footnote This condition is often associated with severe adrenal gland hemorrhage.
139
What is the characteristic feature of an adrenal adenoma?
Lipid rich, less than 10 HU (drop out mri) and greater than 60% washout
140
What is an adrenal myelolipoma?
Presence of macroscopic fat
141
What progression of ductal breast pathology?
normal>FEA>ADH>DCIS>IDC ## Footnote Flat Epithelial Atypia
142
What is the most common type of invasive carcinoma and its prognosis?
Invasive Ductal Carcinoma Not Otherwise Specified (IDC NOS) is the most common and has the worst prognosis compared to special types.
143
What characterizes Ductal Carcinoma In Situ (DCIS)?
DCIS is a clonal proliferation of malignant epithelial cells originating in the terminal ductal lobular unit of the breast without invasion of the basement membrane.
144
What is the progression of lobular carcinoma?
Normal > atypical lobular hyperplasia (ALH) > lobular carcinoma in situ (LCIS) > invasive lobular carcinoma (ILC).
145
Describe the cellular characteristics of invasive lobular carcinoma. how does it compare to IDC
-Dark star, shrinking breast, shadowing on US -Presents later in life/older than IDC -more likely to be bilateral, multifocal, and multicentric -without calcifications
146
What are the common mammographic mass margins?
* Circumscribed * Obscured * Microlobulated * Indistinct * Spiculated
147
What are the categories of mammographic density?
* Fat * Low * Equal * High
148
What shapes can mammographic masses take? Ultrasound masses?
(ROI) * Round * Oval * Irregular
149
What is the difference between asymmetry and focal asymmetry in mammography? what is developing asymmetry
Asymmetry is seen in a single view, while focal asymmetry is seen on two projections. Developing asymmetry indicates an increase in size.
150
What does global asymmetry refer to?
Global asymmetry refers to one breast appearing more dense compared to the other.
151
appearance of IDC and ILC on ultrasound
ILC well differentiated with posterior shadowing IDC poorly differentiated with posterior acoustic enhancement
152
Benign birads 2 calcifications
-Popcorn calcs= involuting fibroadenoma -Large rod like/secretory= pointing towards nipple, duct etasia -Milk of calcium= free floating calcium in cysts -Dystrophic calcs= geometric calcs related to fat necrosis -Round -egg-shell/rim calcs= fat necrosis
153
Intermediate birads 4 calcs
-Amorphous/indistinct: “powdered sugar”; suspicious if clustered/grouped, linear or segmental -Coarse heterogeneous= “dull tip”; irregular, smaller than dystrophic, >0.5 mm
154
Higher suspicion birads 4/5 calcs
-Fine pleomorphic: “sharp tip”; dot-dash -Fine linear or branching: “sharp tip”
155
Architectural distortion
Radiating linear densities emanating from central point Tethering of normal fibroglandular tissue
156
suspicious vs benign breast US findings
suspicious: hypoechoic with posterior shadowing, hyperechoic halo (can also be seen in abscess) benign: hyperechoic
157
What is a galactocele? Where is it located
Cystic collection of milk, typically subareolar ## Footnote Characterized by fat fluid level, and appears as a well circumscribed macrolobulated mass.
158
Describe the characteristics of a fibroadenoma.
Palpable mass in young women Popcorn calcifications in older women Homogenous hypoechoic, circumscribed parallel oval with hyperechoic fibrous bands
159
What is the most common cause of nipple discharge? how does it appear? what to do with it
Intraductal papilloma Appears as a round or oval circumscribed mass in the subareolar region, isochoic on ultrasound, and may be located within the duct. surgical excision
160
What is a phyllodes tumor and what does it look like? What to do with it
Large and rapidly growing tumor that can recur Oval or lobular circumscribed mass with heterogeneous echotexture Require wide surgical excision (some are benign and others malignant)
161
What is a characteristic feature of tubular carcinoma?
Small irregular spiculated mass
162
What imaging characteristic is associated with mucinous carcinoma?
T2 hyperintense mucin and progressive enhancement
163
T2 hyperintense breast lesion with enhancement
Large: angiosarcoma (Primary or secondary to prior breast conservation therapy and radiation) multiple circumscribed: RCC or melanoma mets
164
breast MRI features
focus: enhancement without precon correlate, <5 mm non mass like enhancement: clustered ring enhancment suggestive of malignancy; clumped enhancement suggestive of DCIS
165
appearance of breast implant types
saline: denser rim with folds and valve silicone: homogeneous density throughout
166
intracapsular rupture signs
linguini sign, salad oil sign on mri Step ladder sign on US
167
fibrocystic change is most common in
premenopausal women
168
lymphangioleiomyomatosis
thin walled cysts chylothorax
169
fourth ventricle lesions in peds
ependymoma (like toothpaste, squeeze through foramen luschka/magendie, calcs) medulloblastoma (roof, diffusion restriction, avid enhance, necrosis and calcs) pilocytic astrocytoma (NF1)
170
fourth ventricle lesion in adults
subependymoma (no enhancement) hemangioblastoma metastases
171
F18 FDG pet glucose level
should be less than 200 NPO for 4 hrs prior to exam
172
FDG F18 PET normal distribution
brain Liver Ovaries Muscle concentrated in urine
173
FDG F18 PET is not useful for
HCC, RCC, prostate bronchioloalveolar cell carcinoma or carcinoid/neuroendocrine
174
myocardial stress/"exercise" agents
-adenosine: contraindicated in asthma, COPD, caffeine use -regadenoson (adenosine agonist) -dipyridamole (adenosine deaminase inhibitor): aminophylline is antidote -dobutamine (beta 1 agonist): used when adenosine is contraindicated
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myocardial perfusion agents
-Tc99 sestamibi: perfusion at the time of injection -rubidium82: half life 75 s -N13 ammonia: half life 10 m
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myocardial imaging to assess
-acute chest pain -hemodynamic significance of coronary stenosis -post MI risk stratification -viability prior to revascularization -surgery preop risk assessment -post CABG revascularization
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fixed myocardial perfusion defect on stress and rest
either hibernating myocardium or scar -> FDG PET uptake=hibernating myocardium -> if no FDG PET uptake= nonviable scar
178
what does cardiac ischemia look like on perfusion
perfusion defect on stress imaging which is reversible on rest
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dilation of the left ventricle present on stress imaging
transient ischemic dilation= three vessel disease
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gold standard for myocardial viability
F18 FDG PET (but cannot evaluate perfusion) Thallium can evaluate viability (hibernating vs scar post redistribution) and perfusion but dose is too high and half life too long
181
thyroid imaging with what agents
Tc99 pertechnetate, I123 and I131 I123: shorter half life and pretty picture but expensive I131: long half life and ugly picture, cheap Tc99m: trapped but not organified
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graves looks like
hyper thyroid: thyromegaly, diffusely increased activity, visualization of the pyramidal lobe
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Hashimoto looks like on pet
mostly hypothyroid: thyromegaly, patchy increased activity
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thyroiditis looks like
Subacute or de Quervain silent OR swollen and painful decreased uptake Hyperthyroid then hypothyroid
185
parathyroid imaging
Tc99m sestamibi thyroid washes out, remaining parathyroid adenoma
186
Tc99m sulfur colloid scan of liver demonstrates
photopenic defect: cyst decreased uptake: HCC, adenoma, abscess increased uptake: FNH, regenerative nodule, Budd chiari
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colloid shift on sulfur colloid scan
liver dysfunction (cirrhosis) increased uptake in spleen and bone marrow
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what radionuclide for meckel scan?
Tc99 Pertechnetate omphalomesenteric duct remnant located in distal ileum w gastric mucosa which can bleed
189
HIDA requirements
NPO 6 hrs, but has eaten in 24 hrs
190
HIDA visualization
liver in 5 min, gallbladder in 15 min if no visualization, morphine to contract sphincter of oddi
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acute chole on HIDA
no visualization of gallbladder after morphine admin or rim sign (increased hepatic activity at the fossa)
192
Ventilation scan performed with
Xenon 133 (inhaled gas, performed first) or Tc 99m DTPA (aerosol)
193
V/Q perfusion scan performed with? when contraindicated? right to left shunt?
Tc 99m MAA severe pulmonary hypertension immediate renal and brain uptake
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bone scan agent: what phases:
Tc99m MDP (chemisorption) Blood flow, blood pool, delayed
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what is positive on all 3 phases of bone scan? positive 2 phases? double density sign?
3: fracture, osteomyelitis, septic arthritis 2: cellulitis (non positive on delayed) dd: osteoid osteoma
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Tc99m MDP superscan looks like and due to
diffusely increased osseous uptake hyperparathyroidism or metastatic prostate cancer
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osseous Paget on bone scan and xray
lytic lesions are positive on bone scan sclerotic lesions are positive on X-ray
198
renal nuc agents and what they evaluate
Tc99m DMSA: cortical agent for scarring/pyelonephritis Tc99m DTPA: GFR and perfusion Tc99m MAG3: renal plasma flow and perfusion (diuretic renogram with lasix for obstruction)
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evaluate pediatric reflux
radionuclide cystography Tc99m pertechnetate, Tc99m DTPA, Tc99m SC
200
Thallium and gallium diseases
Kaposi sarcoma: thallium avid tuberculosis: gallium avid lymphoma: both avid
201
I123 MIBG vs I111 pentetreotide
I123: primary pheochromocytoma, neuroblastoma I111: extra adrenal pheo, carcinoid
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gallium 67 MOA and uses
binds transferrin (inflam, infection, neoplasm) -first line spinal osteomyelitis -panda sign and lambda: sarcodiosis -pcp and pneumonia
203
WBC imaging
spleen>liver>bone marrow In111 WBC Tc99m HMPAO (physiologic GI/GU and renal uptake)
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crossed cerebellar diaschisis
supratentorial lesion decreased radio tracer uptake of CONTRALATERAL cerebellum interrupted corticopontine pathways
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RCC types
-clear cell: (most common, hypervascular) Von hippel lindau vhl cystic w enhancing part -papillary: (hypovascular) transplant -chromophobe: (best prognosis) birt hogg dube -medullary: (aggressive) sickle cell -translocation: kids w prior chemo
206
renal angiomyolipoma composition and appearance
macroscopic fat, muscle, and blood vessels risk of hemorrhage avid enhancement hyperechoic WITHOUT calcifications (think Rcc otherwise)
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oncocytoma apperance
central scar homogeneous enhancement Spoke wheel vascular pattern on US
208
von hippel lindau vhl
AD -Clear cell RCC, pheochromocytoma -CNS hemangioblastoma -pancreatic neuroendocrine tumor -Serous cystadenoma -renal, liver, pancreatic cysts and epididymal cysts
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birt hogg dube
chromophobe RCC, lung cysts, fibrofolliculomas AD
210
tuberous sclerosis
AD -cortical tubers, subependymal nodules, SE giant cell astrocytoma (foramen of monro w homogenous enhancement) -cystic lung LAM and chylothorax -cardiac rhabdomyoma -bilateral AMLs, renal cysts, rccs
211
multilocular cystic nephroma
Michael Jackson lesion (young boys and middle age women) herniate into renal pelvis Thick fibrous capsule w enhancing septa
212
acquired cystic kidney disease associated with
AKA uremic cystic disease dialysis and increased risk of RCC (compared to ADPKD)
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xanthogranulomatous pyelonphritis what associated sign and micro
chronic renal obstruction 2/2 obstructive calculi bear paw sign: fatty replacement of parenchyma proteus mirabilis and e coli
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what is putty kidney and what is it associated with
calcified atrophic kidney with scarring and necrosis autonephrectomy in end stage renal tuberculosis
215
molar tooth sign seen where
extraperitoneal bladder rupture in space of retzius (conservative management vs surgery in intraperitoneal rupture) Joubert syndrome in brain
216
male urethra anatomy
prostatic (transitional)->membranous->bulbous->penile (squamous)->fossa navicularis
217
urethral glands
male: cowpers glands in the membranous urethra female: paraurethral skene glands
218
bph vs prostate adenocarcinoma location and appearance
bph transitional zone adeno in peripheral zone (T2 dark, diffusion restriction, early enhancement/washouts)
219
prostate staging
T1 only on biopsy, T2 confined to prostate, T3 extend through capsule and to seminal vesicles, T4 invades adjacent structures N1 nodal involvement M0 no met, M1 extra pelvic mets
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uterus MRI appearance
endocervical canal T2 bright junctional zone T2 dark myometrium intermediate
221
adenomyosis MRI features
thickening of myometrium/junctional zone (T2 dark) with ectopic endometrial gland small t2 hyperintense foci
222
endometriosis MRI features and next step
tiny T1 hyperintense foci (hemorrhagic implants) T1 bright (light bulb bright) endometrioma w T2 shading ->laparoscopy
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fibroid MRI and US appearance what can't UAE treat
T1 and T2 hypointense, with enhancement hypoechoic with venetian blin UAE not effective for necrotic or hemorrhagic fibroids
224
endometrial carcinoma MRI appearance and stages
T2 hypointense, hypoenhancing 1) confined to uterus, 2) spread to cervix, 3) spread to adnexa, vagina, nodes, 4) spread to bladder/bowel
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cervical carcinoma stages and significance
1) confined to uterus/cervix 2a) spread to upper vagina 2b) parametrial invasion (NON surgical) 3a) spread to lower vagina 3b) pelvic sidewall or node 4) bladder or rectum
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uterine anomalies
separate fundi (failure to fuse with fundal cleft): didelphys->bicornuate-> single external fundus (failure to cleave): septate->arcuate
227
dermoid cyst
mature cystic teratoma T1 bright (like endometrioma) but fat sat lesions rokatinsky nodule: hair, teeth
228
ovarian metastases from where
gastric (krukenberg), colon, pancreas, breast
229
where is CSF produced and reabsorbed
choroid plexus: lateral ventricle body to temporal horns, roof of third and fourth ventricles arachnoid granulations
230
flow of CSF
frontal horn-> body-> atrium-> occipital and temporal horns lateral ventricles-> foramen of monro-> third-> cerebral aqueduct-> fourth-> luschka and magendie, obex to canal
231
What is cytotoxic edema?
Damaged NaK ATPase ion pumps leading to cell death, primarily affecting gray and white matter interface in infarct leading to an imbalance of ions and water influx into cells
232
What causes vasogenic edema?
Increased capillary permeability due to neoplasm, infection, or infarct, primarily affecting white matter conditions that disrupt the blood-brain barrier, allowing fluids to accumulate in the extracellular space.
233
What is interstitial edema?
Cerebrospinal fluid flow imbalance, as seen in obstructive hydrocephalus resulting in transependymal/periventricular flow ## Footnote Interstitial edema can occur due to conditions that block normal CSF flow, leading to fluid buildup in brain interstitial spaces.
234
What is subfalcine herniation and what are the consequences
Cingulate gyrus herniation under the falx cerebri * ACA compression leading to infarct * Contralateral hydrocephalus due to foramen of Monro obstruction
235
What is transtentorial herniation?
Uncal herniation Herniation of the medial temporal lobe
236
What are the effects of transtentorial herniation?
* PCA/SCA compression (ptosis and pupil dilation) * Ipsilateral CN3 compression causing oculomotor dysfunction * Shearing of perforating basilar branch vessels leading to upper brainstem Duret hemorrhages * Contralateral cerebral peduncle compression causing hemiparesis
237
What is cerebellar tonsillar herniation? What is prone to herniation and what can it lead to
Herniation of the cerebellar tonsils due to limited volume in the posterior fossa cerebellar infarcts are prone to herniation can cause compression of the medulla
238
What is communicating hydrocephalus? and what are examples
AKA Non-obstructive hydrocephalus Extraventricular hydro 2/2 subarachnoid hemorrhage impeding arachnoid granulation resorption or meningitis Or NPH
239
what differentiates intra axial from extra axial pachymeninges vs leptomeninges
pia membrane pia and arachnoid are lepto, dura is pachy
240
what do T1 and T2 represent on MRI
T1: longitudinal relaxation T1 short=bright, T1 long=dark T2: transverse relaxation T2 short=dark, T2 long=bright
241
What substances are T1 short? T2 short/long
T1 short: blood, fat, melanin, protein/minerals T2 short: blood, calc, vascular flow void, cellular tumor T2 long: water/edema, mucin
242
what brain lesions restrict diffusion
stroke, abscess, lymphoma, epidermoid, herpes encephalitis, choroid plexus cyst/xanthogranuloma
243
MRI spectroscopy peaks
choline 3.2 creatinine 3.0 NAA 2.0
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normal enhancement in brain
no blood brain barrier choroid plexus, pituitary and pineal glands,
245
periventricular subependymal enhancement can be seen with
ventriculitis (CMV) lymphoma (hyperattenuating on CT, T2 dark, diffusion restriction) glial tumor
246
what can demonstrate gyriform enhancement nodular enhancement?
-herpes encephalitis, meningitis -hematogenous mets at gray white junction
247
what can demonstrate ring enhancement (neuro)
-abscess (diffusion restriction) -demyelinating disease (incomplete C ring) -glioma (surrounding infiltrative tumor does not enhance) -lymphoma in immunocompromised (basal ganglia) -subacute contusion -mets -radiation necrosis
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what can pachymeningeal enhancement represent
dural enhancement: -intracranial hypotension (sagging tonsils and enlarged pituitary) -meningioma -granulomatous disease
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what can leptomeningeal enhancement represent
pial and arachnoid enhancement: -bacterial/fungal meningitis -viral encephalitis -carcinomatosis (GBM, ependymoma, medulloblastoma, lymphoma) -slow vascular flow is a mimic -moya moya ivy sign
250
brain tumors are typically what on MRI what are exceptions
typically T1 dark and T2 bright T1 bright: melanoma, hemorrhagic mets, teratoma/dermoid T2 dark: hypercellular lymphoma, medulloblastoma, germinoma
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cowden syndrome associated with
breast hamartoma (breast within a breast) lhermitte duclos (corduroy or tiger striped cerebellar gangliocytoma)
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differential for CNS cystic mass with enhancing nodule
-hemangioblastoma (VHL) -juvenile pilocytic astrocytoma (kids, posterior fossa, NF1) -pleomorphic xanthoastrocytoma (temporal lobe) -ganglioganglioma (young adult, refractory temporal lobe epilepsy)
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differential for crossing midline/corpus callosum lesion
-glioblastoma multiforme (infiltrative surrounding T2 tumor) -lymphoma (avid homogeneous enhancement) -demyelinating disease
254
gliomatosis cerebri looks like
T2 signal affecting multiple lobes no enhancement infiltrative astrocytoma
255
What is an oligodendroglioma and associations?
A slow growing cortical based mass with CALCS primarily young to middle-aged individuals and associated with seizures.
256
what do intramedullary spinal cord tumors look like and what kinds?
cause expansion and enhancement of the cord Ependymoma (adult): well defined w syrinx and hemorrhage Astrocytoma (kid): more eccentric and irregular Hemangioblastoma: wide cord with edema demyelinating lesion
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What types of conditions can cause cord enhancement?
Ependymoma, astrocytoma, viral myelitis (cord and cauda equina enhancement compared to cauda enhancement in Guillain Barre)
258
intraventricular lesions include
-neurocytoma (young adult): bubbly appearance (Swiss cheese) attached to septum pellucidum with cystic areas, calcs, necrosis -choroid plexus papilloma (4th vent adults, lateral vent children): avid enhancement -meningioma: atrium -SEGA: foramen of monro; TS; homogenous enhancement -subependymoma: don’t enhance
259
meningioma features and nuc activity
enhancing diffusion restriction osseous hyperostosis calcs NF2 Take up octreotide and T99m MDP
260
what lesions can be seen in the cerebellopontine angle
-epidermoid cyst: diffusion restrict, csf signal but does not suppress on flair, cauliflower like borders -vestibular schwannoma: avid enhancement, expands porus acousticus like ice cream cone -meningioma: enhance and diffusion restrict -aneurysm: vertebrobasilar flow voids
261
pseudotumor cerebri
idiopathic intracranial hypertension -overweight black female -flattening of sclera, optic disc protrusion, nerve sheath tortuosity/edema -empty sella, enlarged meckels cave -slit like ventricles -can compress CN6
262
pituitary lesions and features
-craniopharyngioma (kids): cystic mass w calcs -rathke cleft cyst (adults): claw sign -pituitary adenoma: T1 dark, slow enhancement -pituitary apoplexy: T1 bright -lymphocytic hypophysitis: IgG4
263
what does pineal gland secrete What can happen if the mass of the pineal gland compresses the tectal plate?
Melatonin Parinaud syndrome * Upward gaze paralysis * Nystagmus * Pupillary light disassociation
264
pineal gland tumors can cause what? and how to distinguish?
parinaud syndrome: vertical gaze palsy Germinoma: Central calcification 'engulfed' Pineoblastoma: exploded calcifications, invades adjacent structures, diffusion restriction
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What is the relationship between bilateral retinoblastomas, trilateral, and quadrilateral retinoblastomas?
-unilateral is spontaneous (leucokoria white pupil reflex) -bilateral is familial -pineoblastoma with bilateral retinoblastomas=trilateral retinoblastoma -pineoblastoma with bilateral retinoblastomas and sella involvement=quadrilateral retinoblastomas
266
What is the association of quadrigeminal plate lipoma?
Associated with agenesis or hyperplasia of corpus callosum
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What may affect all of Waldeyer lymphatic ring (and what does it involve)?
Non Hodgkin lymphoma The Waldeyer lymphatic ring includes the lingual, palatine, and adenoidal lymphatic tissues.
268
subarachnoid hemorrhage locations:
typically due to aneurysm rupture in non trauma cases -ACA: interhemispheric fissure -MCA: sylvian fissure -PCOM: basal cistern -basilar tip: interpeduncular cistern
269
subarachnoid hemorrhage grading and complications
hunt and hess score for mortality -vasospasm 7 days post (Fisher scale for severity) -acute hydrocephalus (communicating extraventricular) -superficial siderosis: iron overload-> sensorineural deafness and ataxia
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What can cause nontraumatic nonaneurysmal SAH?
Prolonged but reversible cerebral vasoconstriction syndrome Or perimesencephalic SAH
271
What causes an epidural hematoma? What is the primary cause of a subdural hematoma?
-Fracture of squamous temporal bone and tearing of MMA -Tearing of cerebral veins
272
What leads to intraventricular hemorrhage and what complication?
Tearing of subependymal veins May result in ependymal scarring which obstructs the cerebral aqueduct-> obstructive hydrocephalus
273
What is associated with parenchymal hemorrhage in younger individuals?
AVM Enlarged artery feeding the hemorrhage and adjacent encephalomalacia Spetzelr martin scale evaluate surgical risk for AVM resection
274
Where can dural arteriovenous fistulas (DAVF) be located?
Posterior fossa or adjacent to cavernous sinus enlarged meningeal artery or cortical vein
275
What features and apperance are associated with cavernous malformation?
popcorn calc, dark hemosiderin rim Associated with developmental venous anomaly (DVA): caput medusae It is typically low flow and angiographically occult.
276
What type of hemorrhage is commonly seen in young females
bilateral thalamus hemorrhage in venous thrombosis
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What are the types of intracranial hemorrhagic neoplasms?
Glioblastoma and vascular metastases (melanoma, RCC, thyroid, breast, lung)
278
What characterizes the Chiari malformations?
1) Downward displacement of tonsils +/- syrinx 2) Downward displacement of tonsils and cerebellum, low lying torcula, tectal beaking, towering cerebellum, hydrocephalus, +/- lumbar myelomeningocele 3) low occipital/high cervical encephalocele, may be associated with tethered cord, agenesis of corpus callosum
279
What do Le Fort fractures involve and what are the types?
Pterygoid plates 1) Floating palate: Horizontal through all maxillary walls 2) Pyramidal fracture: Central midface, nose, and hard palate move together; orbit and maxilla are involved 3) Complete midface dissociation: fractures through orbits and zygomatic arches
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segments of the ICA
1) cervical 2) petrous 3) lacerum 4) cavernous 5) clinoid 6) supraclinoid (ophthalmic at the dural ring) 7) communicating (PCOM and anterior choroidal artery) MCA and ACA
281
circle of willis
282
What does the recurrent artery of Heubner supply and where does it originate?
The recurrent artery of Heubner supplies the caudate head and anterior limb of the internal capsule. A1 artery
283
What supplies the caudate and lentiform nucleus?
Medial lenticulostriate perforators from A1 Lateral lenticulostriate perforators from MCA (including putamen, external capsule, posterior limb)
284
What does the Pcomm travel alongside?
3rd cranial nerve A Pcomm aneurysm can lead to CN3 palsy.
285
What type of infarction is associated with a V shaped bilateral ventromedial thalamic infarction?
Artery of Percheron infarction ## Footnote This variant features a single dominant thalamic perforator from the PCA.
286
What structures does the anterior choroidal artery supply?
Optic chiasm, hippocampus, posterior limb of internal capsule
287
Fill in the blank: Chronic infarct is associated with _______.
Wallerian degeneration (Atrophy of ipsilateral cerebral peduncle and ventral pons) and cortical laminar necrosis
288
What vascular anomaly can cause high output cardiac failure in childhood?
Vein of galen malformation (AV fistula from thalamoperforator branch into deep venous system, with enlarged median prosencephalic vein) Hepatic hemangioendothelioma and sacrococcygeal teratoma
289
What can be seen in cases of cavernous carotid fistula?
enlarged/engorged superior ophthalmic vein Proptosis and CN palsy
290
What is capillary telangiectasia and describe its appearance?
A condition characterized by dilated capillaries Brush stroke like enhancing lesion in brainstem or pons, no mass effect ## Footnote It is typically low flow and angiographically occult.
291
intracranial anuerysms causes and locations
Saccular aneurysm: hypertension at branch points, anterior Fusiform aneurysm: atherosclerosis or chronic dissection at vertebrobasilar system Mycotic aneurysm: from septic emboli, typically distal arterial beyond circle of Willis Oncotic aneurysm: neoplasm, embolus from left atrial neoplasm
292
deep intracranial veins
293
What is the venous angle?
Intersection of septal vein and thalamostriate veins to form the internal cerebral veins angiographic landmark for foramen of Monro
294
What does the vein of Trolard connect? What does the vein of Labbe connect?
Superficial cortical veins to superior sagittal sinus Temporal lobe veins to transverse or sigmoid sinus
295
What is the empty delta sign?
Filling defect in superior sagittal sinus from venous thrombosis
296
What conditions can lead to venous thrombosis? What are potential complications
* Pregnancy * Oral contraceptives * Malignancy can lead to venous hypertension and infarct or hemorrhage.
297
venous thrombosis results in infarct where: -Superior sagittal sinus thrombosis -Deep venous thrombosis -Transverse sinus thrombosis
-> infarct of parasagittal high convex cortex -> infarct of bilateral thalami -> infarct of posterior temporal lobe
298
cervical lymph nodes
1A/1B separated by digastric 2A/2B separated by IJV 2/3 separated by inferior hyoid 3/4 separated by inferior cricoid
299
What is the most common childhood soft tissue sarcoma in the head and neck?
Rhabdomyosarcoma affects orbit>sinus>ear>neck
300
What are the variants of Multiple Sclerosis (MS)?
* Concentric balo sclerosis: alternating concentric bands of normal and abnormal myelin (onion) * Marburg: fulminant form of MS leading to death in months * Devic disease (neuromyelitis optica): optic nerves and spinal cord transverse myelitis with antibodies to aquaporin 4
301
What demyelinating disease affects the corpus callosum in male alcoholics?
Marchiafava-bignami
302
T2 bright medial thalamus and periaqueductal gray matter mammillary body enhancement
Wernicke encephalopathy: * Ataxia * Confusion * Oculomotor dysfunction
303
What is the imaging finding in PRES?
Symmetric posterior subcortical white matter T2 hyperintensity ## Footnote Often associated with conditions like hypertension, eclampsia, and sepsis.
304
symmetric anterior subcortical white matter T2 hyperintensity, specifically in the anterior temporal lobe or paramedian frontal lobe
CADASIL (cerebral autosomal dominant arteriopathy w subcortical infarcts and leukoencephalopathy) characterized by recurrent stroke and migraine in younger pt
305
What does progressive multifocal leukoencephalopathy (PML) involve vs HIV encephalitis
Asymmetric T2 signal of bilateral white matter, involving arcuate subcortical U fibers in PML HIV is symmetric and spares the subcortical U fibers
306
What causes subacute sclerosing panencephalitis (SSPE) and how does it appear?
Reactivation of measles periventricular white matter lesions with surrounding edema.
307
What is acute disseminated encephalomyelitis (ADEM) associated with? What does it involve/spare?
Post viral infection or vaccination in children Ring enhancing T2 bright lesions WITHOUT involvement of callososeptal interface
308
What is the primary feature of Cryptococcus infection in the brain?
Basilar meningitis and leptomeningeal enhancement gelatinous pseudocysts along basal ganglia spaces dilated perivascular spaces
309
What is the cause of Neurocysticercosis and appearance?
Taenia solium parasite with cysts, ring enhancing lesions, or parenchymal calcs causing seizures
310
What imaging finding is associated with Toxoplasmosis in the brain?
Ring enhancing lesions and calcifications in basal ganglia; no diffusion restriction or FDG uptake Hydrocephalus
311
What are the imaging characteristics in Herpes encephalitis?
Mesial temporal lobe, insular cortex T2 signal; gyral enhancement
312
What are the imaging characteristics of HIV encephalopathy?
Symmetric T2 signal in periventricular and deep white matter; cerebral atrophy
313
What imaging findings are associated with CMV encephalitis?
Ventriculitis with subependymal flair hyperintensity and enhancement
314
What is a characteristic imaging finding in Creutzfeldt Jakob disease?
Cortical ribboning and basal ganglia/thalami flair and restricted diffusion caused by prions and associated with DWI and FLAIR pulvinar sign and hockey stick sign of dorsomedial thalamus
315
What neuro imaging characteristic is associated with liver disease?
T1 hyperintense in globus pallidus and substantia nigra due to manganese deposition
316
What MRI findings are indicative of hypoglycemia?
Bilateral T2 hyperintense in cortex gray matter, hippocampi, and basal ganglia
317
What are the MRI characteristics for HIE and how to distinguish from hypoglycemia?
Hypoxic-Ischemic Encephalopathy T2 hyperintense cortex gray matter, hippocampi, and basal ganglia white cerebellum sign distinguishes from hypoglycemia: sparing the cerebellum
318
What are the MRI findings associated with carbon monoxide exposure?
Symmetric T2 hyperintense and restricted diffusion in globus pallidus with symmetric confluent cerebral white matter involvement
319
What does methanol poisoning look like?
hemorrhagic necrosis of putamen (T1 bright CT dense) optic neuritis/nerve atrophy white matter edema
320
What is the order of neck fascia?
retropharyngeal space->alar fascia->danger space->prevertebral fascia->prevertebral space
321
What is Ludwig angina?
Infection of the floor of the mouth
322
What is Lemierre syndrome?
Septic thrombophlebitis of tonsillar and peritonsillar veins with spread to the internal jugular vein and septic emboli Recent infection or ent surgery Fusobacterium necrophorum
323
What is a Bezold abscess?
Complication of otomastoiditis; opacification of middle ear and mastoid air cells with erosion
324
What is a ranula?
A mucous retention cyst from the sublingual gland
325
What is a dermoid cyst?
A midline floor of mouth fluid lesion with the appearance of a sack of marbles (fat globules)
326
What is a thyroglossal duct cyst?
A midline cyst, typically infrahyoid From base of cecum to thyroid
327
If a cystic lesion is seen near the angle of the mandible in a child, what is the most likely diagnosis? in an adult, what is the most likely diagnosis?
Branchial cleft cyst Cystic papillary thyroid metastasis or squamous cell carcinoma metastasis
328
What is a Thornwaldt cyst?
A cyst located in the midline of the nasopharynx
329
What is vocal cord paralysis characterized by vs laryngocele?
Medialized aryepiglottic fold and enlargement of pyriform sinus Dilation of laryngeal ventricle
330
What is the agger nasi cell and concha bullosa?
Most anterior ethmoid air cell, can obstruct frontal recess Pneumatization of middle turbinate
331
What is Potts puffy tumor?
Complication of sinusitis resulting in osteomyelitis of the frontal bone with subgaleal abscess and soft tissue edema
332
What is the difference between chronic allergic fungal sinusitis and acute invasive fungal sinusitis
Chronic allergic: central curvilinear/serpiginous hyperdense material; deossified walls Acute invasive: no hyperdensity; aggressive with local invasion, bony destruction, intracranial/orbital spread
333
What is an antrochoanal polyp vs inverting papilloma?
Extend from maxillary sinus into nasal cavity with widening of ostium; NO erosion of bone Papillomas demonstrate cerebriform pattern of enhancement; remodel bone WITH erosion
334
What is a mucocele?
Expanded sinus with thinned walls and osseous erosion due to obstruction of ostia; Most common frontal sinus
335
What do the middle, superior and inferior meatus drain
Superior: Posterior ethmoids and sphenoids Middle: Anterior ethmoids, frontal and maxillary sinuses drain from middle meatus via hiatus semilunaris and ostiomeatal unit Inferior: Lacrimal duct
336
parotid gland normally contains
contain facial nerve lymphoid tissue
337
parotid gland tumors
benign: -pleomorphic adenoma (enhances, T2 bright) -warthins tumor (does not enhance, T2 bright) malignant: -mucoepidermoid carcinoma (enhances) -adenoid cystic carcinoma (enhances): perineural invasion -lymphoma
338
What is a characteristic symptom of sarcoidosis vs Sjogren's syndrome?
Sarcoid: Bilateral painless parotid swelling Sjogren's syndrome: primarily affects salivary and lacrimal glands (dry mouth and dry eyes)
339
What are the symptoms of uveoparotid fever?
Uveitis, parotid enlargement, facial nerve palsy
340
pterygopalatine fossa pterygomaxillary fissure, sphenopalatine fossa, inferior orbital fissure, pterygopalatine canal to oral cavity
341
sublingual and submandibular glands
342
What is juvenile nasopharyngeal angiofibroma?
benign vascular tumor with nasal obstruction and epistaxis avid enhancement mass expands the pterygopalatine fossa and causes anterior bowing/displacement of the posterior maxillary sinus wall skull base erosion
343
What is the most common malignant neoplasm of the anterior skull base in children and adults?
Rhabdomyosarcoma in children Squamous cell carcinoma in adults, often presenting with bony destruction and intensely enhancing maxillary antrum.
344
What is the most common malignant neoplasm of the anterior skull base in adults?
Squamous cell carcinoma
345
What are the CT characteristics of Esthesioneuroblastoma (olfactory neuroblastoma)?
Slight hyperattenuating mass; Intermediate on T1 and T2; Peripheral tumor cysts at the margins of the intracranial portion of the mass Bimodal age distribution in teenagers and middle age
346
What is the key characteristic and signal appearance of Adenoid cystic carcinoma on MRI? Where do they typically arise from?
Perineural spread Water signal with enhancement T1 and T2 Minor salivary glands
347
Retropharyngeal abscess most commonly from
suppurative pharyngitis
348
Middle ear consists of what
tympanic membrane ossicles (malleus, incus, stapes) stapedius facial nerve oval window between air filled middle and fluid filled inner ear
349
What is EAC atresia?
Abnormal malleus and incus
350
What is EAC exostosis characterized as and commonly known as?
characterized by bony outgrowths in the external auditory canal, often associated with frequent exposure to cold water Surfers ear
351
What condition is referred to as swimmers ear?
External otitis inflammatory condition of the external ear canal, frequently caused by water exposure and infections.
352
What is necrotizing external otitis?
Malignant otitis externa serious infection typically seen in diabetic or immunocompromised patients, characterized by extensive enhancement and bony erosion.
353
What does keratosis obturans involve?
Keratin plugs bilaterally ## Footnote Keratosis obturans is a condition characterized by the accumulation of keratin in the external auditory canal, leading to blockage.
354
What are the key features of a facial nerve schwannoma?
Enlargement of bony canal, Brisk contrast enhancement, Facial nerve palsy or conductive hearing loss
355
Red vascular mass behind tympanic membrane->
Glomus tympanicum: Extra-adrenal pheo aka paraganglioma Pulsatile tinnitus or conductive hearing loss or hemangioma or aberrant carotid artery
356
Blue mass behind tympanic membrane->
Cholesterol granuloma/cyst: Soft tissue middle ear mass with bony erosion T1 and T2 hyperintense
357
White mass behind tympanic membrane->
Cholesteatoma (congenital in middle ear, acquired anywhere else): Well circumscribed soft tissue mass with bony erosion, blunting of scutum, and erosion of the ossicles Involvement of lateral semicircular canal, tegmen tympani, and facial nerve Diffusion restriction but no enhancement, T2 bright
358
inner ear components
Labyrinth, utricle, saccule, vestibular and cochlear aqueduct Labyrinth (Contained within otic capsule): -cochlea (2.5 turns) -vestibule (balance) -semicircular canals (percept movement)
359
what is cochlear dysplasia vs michel aplasia
incomplete development of the normal 2.5 turns vs complete lack of inner ear development
360
otosclerosis/otospongiosis
Bone dysplasia of otic capsule replaced by spongy bone classic hearing loss in young and middle aged women Bilateral
361
types of labyrinthitis
Acute: pus with diffuse enhancement of inner ear Fibrous: replacement of endolymph & perilymph with fibrous strands; Decreased fluid signal and enhancement Labyrinthitis ossificans: replacement of endo and peri lymph with calcified debris
362
types of t bone fractures
Longitudinal (most common): Involve ossicles-> conductive hearing loss Transverse (perpendicular to long axis): Involve bony labyrinth-> sensorineural hearing loss; 50% with facial nerve or vascular injury
363
petrous apex lesions
-Cholesterol cyst/granuloma: T1 and T2 bright -Cholesteatoma: T1 dark and T2 bright w diffusion restriction -Apical petrositis (petrous apicitis): Opacification of petrous apex air cells w bony demineralization and enhancement -cephalocele: meckel cave herniation into petrous apex, cystic -LCH: well circumscribed destructive lesion with nonsclerotic margins, and marked enhancement -Schwannoma: intralesional cysts, smooth enhancement, Bony remodeling
364
Gradenigo triad:
otomastoiditis, facial pain (meckels cave trigeminal neuropathy) and lateral rectus palsy (dorellos canal CN6 palsy)
365
midline clivus or petrous apex lesions
Chondrosarcoma: -Ring and arc chondroid matrix on CT -Lobular, cauliflower mass, T2 bright, off midline Chordoma: -T2 bright w bony destruction and enhancement -Arises from midline axial skeleton
366
paraganglioma appearance
salt and pepper appearance highly vascular and enhance avidly associated with MEN 1 and NF1 Octreotide positive
367
paraganglioma types
-glomus jugulare: pulsatile tinnitus and hearing loss w moth eaten bony destruction of middle ear floor -glomus tympanicum: pulsatile tinnitus and hearing loss w red retrotympanic mass (middle ear preserved) -glomus caroticum: SPLAYS ICA and ECA -glomus vagale: displaces ICA and ECA anteriorly
368
What does the cavernous sinus connect with via the superior orbital fissure?
CN3 oculomotor, CN4 trochlear, CNV1 ophthalmic trigem, CN6 abducens, superior ophthalmic vein ## Footnote CN3 controls superior, medial, inferior rectus and inferior oblique; CN4 controls superior oblique; CNV1 provides sensory innervation to the upper face; CN6 controls lateral rectus.
369
What does the foramen rotundum connect with via the inferior orbital fissure?
CNV2 maxillary trigeminal ## Footnote CNV2 provides sensory innervation to the inferior eyelid, upper lip, and nose.
370
What is a potential sequela of orbital infection?
Cavernous sinus thrombosis
371
What characterizes an orbital cavernous hemangioma in adults?
Typically intraconal with vascular channels and slow moving blood, bony remodeling and patchy enhancement
372
What are the characteristics of capillary hemangioma in pediatric patients?
Skin lesions like strawberry hemangiomas, enlarge over first months then involute
373
How does orbital lymphoma typically present?
Painless downward proptosis, typically involving the lacrimal gland ## Footnote It molds to the globe rather than deforming it and appears T1 and T2 hypointense on imaging.
374
What is the presentation of orbital pseudotumor?
Painful proptosis, affects lacrimal gland and extraocular muscles without sparing myotendinous junction ## Footnote Involves lymphocytes, plasma cells, and macrophages; similar pathologic process to Tolosa Hunt syndrome.
375
What characterizes orbital lymphangioma?
Typically extraconal with multilocular cystic mass and internal fluid levels from hemorrhage
376
Where do orbital schwannomas/neurofibromas typically occur?
Superior orbit due to CNV1 nerve involvement ## Footnote Appears T1 hypointense and T2 hyperintense with enhancement.
377
What types of cancer commonly metastasize to the orbit?
* Breast * Lung * Thyroid * Renal cell carcinoma (RCC) * Melanoma
378
What is metastatic ophthalmopathy characterized by?
Fibrosis of extraocular muscles, typically bilateral ## Footnote It prevents exophthalmos due to the fibrosis.
379
What is optic nerve glioma associated with in children?
Astrocytoma associated with NF1, typically bilateral
380
What is the typical presentation of meningioma affecting the optic nerve?
Circumferential thickening of nerve sheath with uniform enhancement, tram track sign with nonenhancing nerve (donut sign) ## Footnote Most commonly seen in middle-aged females.
381
What is retinopathy of prematurity?
Prolonged oxygen therapy affecting premature infants ## Footnote It can lead to hemorrhage, retinal detachment, and microphthalmia with increased attenuation due to prior hemorrhage.
382
What is associated with coloboma?
It leads to a cone-shaped or notch-shaped deformity associated with trisomy 13, 18, CHARGE, and VATER.
383
What characterizes Coat disease?
Vascular abnormalities of the retina affecting boys, with lipoproteinaceous subretinal exudates which do not enhance ## Footnote This condition can result in retinal detachment.
384
What defines septo-optic dysplasia?
Optic nerve hypoplasia and agenesis of septum pellucidum ## Footnote It is associated with schizencephaly.
385
what are the layers in the spine
Dura/arachnoid-> subarachnoid-> pia-> cord
386
intradural extramedullary spinal lesions
Schwannoma/neurofibroma: involve neuroforamina myxopapillary ependymoma: only conus or filum Meningioma Drop Mets: zuckerguss epidermoid cyst: CSF signal but doesn't suppress, restricts diffusion
387
where is chordoma typically located and how does it appear
sacrococcygeal>clivus>spine C2 T2 bright and enhancing Irregular scalloped borders may have internal calcs
388
spinal nerve roots exit where
Cervical: nerve root exits above vert body C1-C7 C8 nerve root exit below C7 vert body Thoracic and lumbar: nerve roots exit below vert body 31 paired nerves
389
modic type changes 1-3
1) edema: T1 dark, T2 bright 2) fat: T1 bright, T2 bright 3) fibrosis/sclerosis: T1 dark, T2 dark
390
What is a synovial cyst vs tarlov cyst?
Synovial cyst is associated with facet arthropathy ## Footnote Synovial cysts often form due to degeneration of facet joints.
391
What does T2 signal along the annulus fibrosis indicate?
a high intensity zone/annular fissure
392
What spinal condition spares discs? what is the associated wedge shaped compression of the anterior vertebral body called
Pott disease/tuberculous osteomyelitis Gibbus deformity
393
What is the predominant blood supply of the distal spinal cord? What is complication of aortic stent graft
Artery of Adamkiewicz Cord infarct: T2 bright cord with diffusion restriction
394
What is diastematomyelia?
Congenitally split spinal cord
395
What is a Dysembryoplastic neuroepithelial tumor (DNET)?
Lobular bubbly intramural mass typically in temporal lobe, Low rCBV
396
What are the features of Osteoarthritis?
Older, Asymmetric joint space narrowing, osteophytes, Sclerosis of subchondral bone and cystic change, DIP>1st CMC> PIP, Inferior portion of SI joint (the only synovial joint)
397
What are the characteristics of Erosive Osteoarthritis?
Elderly females, DIP> 1st CMC> PIP, Swelling and gull wing appearance, Central erosion and marginal osteophytes
398
What are the characteristics of Rheumatoid arthritis?
Periarticular osteopenia Symmetric joint space narrowing, marginal erosions, PIP, MCP, Carpals, ulnar styloid, All three compartments affected in knee, High riding humeral head on shoulder with penciling of clavicle
399
True or False: Osteoarthritis typically presents with symmetric joint space narrowing.
False ## Footnote Osteoarthritis is characterized by asymmetric joint space narrowing.
400
What are Boutonniere deformity and swan neck deformity associated with? what are Heberden and Bouchard nodes associated with? Ulnar subluxation at the MCPs?
(PIP flex & DIP ext) (PIP ext & DIP flex) Rheumatoid arthritis (DIP and PIP) osteoarthritis rheumatoid arthritis
401
Superolateral or medial migration of hip vs Axial migration of hip-> protrusio deformity
osteoarthritis rheumatoid arthritis
402
Periarticular osteopenia and joint subluxations is associated with? Atlantoaxial subluxation in spine is associated with?
rheumatoid arthritis NO periarticular osteopenia in osteoarthritis rheumatoid arthritis
403
What are the seronegative spondyloarthropathies and what are they associated with?
Psoriatic arthritis (asymmetric) Ankylosing spondylitis (symmetric) IBD related (symmetric) Reactive arthritis (asymmetric) HLA B27 positive and inferior sacroiliitis
404
What is a Romanus lesion? What does the shiny corner sign indicate? What are they associated with
Erosion of margin of vertebral body at disc junction Sclerosis of margin of vertebral body at disc junction ankylosing spondylitis
405
Define bamboo spine, Andersson lesion, and dagger sign what are they associated with
Diffuse syndesmophytes with undulating contour Pseudoarthrosis in ankylosed spine Fusion of spinous processes ankylosing spondylitis
406
What are the inflammatory bowel diseases (IBD) associated spondyloarthropathies
* Ulcerative Colitis * Crohn's Disease * Whipple's Disease * Gastric Bypass
407
What are the characteristics of psoriatic arthritis?
* Asymmetric sacroiliitis * Diffuse soft tissue swelling * Sausage digit * Pencil in cup erosions affecting DIPs * Asymmetric but bilateral involvement * Arthritis mutilans variant * Ivory phalanx * Plantar calcaneal spur with periosteal reaction
408
What is the arthritis mutilans variant in psoriatic arthritis?
Telescoping digits/main-en-lorgnette (opera glass hand) deformity
409
What is a characteristic feature of reactive arthritis?
Diarrhea, urethritis, or cervicitis Aggressive marginal erosions, joint space loss, swelling, osteopenia
410
what is acroosteolysis and what can it be seen in
distal resorption of distal phalanx scleroderma: collagen deposition in skin and tissues with periarticular calcifications hajdu cheney: short stature, craniofacial changes Pyknodysostosis: Wormian bones, Osteopetrosis, wide angle mandible
411
what can present with periarticular osteopenia and soft tissue calcifications
dermatomyositis and polymyositis
412
periarticular calcifications can be seen in
dermatomyositis/polymyositis scleroderma HADD CPPD
413
crystal deposition in Supraspinatus tendon, Prevertebral longus coli muscle, Triangular fibrocartilage complex
calcium hydroxyapetite deposition disease (periarticular, globular) x2, calcium pyrophosphate deposition disease (intraarticular)
414
What is Kummel disease?
Gas in vertebral body compression fracture due to osteonecrosis
415
What is gout?
Crystal arthropathy with sodium urate deposition in joints ## Footnote Gout is identified by the presence of negative birefringent crystals, primarily affecting the great toe, and leads to sharply marginated erosions.
416
What are the key features of hemochromatosis?
Bronze diabetes, cirrhosis, CHF, arthropathy Deposition of iron T1 and T2 dark liver and spleen T2 liver is darker than muscle
417
What condition is characterized by enlargement of articular cartilage and widened joint spaces in early disease?
Acromegaly
418
What is shoulder pad sign associated with?
bulky soft tissue nodules and atrophic muscles associated with amyloid arthropathy Infiltration of bones and joints by beta-pleated sheets of amino acids
419
What are the characteristics of hemophilic arthropathy?
Enlarged radial head and widened trochlear notch; Squaring of patella and widened intercondylar notch
420
What can be seen in juvenile idiopathic arthritis (JIA).
Under 16 yo; Abnormal bone length or morphology from epiphyseal overgrowth Atlantoaxial subluxation
421
What is neuropathic arthropathy (Charcot)?
Hypertrophic destruction, dislocation, debris, disorganization
422
What are the features of sarcoidosis?
Polyarthritis with bilateral ankle involvement or with erythema nodosum; Lace-like lytic bone lesions particularly in the middle or distal phalanges.
423
What is an aneurysmal bone cyst (ABC)?
Associated with giant cell tumor; Lytic expansile lesion in posterior elements expansive thin-walled blood-filled cavities with fluid-fluid levels.
424
What does an osteoid lesion look like?
Fluffy cloud like bone
425
What characterizes a chondroid lesion?
Ring and arc or popcorn-like appearance enchondroma, osteochondroma, chondroblastoma, chondrosarcoma
426
What is fibrous dysplasia?
Ground glass matrix appearance with blurring of the trabeculae
427
The fallen fragment sign refers to a
unicameral bone cyst with pathologic fracture.
428
What osseous lesions are typically concentric vs eccentric?
Simple bone cyst, enchondroma, fibrous dysplasia
429
What is enostosis?
Bone island, arise from medulla, normal on bone scan
430
What is osteopoikilosis?
Multiple bone islands and keloid ## Footnote autosomal dominant
431
What is an osteoma?
Slow-growing lesion from cortex of skull frontal/ethmoid
432
What is Gardner syndrome?
Multiple osteomas, intestinal polyposis and soft-tissue desmoid tumors ## Footnote autosomal dominant condition
433
What characterizes melorheostosis?
Proliferation of thickened and irregular cortex with candle-wax appearance
434
What is an osteoid osteoma?
Nidus of tissue surrounded by reactive bone sclerosis; Night pain relieved by aspirin typically in the diaphyses of long bones
435
What defines an osteoblastoma?
Same as OO but greater than 2 cm can be associated with painful scoliosis Not relieved by aspirin
436
What is osteosarcoma?
Malignant with osteoid matrix Bony destruction, periosteal reaction, soft tissue mass primary or secondary, often arising from conditions like Paget disease or following radiation.
437
Wunderlich syndrome
Spontaneous perinephric hemorrhage in the absence of trauma
438
What defines telangiectatic osteosarcoma bone lesions?
Vascular with large cystic spaces filled with blood, may mimic ABC but with solid nodular components
439
Where do parosteal lesions arise from?
Juxtacortical arising from outer periosteum cauliflower-like exophytic morphology.
440
What is a key feature of periosteal lesions?
Juxtacortical arising from inner periosteum, chondroid differentiation, may metastasize to lungs which calcify
441
What is the appearance and characteristic MRI signal of an enchondroma?
Serpiginous in femoral long bone or geographic lytic lesion in the hand Characteristic lobulated hyperintense T2 signal helps differentiate enchondroma from infarct on MRI
442
What is Ollier disease associated with? What characterizes Maffucci syndrome?
Multiple enchondromas Multiple enchondromas and venous malformations producing phleboliths
443
What is an osteochondroma? familial osteochondromatosis
(arises from the metaphysis and grows away from the epiphysis) often pedunculated with cartilagenous cap <2 cm is autosomal dominant
444
what lesion is seen eccentric and crossing the physis of skeletally immature patients
chondroblastoma
445
What is a key feature of chondrosarcoma?
Exophytic, expansile lesion continuous with intramedullary cavity thickening and endosteal scalloping of the cortex with a soft tissue mass
446
What is a Non ossifying fibroma/fibroxanthoma/fibrous cortical defect?
Radiolucent lesion with faint sclerotic rim and cortical thinning
447
What characterizes Fibrous dysplasia?
Replacement of bone with fibrous tissue metadiaphyseal and central multiseptated lucent lesion, can be cystic or ground glass
448
What are the components of McCune Albright syndrome?
Fibrous dysplasia, precocious puberty, cafe au lait spots
449
What defines Mazabraud syndrome?
Fibrous dysplasia and intramuscular myxomas
450
What features are associated with Eosinophilic granuloma?
AKA LCH Lytic lesion with beveled edge in skull floating tooth from alveolar bone resorption in mandible vertebra plana complete collapse in spine destructive lucent aggressive lesion, often lamellated in long bones primarily affects young children 5-10 years old
451
What is Ewing sarcoma?
Aggressive with permeative bone destruction, periosteal reaction, soft tissue mass
452
What are the characteristics, demographic, and nuclear activity of Multiple myeloma/plasmacytoma?
Multiple lytic, diffuse myelomatosis with endosteal scalloping negative on bone scan most common primary bone tumor over 40
453
osseous lesion with fluid fluid levels on MRI
ABC, SBC, GCT, telangiectatic osteosarcoma
454
Tibia diaphysis w soap bubble appearance
Adamantinoma well-circumscribed, expansile and multiloculated with a thin sclerotic rim
455
What is vertebral osteomyelitis/discitis primarily caused by in adults?
Hematogenous arterial spread, spinal surgery, or GU infection spread through the epidural venous Batson plexus
456
What is the Wimberger ring sign associated with? What type of fracture is a Pelkins fracture?
Increased epiphyseal sclerosis Metaphyseal corner fracture with a dense metaphyseal line due to scurvy (Vitamin C deficiency)
457
What are some skeletal changes associated with acromegaly?
* Frontal sinus enlargement * Cranial bone thickening * Enlarged jaw * Beak-like osteophytes of metacarpal heads * Spade-like growths of distal phalanges
458
What are the skeletal manifestations of hyperparathyroidism?
* Subperiosteal resorption * Scalloping with bony denimineralization of 2nd and 3rd middle phalanges * Brown tumors * Salt and pepper appearance of skull
459
What is renal osteodystrophy characterized by?
Osteomalacia and secondary hyperparathyroidism due to hypocalcemia in renal failure presents with a rugger jersey spine.
460
deposition of calcium in subcutaneous tissue and basal ganglia?
Hypoparathyroidism from parathyroid resection
461
What is pseudohypoparathyroidism and what does it present with?
Defect of PTH receptor It presents with obesity, round facies, short stature, and brachydactyly.
462
What is Paget's disease?
* Osteolytic, Mixed, Sclerotic phase cotton wool skull picture frame vertebral body Thickening of iliopectineal and ilioischial lines w acetabular protrusio Blade of grass or flame shaped margin in long bone
463
What is the Erlenmeyer flask deformity associated with?
Gaucher disease (autosomal recessive disorder involving glucocerebrosidase macrophages) thalassemia (can be alpha or beta type and is also an autosomal recessive disorder)
464
What is sickle cell disease in the skeletal system?
Dactylitis/hand-foot syndrome soft tissue swelling and periosteal reaction ## Footnote Sickle cell disease is an autosomal recessive condition affecting beta chain hemoglobin.
465
What are the skeletal features of thalassemia?
* Prominent marrow expansion/hyperplasia * Hair-on-end striations in the skull * Rodent-like facies * Erlenmeyer flask deformity
466
What is a Freiberg infarction?
Infarction of the 2nd metatarsal
467
What is the talar beak sign associated with?
Talocalcaneal coalition
468
What is the anteater sign associated with?
Calcaneonavicular coalition
469
H shaped/lincoln log vertebral body and AVN/bone infarct
Sickle cell with splenic auto infarction vs gaucher disease where there is splenomegaly, hepatomegaly, and erlenmeyer flask shaped femurs
470
ankle tendons and order
Ant: Tom Harry Dick Post: Tom Dick And Nervous Harry
471
deltoid and spring ligaments are where
spring: calcaneonavicular deltoid: tibiocalcaneal, tibionavicular, tibiotalar
472
what causes flat foot
posterior tibial tendon tear
473
ankle fracture weber classification maissoneuve fracture
Weber A: distal fib fx with intact syndesmosis Weber B: proximal transyndesmotic fracture w syndesmosis rupture Weber C: high fibular fracture above syndesmosis w total syndesmotic rupture and ankle instability (maissoneuve with medial malleolar space widening)
474
pilon fracture
distal tibia comminuted vertical fx of tibial plafond
475
next step knee dislocation with palpable distal pulses
CTA to rule out popliteal artery injury
476
what is a segond fracture and what is it associated with
avulsion of lateral tibial plateau associated with ACL tear (edema in lateral femoral condyle and posterior lateral tibial plateau)
477
Pelligrini stieda lesion?
Post traumatic calcification medial to medial femoral condyle, may be MCL avulsion injury
478
difference between osgood schlatter and jumper's knee
trauma at patella tendon insertion on tibial tubercle trauma at patella tendon insertion on inferior patella
479
What is pigmented villonodular synovitis? associated with?
Benign hyperplastic proliferation of synovium PD dark and susceptibility artifact from hemosiderin Dark brown effusions from prior hemorrhage
480
MRI imaging of arthroplasties, how to improve
Low field strength, fast spin echo Increased receiver bandwidth and increase number of acquisition (NEX) Decrease voxel size (decrease slice thickness and increase matrix size)
481
chance fracture distraction flexion injury Three column unstable fracture
482
1) transverse process 2) pedicle 3) superior articular surface 4) pars interarticularis 5) lamina 6) inferior articular surface 7) spinous process
483
facet dislocation types and mechanism
bilateral interfacetal dislocation: hyperflexion, disruption of posterior ligament w cord injury unilateral interfacetal dislocation: hyperflexion and rotation
484
jefferson fracture=C1 axial loading
485
avulsion fractures off the hip
486
what is odontoid fracture
C2 dens (hyperflexion)
487
what is hangman's fracture
C2 arches/pedicles (hyperextension/distract) Chin hits dashboard or direct blow to face
488
what is complication of this
teardrop FLEXION fracture with bony retropulsion -> Anterior cord syndrome of pyramidal and anterior spinothalamic tracts (Complete paralysis and loss of pain/temp), Dorsal column intact (touch and vibration) compared to teardrop EXTENSION avulsion fracture
489
what is clay shovelers fracture
spinous process (flexion avulsion fx)
490
anterior shoulder dislocation
Hillsachs fracture (posterolateral humeral head depression) Bankart (anteroinferior rim of glenoid)
491
posterior shoulder dislocation
fixed light bulb sign on internal/external rotation
492
biceps tendon injury with relation to rotator cuff
tendon subluxation or displacement: subscapularis tear tendon tear: supraspinatus tear
493
What is an Essex Lopresti fracture?
Radial head fracture and tearing of interosseous membrane with ulnar dislocation at the DRUJ
494
What characterizes a Monteggia fracture dislocation?
Mid diaphyseal ulnar fracture and radial head dislocation at elbow
495
What is a Galeazzi fracture dislocation?
Radius fracture distal third with ulnar dislocation at DRUJ
496
What defines a Colles fracture?
Distal radius with dorsal angulation from FOOSH
497
Hutchinson/chauffeurs fracture Radial aspect of distal radius fracture extending into radial styloid and radiocarpal joint
498
kienbocks disease?
Avascular necrosis of lunate with negative ulnar variance
499
What is mallet finger?
Extension tendon injury of the distal phalanx
500
What injury is described by the term 'Gamekeeper's thumb'?
Ulnar collateral ligament injury at the base of the first proximal phalanx with avulsion fracture
501
What characterizes Mirizzi syndrome?
Stone in cystic duct with external compression of the common hepatic duct ## Footnote This condition may lead to complications like cysto-choledochal fistula.
502
What should be considered if there is dirty shadowing in the liver?
Pneumobilia (central) or portal venous gas (peripheral)
503
What are the ultrasound features indicative of liver disease?
increased echogenicity= fat steatosis increased heterogeneity and nodular surface= cirrhosis/fibrosis
504
What is the water lily sign associated with?
undulating membrane within cyst Hydatid disease (echinococcal cyst with large liver cyst and peripheral daughter cysts) treated with albendazole or mebendazole.
505
multiple tiny targetoid lesions involving the liver and spleen
Candidiasis, commonly seen in immunocompromised individuals
506
What presents with pain and lesion in the dome of the right lob?
Amebic abscess Entamoeba histolytica
507
What is a cavernous hemangioma characterized by on US?
Echogenicity with posterior acoustic enhancement and no flow on color Doppler ## Footnote It is a benign vascular liver lesion.
508
What does a biliary cystadenoma appear as? what finding is concerning?
A multi-septated cystic mass ## Footnote Mural nodules may suggest potential malignant transformation into cystadenocarcinoma.
509
what is target sign on liver ultrasound?
hypoechoic rim concerning for hepatic metastases
510
Doppler flow in venous clot suggests?
tumor thrombus iso HCC propensity for venous invasion
511
hypoechoic liver lesion in post transplant patient
post transplant lymphoproliferative disorder caused by EBV
512
right congestive heart failure or tricuspid regurgitation on hepatic venous waveform
Accentuated A wave D wave becomes deeper than S wave
513
portal hypertension causes/location flow direction?
Presinusoidal: portal vein thrombosis Sinusoidal: hepatic in origin, like schistosomiasis, cirrhosis Post sinusoidal: hepatic vein or IVC thrombosis (Budd Chiari) toward liver= hepatopetal away from liver= hepatofugal (reversed flow)
514
RCC ultrasound
Isoechoic to renal cortex with hypoechoic rim Propensity for venous invasion
515
reversal of flow in renal artery transplant kidney
renal vein thrombosis
516
Bilateral hypoechoic testicular masses
Congenital adrenal rests: embryonic adrenal tissue
517
epididymal cystic lesion internal echoes
Epididymal cyst: anechoic fluid Spermatocele: internal low level echoes (Cystic dilation of epididymis with spermatozoa, typically in head)
518
lower extremity deep venous system
External iliac vein-> common femoral vein-> deep femoral and femoral vein-> popliteal vein-> anterior tibial, peroneal, and posterior tibial veins
519
What is the effect of outflow stenosis and waveform characteristics?
downstream/distal to the transducer High resistance and high velocity, decreased diastolic flow Normal rapid systolic upstroke
520
What are the ultrasound characteristics of thyroid carcinoma?
Solid hypoechoic with punctate calcs and irregular margins ## Footnote These features can indicate malignancy.
521
What is the effect of inflow stenosis and waveform characteristics?
upstream/proximal to the transducer Low resistance and low velocity, increased diastolic flow tardus et parvus waveform
522
Tc99m sestamibi scan false negatives and positives for parathyroid
-: multigland disease, parathyroid hyperplasia +: thyroid nodule, lymph node
523
How does tamoxifen affect breast and uterus?
Estrogen antagonist at breast and agonist at endometrium ## Footnote Tamoxifen can lead to endometrial hyperplasia, metaplasia, and carcinoma.
524
What is concerning for endometrial cancer in postmenopausal women? Next steps?
Endometrium >8mm or >5mm with bleeding biopsy, MRI for extent, PET for mets
525
What are two complications associated with C-section?
* Bladder flap hematoma (vesicouterine space) * Subfascial hematoma (prevesical space)
526
What are paraovarian and parapelvic cysts?
Separate from but near the ovary/renal pelvis
527
On which day does ovulation typically occur?
Day 14
528
What is a Corpus hemorrhagicum?
physiological bleeding into the follicle called after ovulation This structure eventually becomes the corpus luteum.
529
What causes theca lutein cysts? what is the appearance on US
Elevated hCG These cysts are seen in hyperstimulation syndrome, molar pregnancy, multiple gestations, and infertility patients. multilocular spoke wheel pattern on US
530
What is ovarian hyperstimulation syndrome characterized by?
* Ovary enlargement * Ascites or hydrothorax/pleural effusions ## Footnote This condition is related to VEGF dysregulation due to fertility treatment.
531
What are the main features of polycystic ovarian syndrome?
* Obesity/Insulin resistance * Anovulation * Hirsutism * >12 small follicles * string of pearls
532
What is a dermoid cyst also known as? What is a characteristic feature of a dermoid cyst on imaging?
Mature cystic teratoma Complex ovarian cyst with echogenic Rokitansky nodule, contain hair and teeth on MRI T1 and T2 bright
533
What is the tip of the iceberg sign and dot dash sign related to?
Dermoid cyst Obscuration of deeper contents from high attenuation material dot dash pattern represents keratin fibers
534
What is Struma ovarii?
a rare form of mature teratoma containing thyroid tissue in an ovarian teratoma
535
What triad characterizes Meigs syndrome?
* Fibroma (T1 and T2 dark, hypoechoic) * Ascites * Pleural effusion
536
when should gestational sac, yolk sac, and embryo be seen by?
GS: by 5 weeks, hcg >1500 YS: by GS MSD >8 mm Embryo: by 6 weeks, GS MSD >16 mm
537
What is a single umbilical artery associated with?
Trisomy 13 and 18
538
What does placental thickening indicate?
Fluid overload state of fetal hydrops It can manifest as ascites, pericardial effusion, skin thickening, polyhydramnios, and placental enlargement.
539
What is vasa previa? placenta previa?
umbilical cord vessels run accross cervix to placenta placenta covers the cervix, should be >3 cm from the os
540
What is placental abruption?
Premature separation of placenta from uterus can result in subchorionic hematoma (hypoechoic crescent around gestational sac)
541
What characterizes placenta creta?
Deep attachment of placenta into myometrium Moth eaten/swiss cheese placenta with vascular channels Scarring from c-section, D&C, endometritis, adenomyosis
542
What are the types of placental attachment?
* Accreta: attaches to myometrium but no invasion * Increta: placenta invades myometrium * Percreta: placenta penetrates through myometrium and into serosa
543
What does fetal pleural effusion typically indicate if isolated?
Congenital chylothorax iso thoracic duct or lymphatic malformation.
544
What can cause oligohydramnios and it result in?
from renal agenesis, bladder outlet obstruction, ureteropelvic junction obstruction, or ARPKD. Results in Intrauterine growth restriction (IUGR) Potter syndrome (facial dysmorphism, pulmonary hypoplasia, club feet, and musculoskeletal contractures)
545
What are potential causes of polyhydramnios?
* Idiopathic * Diabetes * GI obstruction/atresia
546
What is anencephaly, what is it associated with?
Lack of development of cerebral cortex and calvarium above orbits, absent defect at top of head associated with elevated AFP 2/2 neural tissue exposure to amniotic fluid
547
What is cephalocele?
Midline neural tube defect with protrusion of intracranial structures outside of calvarium most commonly involving the occipital skull
548
What is Dandy-Walker malformation? And association
Dilated fourth ventricle Torcular lambdoid inversion Hypoplastic cerebellar vermis agenesis of corpus callosum
549
What is heterotopic pregnancy?
Simultaneous IUP and ectopic in assistive reproduction
550
What are the characteristics of gestational trophoblastic disease/hydatidiform molar?
Hyperemesis, marked hcg elevation, enlarged uterus, snowstorm appearance
551
What defines a complete mole vs partial mole in gestational trophoblastic disease?
No fetal parts, diploid: 46XX or 46XY (fertilization of egg without chromosome) Fetal parts, triploid: 69XXX, 69XXY, or 69XYY (2 separate sperm fertilize egg) Cystic placenta
552
What is a dizygotic and monozygotic twin?
fraternal: Arise from individually fertilized eggs, 2 eggs from different sperm, always diamniotic/dichorionic identical: Arise from single egg fertilized with single sperm, same sex, genetically identical
553
What does chorionic vs amniotic refer to in twin pregnancies?
Chorion is the outermost membrane, contains placenta amnion is innermost membrane containing embryo
554
What characterizes twin-twin transfusion syndrome? What is a stuck twin?
Disproportionate blood flow, donor is small with oligohydramnios, recipient is large with polyhydramnios (results in hydrops/death) Donor with shrink wrapped amnion
555
What are acardiac twins?
Twin reversed arterial perfusion (TRAP), one twin develops without a functioning heart; reversed flow in acardiac twin
556
What do the arteries and veins do in an acardiac twin situation?
Arteries carry poorly oxygenated blood into fetus, vein carries deoxygenated blood out of fetus ## Footnote Normally, umbilical arteries carry deoxygenated blood away from the fetus and umbilical vein carries oxygenated blood into the fetus.
557
What is the occipital frontal diameter (OFD)? What is the biparietal diameter (BPD)?
Middle of frontal skull to middle of occipital skull Outer edge of skull to inner edge of skull at level of thalami and cavum septum pellucidum
558
what do the banana and lemon signs refer to
chiari 2 malformation -flattened cerebellar hemispheres in posterior fossa with bilobed appearance -calvarium w flattening of frontal bones
559
what is Holoprosencephaly and the types
Failure of midline cleavage (back to front) Alobar holoprosencephaly, semi lobar and lobar holoprosencephaly
560
What is agenesis of corpus callosum associated with?
Absence of cavum septum pellucidum teardrop morphology of lateral ventricles with colpocephaly widely separated ventricular frontal horns (steer horn) parallel configuration of lateral ventricles concave medial borders of lateral ventricles midline interhemispheric cyst
561
What is the absence of cavum septum pellucidum without corpus callosum agenesis known as?
Septo Optic dysplasia
562
What causes hydranencephaly?
Absence of the cerebral hemispheres with CSF filling the cranial cavity Cortical destruction due to infarct or infection
563
What is colpocephaly?
dilation of the occipital horns of the lateral ventricles associated with agenesis of the corpus callosum
564
twin type based on timing of split in MONOZYGOTIC twins
Di/di if split 0-4 days Monochorionic/diamniotic if split 4-8 days Mono/mono if split >8 days Conjoined if split >13 days
565
congenital diaphragmatic hernia locations and associations
Bochdalek hernia of left posterior thorax Morgagni hernia on anterior right Associated with gut malformation and pulmonary hypoplasia
566
enlarged bilateral echogenic kidneys
HIV nephropathy in adult ARPKD in kid (cysts are too small to resolve)
567
What is meconium ileus?
Impacted meconium in the ileum with bowel obstruction, related to cystic fibrosis
568
What is a duplicated collecting system?
inferior and medial ectopic insertion of the superior pole moeity ureter with intramural ureterocele-> obstruction at UVJ Superior and lateral insertion of the inferior pole moiety ureter-> vesicoureteral reflux Contralateral VUR
569
What are posterior urethral valves?
A membranous flap in the proximal urethra causing bladder outlet obstruction This condition can lead to hydronephrosis, hydroureter, and a dilated bladder.
570
What is the keyhole sign?
Dilation of the proximal urethra
571
How does ARPKD differ from ADPKD?
ARPKD is associated with liver fibrosis (inverse relationship), while ADPKD features cysts in the liver
572
What characterizes osteogenesis imperfecta?
Abnormal type 1 collagen leading to Otosclerosis Lucent skull Fibula>tibia Blue sclera decreased bony mineralization
573
What is thanatophoric dysplasia?
A lethal skeletal dysplasia characterized by telephone receiver femurs Rhizomelia platyspondyly cloverleaf skull Normal bony mineralization
574
What are the main features of trisomy 13?
Holoprosencephaly, midline facial anomalies, encephalocele, congenital heart disease, omphalocele, horseshoe kidney, polycystic kidney, polydactyly
575
What is the strawberry sign associated with?
Trisomy 18 Inward bowing of frontal bones of calvarium with the strawberry tip projecting anteriorly
576
What is Beckwith-Wiedemann syndrome?
A condition with increased risk of Wilms tumor and hepatoblastoma characterized by hemihypertrophy, macroglossia, and omphalocele
577
What are the stages of germinal matrix hemorrhage?
1. Confined to matrix 2. Extends into ventricles without ventriculomegaly 3. Extends into ventricles with ventriculomegaly 4. Extends out of ventricles into parenchyma
578
platyspondyly and cloverleaf skull are associated with
Thanatophoric dysplasia -Platyspondyly: flattening of the ossified portion of vertebral bodies -Cloverleaf skull: protrusion of frontal and temporal lobes
579
What is circumferential subendocardial delayed enhancement associated with?
Amyloidosis, systemic sclerosis, cardiac transplant
580
What condition is associated with subendocardial/transmural delayed enhancement?
Ischemic cardiomyopathy
581
What conditions are related to mid myocardial delayed enhancement?
* Dilated cardiomyopathy * Hypertrophic cardiomyopathy * Myocarditis * Sarcoid * Chagas
582
What conditions are associated with epicardial enhancement delayed?
* Viral myocarditis * Sarcoid * Chagas
583
What does left atrium enlargement indicate if the cardiac silhouette is enlarged?
Mitral regurgitation
584
What does left atrium enlargement indicate if the cardiac silhouette is normal?
Mitral stenosis
585
What does aortic enlargement indicate if the cardiac silhouette is enlarged?
Aortic regurgitation
586
What does aortic enlargement indicate if the cardiac silhouette is normal?
Aortic stenosis
587
What is the association of left ventricular aneurysm?
True aneurysm involving all walls with broad neck LAD occlusion
588
What is the association of LV pseudoaneurysm?
False aneurysm with narrow neck, does not involve myocardium Circumflex or RCA occlusion
589
What is right-sided valvular disease associated with?
Tricuspid regurge associated with Carcinoid mets to liver Systemic serotonin degrades valves
590
What characterizes myocardial noncompaction?
Left ventricle heavy trabeculation and thin wall
591
What genetic inheritance pattern is associated with hypertrophic cardiomyopathy?
Autosomal dominant (AD)
592
What can systolic anterior motion of the mitral valve anterior leaflet cause?
* Mitral regurgitation * Left atrial enlargement
593
What heart shape is associated with hypertrophic cardiomyopathy?
Spade shaped heart
594
What method best stratifies risk of sudden death in patients with hypertrophic cardiomyopathy?
Quantitative LGE
595
What are the causes of restrictive cardiomyopathy?
* Idiopathic * Sarcoid * Hemochromatosis * Amyloid
596
What characterizes dilated cardiomyopathy?
Idiopathic concentric enlargement with impaired systole
597
What is the most useful method in quantifying aortic stenosis?
Direct planimetry of aortic valve orifice
598
What is contraindicated for MR examination?
LVAD
599
What does the Oreo cookie sign indicate?
Epicardial fat, effusion, and pericardial fat stripe
600
Where does congenital absence of pericardium typically affect?
Left pericardium near left atrial appendage results in rotation of the heart towards the left
601
What happens when blood pool nulls first?
Myocardium nulls first, due to protein replacement in amyloid
602
What is a thymoma and its associations?
* Invasive * Drop metastases along pleural and pericardial surfaces * Associated with myasthenia gravis * Typically occurs in middle-aged or older patients
603
What are the types of endoleak?
* Type 1: around graft * Type 1a: proximal * Type 1b: distal * Type 2: collateral to excluded aneurysm * Type 3: through graft defect * Type 4: through graft below resolution * Type 5: leak but without definite source
604
What characterizes Takayasu arteritis?
* Long segment stenoses * Younger middle-aged Asian female patients * Involves the aorta and pulmonary artery
605
What characterizes giant cell arteritis (GCA)?
* Long smooth stenoses * Older male patients * temporal artery * armpit area arteries: subclavian, axillary, brachial
606
At what vertebral level is the celiac artery located?
T12
607
At what vertebral level is the SMA located?
T12-L1
608
At what vertebral level are the renal arteries located?
L1-L2
609
At what vertebral level is the IMA located?
L3
610
What is the typical pathway of the right hepatic artery?
Celiac -> common hepatic -> proper hepatic
611
What are the sources of replaced right hepatic artery (RRHA) and accessory right hepatic artery (RHA)?
From SMA
612
What are the supplies of the SMA?
* Distal duodenum * All small bowel * Cecum to transverse colon
613
What arteries are branches of the SMA?
* Inferior pancreaticoduodenal artery * Middle colic artery * Right colic artery * Ileocolic artery
614
What vessels does the IMA supply?
* Left colic artery * Sigmoid arteries * Superior rectal artery
615
What are the branches of the internal iliac artery's posterior division?
* Superior gluteal * Iliolumbar * Lateral sacral
616
What are the branches of the internal iliac artery's anterior division?
* Inferior rectal * Vesicle * Uterine * Obturator * Inferior pudendal * Inferior gluteal
617
What are the branches of the external iliac artery?
* Inferior epigastric * Deep circumflex * Femoral artery
618
What is cystic adventitial disease?
Mucoid adventitial cysts compress popliteal artery ## Footnote This condition involves the formation of cysts in the adventitia of blood vessels, leading to vascular obstruction.
619
What is Paget-Schroetter syndrome?
Compression and thrombosis of subclavian vein in muscular young men ## Footnote This condition is often associated with strenuous upper limb activities.
620
What is subclavian steal syndrome?
Proximal stenosis of subclavian artery results in reversal of vertebral artery flow into the distal subclavian
621
What is a dialysis fistula?
Better long term but must mature before use ## Footnote Dialysis fistulas can have lower flow rates and remain patent. Less intimal hyperplasia
622
What are the characteristics of a dialysis graft?
Worse long term but can be used earlier; require high flow rates to remain patent ## Footnote Dialysis grafts are usually synthetic and can be placed immediately.
623
What is hypothenar hammer syndrome?
Ulnar artery microtrauma at hamate with ischemia of 4-5th digits ## Footnote This syndrome is often seen in individuals who perform repetitive gripping activities.
624
What are the signs of hepatoblastoma?
RUQ calcification, propensity for portal vein and hepatic vein invasion, AFP is elevated ## Footnote Hepatoblastoma is a rare liver cancer in children, often associated with beckwith wiedemann and hemihypertrophy
625
What is Poland syndrome?
Complete or partial unilateral congenital absence of the pectoralis major muscle ## Footnote It is an autosomal recessive condition associated with anomalies of the ipsilateral arm and hand.
626
What does MRI TE stand for?
Echo time ## Footnote It is the interval between radiofrequency pulse application and the collection of the signal.
627
What does MRI TR stand for?
Repetition time ## Footnote It is the interval between sequential radio frequency pulses.
628
What characterizes Swyer-James syndrome?
Hyperlucent unilateral lung, NOT expanded; associated with Mycoplasma ## Footnote This condition results from a previous lung infection leading to airway obstruction.
629
If there is a mirror image right arch, what condition is likely?
Tetralogy of Fallot ## Footnote Patients with truncus arteriosus also likely with mirror image right arch
630
What is D-transposition of the great arteries?
Aorta on right; RV to aorta with PDA; arterial switch procedure ## Footnote This condition results in a parallel circulation instead of a series circulation.
631
What is L-transposition of the great arteries?
Aorta on left; LA to RV to aorta; atrioventricular and ventricular-vessel discordance ## Footnote This condition is also known as congenitally corrected transposition.
632
If there are pericardial metastases, what is the most likely source?
Pulmonary cancer ## Footnote Patients with melanoma also frequently have pericardial metastases
633
What is cardiac angiosarcoma?
involving the right atrium and pericardium; sun ray appearance ## Footnote This aggressive tumor is often associated with radiation exposure.
634
What is myxoma?
Benign cardiac tumor involving the left atrial/interatrial septum; t2 bright myxoid content; enhances compared to thrombus ## Footnote Myxomas are the most common primary cardiac tumors.
635
Where does rhabdomyoma prefer to grow?
Left ventricle; associated with tuberous sclerosis ## Footnote This tumor is the most common primary cardiac tumor in children.
636
Where is cardiac fibroma typically located?
Interatrial septum; dark on T1 and T2 and enhances
637
What is fibroelastoma?
Prefers valves; can cause systemic emboli
638
What is pyriform aperture stenosis associated with?
Central megaincisor holoprosencephaly pituitary dysfunction
639
What does CHARGE stand for?
Coloboma, heart defects, choanal atresia, retarded growth, GU abnormalities, ear anomalies
640
What does VACTERL stand for?
Vertebral defects, anal atresia, cardiac defects, tracheoesophageal fistula, renal anomalies, limb abnormalities
641
What is phlebectasia?
Dilated jugular vein, worse with Valsalva; NOT related to stenosis
642
What is fibromatosis coli?
Torticollis away from lesion two heads of sternocleidomastoid muscle ## Footnote think neuroblastoma if calcifications or lesion is external to SCM
643
What is are the types of gastric volvulus?
Organoaxial: older, greater curvature flips over lesser curvature Mesenteroaxial: kids, antrum flips above GE junction along short axis
644
What is a meconium plug associated with?
intestinal obstruction in newborns NOT associated with cystic fibrosis associated with diabetic mothers and magnesium sulfate for eclampsia
645
What is necrotizing enterocolitis characterized by?
Unchanging bowel pattern and focal bowel dilation in the RLQ; common in cardiac patients, premies, and Hirschsprung disease
646
What is dorsal pancreatic agenesis?
Only central bud, no tail associated with diabetes and polysplenia
647
Hepatic lesion in 0-3 yo
Hemangioma: -Chf and ^EGF Hepatoblastoma: -Associated with Wilms and hemihypertrophy, ^AFP, calcs -Premies and precocious puberty 2/2 bHCG Mesenchymal hamartoma: -Cystic mass with feeding vein 
648
Caroli disease associations
AR Intrahepatic biliary ductal dilitation-> liver fibrosis Polycystic kidney disease and medullary sponge kidney Central dot sign
649
What is hereditary hemorrhagic telangiectasia associated with?
Osler-Weber-Rendu syndrome Multiple AVMs of lung and liver cirrhosis dilated hepatic artery Brain abscess
650
What is a consequence of neonatal renal vein thrombosis?
Acute: renal enlargement Chronic: renal atrophy ## Footnote Related to maternal diabetes
651
What causes neonatal renal artery thrombosis?
Due to umbilical artery catheters ## Footnote It can lead to severe hypertension
652
What are the features of prune belly syndrome?
Pear shaped deficiency of abdominal musculature hydroureteronephrosis and cryptorchidism
653
What types of bladder urachus remnants are there?
Patent urachus, sinus, cyst, and diverticulum ## Footnote These are associated with adenocarcinoma
654
What is nephroblastomatosis?
Nephrogenic rests from birth precursor to Wilms so followed up hypodense rind ## Footnote Typically occurs in children aged 0-3 years
655
What is mesoblastic nephroma?
Hamartoma that involves renal sinus Can be present from birth occurs in children aged 0-3 years
656
What is Wilms tumor typically associated with?
Associated conditions include Beckwith-Wiedemann, Sotos, and WAGR syndrome Around 4 years old Mets to lungs clear cell metastasizes to bone rhabdoid metastasizes to brain
657
What are the characteristics of neuroblastoma?
Calcifications, hypervascular T2 bright encases but does not invade opsoclonus-myoclonus stage 4s has favorable prognosis Younger than Wilms
658
What are the physical features of achondroplasia?
Frontal bossing trident hands narrowing of interpedicular distance tombstone pelvis rhizomelia
659
What is the characteristic thoracic shape in Jeune syndrome?
Bell shaped thorax with short ribs ## Footnote Also known as asphyxiating thoracic dystrophy
660
What are the features of Gorlin syndrome?
Medulloblastoma Multiple odontogenic keratocysts calcifications of the dura/falx basal cell cancer bifid ribs
661
What does 'bone in bone' or 'picture frame vertebra' indicate?
Osteopetrosis
662
What is Klippel-Feil syndrome?
Congenital fusion of cervical spine
663
What is a key characteristic of xenon as a medical imaging agent?
Fat soluble, requires special xenon trap ## Footnote It has a high sensitivity for COPD but a short biological half-life
664
What is Tc99 DTPA used for?
Radiolabeled aerosol that crosses alveolar capillary membrane and is renal filtered ## Footnote Clumping can occur in the mouth, airways, and stomach
665
What is thallium produced in and most sensitive for?
Cyclotron ## Footnote It is most sensitive for CNS lymphoma
666
What is the most common subtype of thyroid cancer? Which subtype has the worst prognosis
Papillary subtype is the most common and does the best with I131 treatment Anaplastic has the worst prognosis, poor response to treatment Medullary has poor response to treatment and is associated with MEN2
667
What is cold on thyroid scans?
Thyroid carcinoma-> Octreoscan/octreotide
668
What can treatment for thyroid cancer lead to?
Pulmonary fibrosis in lung metastases Salivary gland damage in sjogrens
669
When is thyroid cancer considered treatment resistant?
* Medullary subtype * Prior treatment with methimazole * Prior I131
670
What is the dosing for HIDA scan?
0.02 microgram CCK and 0.02 mg morphine
671
What conditions can cause decreased asymmetric renal flow?
* Renal artery or vein thrombosis * Obstruction * Acute rejection or pyelonephritis
672
Normal perfusion and delayed excretion is suggestive of what in the immediate postoperative renal transplant period vs longstanding?
ATN in renal transplant immediately postoperative cyclosporine toxicity in longstanding period
673
In the immediate postoperative renal transplant patient, what does Normal perfusion and delayed excretion suggest? Delayed perfusion and delayed excretion?
ATN Acute rejection
674
What types of fluid collections can occur post renal transplant?
within the first two weeks: * Hematoma * Urinoma (hot on renal scan) late: * Lymphocele with no tracer uptake
675
What conditions are hot on MDP?
* Fibrous dysplasia * Giant cell tumor * Osteoid osteoma * Osteoblastoma * Aneurysmal bone cyst * Meningioma
676
What is the size range of MAA?
10-100 micrometers
677
What is the size range of Y90?
20-40 micrometers
678
What is the size range of sulfur colloid?
0.1-1 micrometers
679
What is the size range of sulfur colloid lymphoscintigraphy?
0.01-0.1 micrometers
680
What are the uses of Sestamibi?
* Parathyroid * Breast * Heart
681
What does lymph node uptake during Sestamibi imaging mean? What affects Sestamibi uptake
cancer background hormone levels
682
What does a false positive in Sestamibi imaging include?
* Fibroadenoma * Fibrocystic change
683
What is a MUGA scan? How is this affected by inclusion of LA or using spleen as background ROI?
Radiolabeled RBCs with cardiac gating for EF false low EF false high EF
684
What is Y90 classified as? Half life? What to assess before Y90 treatment?
Beta emitter 64 hours TcMAA hepatic arterial injection to assess lung shunt Can prophylactically embolize right gastric/gda to prevent ulcers
685
What premedication is used for biliary atresia imaging? What is biliary atresia imaging?
Phenobarbital 5 mg/kg for 5 days 24 hour scan HIDA scan
686
What is the epidemiology of esophageal adenocarcinoma?
White, PPI use, lower esophageal stricture/ulcer chronic reflux leading to Barrett's esophagus
687
What is the epidemiology of esophageal squamous cell carcinoma?
Black, drinking and smoking, alkaloid exposure, mid esophageal stricture
688
Transient fine folds in lower ⅔ that go away with swallowing?
feline esophagus
689
Discrete plaque-like lesions with shaggy irregular luminal surface?
candidiasis
690
What is glycogenic acanthosis?
elevated nodules in asymptomatic elderly patients mimics candidiasis
691
What is the appearance of small ulcers with halo of edema in the esophagus?
herpes
692
What is the appearance Large flat ovoid ulcers in the esophagus?
CMV/HIV
693
What aphthous ulcers are characteristic of?
Crohn's disease
694
Posterior through Killian triangle hypopharynx?
zenker diverticulum
695
Anterolateral below cricopharyngeal muscle in cervical esophagus?
Killian Jamieson pulsion diverticulum
696
What is the location of epiphrenic diverticula?
Pulsion diverticula on the right side
697
What is the difference between pulsion diverticulum and traction diverticulum?
* Pulsion do not empty * Traction will empty mid esophageal triangular related to granulomatous disease
698
What causes esophageal pseudo diverticulosis?
Dilated excretory submucosal glands causing multiple tiny outpouchings related to chronic reflux and strictures
699
What is jejunal diverticulosis associated with?
Bacterial overgrowth and malabsorption
700
What are the characteristics of eosinophilic esophagitis?
Concentric ringed esophagus, young patients, atopy, dysphagia
701
What causes dysphagia lusoria?
Compression from aberrant right subclavian artery
702
What to suspect in dilated esophagus?
* Achalasia * LES does not relax * Absent primary peristalsis * Increased risk of candida similar finidngs in Chagas disease
703
What is pseudoachalasia?
Secondary to cancer at GE junction compared to true achalasia, it never relaxes
704
What is the characteristic of scleroderma related to esophagus and lung?
Incompetent LES with chronic reflux NSIP (ground glass with subpleural sparing)
705
What causes varices in the lower vs upper sophagus?
Portal hypertension leading to uphill varices SVC obstruction leads to downhill varices
706
What is linitis plastica?
contracted desmoplastic deformity of the stomach resembling a leather bottle can be seen in breast and lung cancer met or lymphoma
707
what does melanoma mets of the stomach look like
Multiple button type soft tissue nodules
708
Multiple gastric ulcers = Multiple duodenal ulcers = Multiple marginal ulcers post roux en y =
-chronic aspirin use -zollinger ellison (Duodenal ulcers never malignant and NOT caused by aspirin) -chronic jejunal ischemia
709
What is Menetriers?
Rugal thickening involving fungus, sparing antrum
710
What condition is indicated by isolated gastric varices?
Splenic vein thrombus iso pancreatitis/pancreatic cancer
711
What are the potential complications of Bilroth/Roux en Y surgery?
* Bile reflux gastritis: fold thickening and filling defects in stomach * Increased risk of adenocarcinoma 15 yrs later in gastric remnant * Internal hernia
712
What does small bowel loops separation with tethering indicate?
Carcinoid, typically involves distal ileum
713
What condition is characterized by sand-like nodules in the small bowel?
Whipple or pseudo-whipple (MAC)
714
What is indicated by uniform small nodules in the small bowel?
Lymphoid hyperplasia
715
What does multiple varying size nodules in the small bowel suggest?
Metastasis (melanoma)
716
What does a ribbon-like small bowel appearance indicate?
Graft versus host disease
717
What does the clover leaf sign indicate?
Healed peptic ulcer of duodenal bulb
718
What are the signs of celiac sprue?
* Malabsorption of gluten * Associated iron deficiency anemia * Pulmonary hemosiderosis * Dermatitis herpetiformis * TTG antibody * Cavitary lymph nodes * Splenic atrophy * Increased risk of bowel lymphoma
719
What is gallstone ileus?
Erodes through duodenum and causes distal obstruction at the IC valve w rigler's triad
720
What are the components of Rigler's triad?
* Pneumobilia * Obstruction * Ectopic gallstone location
721
What is the shock complex associated with severe hypotension?
* Thickened bowel loops with diffuse enhancing mucosa * Flat IVC * Delayed nephrograms * Hyperenhancing adrenals * Hypoenhancing liver/spleen
722
Mesenteric mass with starburst appearance and desmoplastic stranding?
carcinoid tumor
723
What type of hernia is a Spigelian hernia?
Along semilunar line (lateral ventral hernia), typically above arcuate line
724
What is a Richter hernia?
Only 1 wall of bowel; no obstruction but risk of strangulation
725
What is an obturator hernia?
Occurs in old ladies with increased intraabdominal pressure; causes paresthesia along inner thigh to knee from obturator nerve compression
726
What is a femoral hernia?
Occurs in old ladies; located below pubic tubercle inferior to inferior epigastric, medial to common femoral vein
727
What defines a direct hernia?
Above pubic tubercle medial and anterior to inferior epigastric artery; defect in Hesselbach’s triangle
728
What characterizes an indirect hernia?
Most common; lateral and superior to inferior epigastric artery; failure of processus vaginalis to close, covered by spermatic fascia
729
What are the symptoms and types of internal hernia?
Paraduodenal is most common Stomach pain after eating, improves with rubbing Lanzert fossa defect (left) Waldeyer fossa defect (right) sac like cluster of dilated small bowel
730
Crohn's disease?
Entire GI tract involvement particularly terminal ileum skip lesions, creeping fat, cobblstoning, string sign fistulas and abscesses
731
What is a significant complication of ulcerative colitis? what is contraindicated?
Toxic megacolon ## Footnote Toxic megacolon carries a risk of perforation (no enema) and is associated with an ahaustral colon.
732
What is ulcerative colitis?
continuous involvement of colon, including the rectum lead pipe sign: Ahaustral colon with granular appearing mucosa associated with colon cancer and primary sclerosing cholangitis
733
What is Behçet's disease characterized by?
* Pulmonary artery aneurysm * Mouth and penis ulcers * Turkish descent
734
What is the ultrasound appearance of an appendix mucocele?
Onion sign
735
What condition is associated with small cysts throughout the colon?
Colitis cystica ## Footnote This condition is often linked with sprue and vitamin deficiencies.
736
What is characteristic of Entamoeba histolytica?
SPARES terminal ileum Bloody diarrhea coned cecum, flask-shaped ulcers liver and spleen abscesses
737
How does colonic tuberculosis typically present?
Involves terminal ileum coned cecum, fleischner sign (inverted umbrella)
738
What is a characteristic imaging feature of C-diff infection?
Accordion sign with contrast trapped inside mucosal folds thumb printing and ulceration
739
What is the significance of large bowel intussusception?
Suspected malignancy, such as adenocarcinoma
740
What is an adenoma (GI)?
can cause mucus diarrhea and severe electrolyte abnormalities Most common benign tumor Villous adenomas have the largest risk for malignancy
741
What is the epiploic foramen of Winslow?
Conduit between Greater and lesser/omental bursa sacs
742
How does the female peritoneum communicate with the extraperitoneal pelvis?
Via fallopian tubes
743
What is the most common location for peritoneal carcinomatosis?
Most common location for peritoneal implants is retrovesical space
744
What is scalloped appearance of the liver and complex ascites?
Pseudomyxoma peritonei Can be seen with mucinous neoplasm from ovary or stomach or appendix mucocele/mucinous cystadenoma perforation
745
What condition is characterized by limited colitis to the cecum?
Neutropenic colitis/typhlitis
746
what is the significance of dual liver blood supply?
compensatory relationship between hepatic artery and portal vein results in peripheral subcapsular transient hepatic attenuation differences (THAD)
747
portal hypertensive colopathy and gastropathy
right colon edema gastric thickening and bleed
748
HCC mechanism
hepatocyte injury-> regenerative nodules (T2 dark)-> dysplastic nodules (bigger, T1 bright/T2 dark)-> HCC
749
HCC imaging characteristics
T2 bright dark on delayed hepatocyte specific Eovist scan (lose function of bile uptake transporter OATP) Exception is well differentiated HCC which retains OATP function and is bright on delayed eovist
750
What must be biopsied in cases of FNH?
Central scar
751
Fibrolamellar HCC typically occurs in? what imaging features
in patients under 35 yo in patients without cirrhosis central scar, calcifications gallium avid
752
Fibrolamellar HCC compred to HCC and FNH?
Normal AFP in fibrolamellar HCC compared to elevated AFP in HCC Scar is dark without enhancement compared to FNH scar with enhancement
753
What is the primary difference between Cholangiocarcinoma and HCC regarding the portal vein?
Encases portal vein vs invades portal vein
754
What is the most common source of liver metastases? what type of neoplasm for calcified liver mets?
Colon mucinous neoplasm
755
Elevated CEA and CA19-9 elevated CA19-9 elevated CEA
cholangiocarcinoma pancreatic cancer colon cancer
756
What does a double target sign on CT indicate?
Pyogenic abscess ## Footnote A single target sign is associated with Klebsiella, while multiple targets are associated with E. coli.
757
What does a bulls eye appearance on liver ultrasound indicate?
Candida
758
What is a potential complication of an amebic abscess in the left lobe?
Can rupture into pericardium ## Footnote This condition requires emergent drainage.
759
What does the tortoise shell liver sign indicate?
Schistosomiasis
760
What does the hot quadrate sign signify?
Focal segment of contrast secondary to SVC obstruction ## Footnote The hot caudate sign is observed in Budd-Chiari syndrome.
761
Enhancement of anterior liver capsule, ascites, peritoneal septations in RUQ?
Fitz Hugh Curtis syndrome ## Footnote This finding is seen in the context of pelvic inflammatory disease.
762
What is the primary and secondary cause of hemochromatosis?
1) Inherited and involves pancreas 2) Acquired related to inflammation/transfusions and involves spleen
763
How do regenerative nodules appear on T1 and T2 in Budd-Chiari syndrome and HCC?
T1 bright in Budd-Chiari and T2 bright in HCC
764
What does the biliary necrosis indicate in a transplant liver?
Hepatic artery thrombosis as the biliary system relies on for blood supply
765
What is the normal resistive index range for the hepatic artery? What is the peak velocity of the hepatic artery typically less than?
0.5-0.7 <200 cm/s
766
What is Aids cholangiopathy similar to?
Primary sclerosing cholangitis but it demonstrates papillary stenosis focal strictures of the extrahepatic ducts greater than intrahepatic.
767
What is recurrent pyogenic cholangitis characterized by?
Dilated ducts full of pigmented stones ## Footnote It is associated with cholangiocarcinoma in the East.
768
What are the main anatomical components of the gallbladder?
* Spiral valves of Heister-> * Neck-> * Body-> * Fundus->
769
Cholelithiasis in kids?
Sickle cell
770
What is a finding in gangrenous cholecystitis? What is emphysematous cholecystitis associated with?
Absent Murphy sign, sloughed membranes/cobwebs on ultasound elderly diabetics with increased risk of perforation
771
What are pancreatic neuroendocrine/Islet cell tumors and what do they demonstrate?
Hypervascular with brisk enhancement -Insulinoma: benign, solitary, small -Gastrinoma: increased gastric acid output and ulcers (Zollinger Ellison syndrome and MEN1)
772
Intrapancreatic spleen imaging features? what study to order
Dark T1, bright T2 tiger stripe mass on arterial restrict diffusion ->Heat treated RBCs and sulfur colloid
773
What is the Whipple procedure?
Pancreatic head, duodenum, gastric antrum, and gallbladder resection
774
What are the complications of the Whipple procedure?
Delayed gastric emptying and pancreatic fistula
775
What condition is characterized by splenomegaly with occasional discrete hypodense nodules?
Spleen Sarcoidosis
776
What are Gamna gandy bodies?
Foci of hemosiderin T2 dark on gradient in the spleen ## Footnote These are siderotic nodules seen in portal hypertension
777
What can cause multiple splenic calcifications?
Sequela of infection, most commonly histoplasmosis
778
What are the causes of a small spleen?
* Sickle cell disease * Radiation * Thorotrast exposure * Ulcerative colitis
779
What conditions are associated with a large spleen?
* Lymphoma * Leukemia * Congestion * Gaucher's disease * Felty's syndrome
780
What is Felty's syndrome?
Splenomegaly, rheumatoid arthritis, neutropenia
781
What distinguishes epidermoid cysts from pseudocysts?
Epidermoid cysts are true cysts with epithelial lining ## Footnote Pseudocysts lack this lining and often arise from inflammation
782
Where are hydatid cysts most commonly found?
* Liver * Lung * Spleen ## Footnote These cysts are caused by Echinococcus infection
783
What is the most common malignant tumor of the spleen?
Splenic lymphoma ## Footnote Characterized by splenomegaly, low density on CT, T1 dark, PET hot
784
What are common sources of splenic metastases?
* Melanoma * Breast cancer * Lung cancer
785
What is unilateral renal agenesis associated with?
* Unicornuate uterus * Mayer-Rokitansky-Küster-Hauser syndrome/mullerian agenesis * Absent epididymis or vas deferens
786
What are the characteristics of renal cell carcinoma (RCC)?
* Calcifications in a fatty, enhancing mass * Mets are hypervascular and lytic * Increased risk in patients on dialysis
787
What does lymphoma/leukemia present as in the kidneys?
Bilateral enlarged kidneys with cortically based nodules or masses
788
What are the categories in the Bosniak cyst classification?
* 1: simple * 2: hyperdense or thin calcs/septa * 3: thick septations/calcs, mural nodules * 4: enhancement
789
If a renal cyst is homogenously >70 HU, what is its likely classification?
Benign proteinaceous/hemorrhagic cyst
790
What characteristics are associated with ADPKD?
Progressive cyst enlargement and loss of function * Liver cysts * Seminal vesicle cysts * Berry aneurysms
791
What are the characteristics of autosomal recessive polycystic kidney disease (ARPKD)?
Smaller cysts initially too small to resolve, increased echogenicity with loss of corticomedullary differentiation ## Footnote Associated with congenital hepatic fibrosis
792
What is Lithium nephropathy characterized by?
Diabetes insipidus and renal insufficiency ## Footnote Often presents with small kidneys and numerous tiny cysts
793
What is the main distinction between pyelonephritis and infarct?
Wedge shaped area of decreased perfusion Infarct spares the cortex (cortical rim sign)
794
What does 'flip flop enhancement' refer to in imaging?
Hypodensity becomes hyperdense on delayed imaging in infarct
795
What defines emphysematous pyelitis?
Gas localized to collecting system
796
What is lobster claw sign in renal imaging?
Necrotic cavity in papillae with linear streaks of contrast in the calyx Ischemic necrosis of renal papillae medullary pyramids in papillary necrosis ## Footnote It is most commonly seen in diabetics and individuals with sickle cell disease.
797
What is the earliest described sign of renal tuberculosis?
Calyceal blunting
798
What is a phantom calyx?
Focal infundibulum stenosis leading to abnormal calyx appearance ## Footnote This is a potential complication of tuberculosis.
799
What is a putty kidney?
Extensive renal calcifications with calcified lymph nodes ## Footnote This is associated with tuberculosis.
800
What are the risk factors for contrast-induced nephropathy?
Renal insufficiency, diabetes, CHF ## Footnote Allergic reactions are not considered risk factors.
801
What is the most common type of nephrolithiasis?
Calcium oxalate
802
Which type of nephrolithiasis is associated with staghorn calculi?
Struvite
803
What type of nephrolithiasis is invisible on X-ray? on CT?
Uric acid Indinavir ## Footnote Uric acid stones can be treated with pH medications to dissolve them.
804
What is cortical nephrocalcinosis?
Sequela of cortical necrosis after drop in BP ## Footnote It presents as a hypodense non-enhancing rim with thin calcifications.
805
What characterizes medullary nephrocalcinosis?
Hyperechoic renal papilla/pyramids ## Footnote This condition is often seen in hyperparathyroidism and medullary sponge kidney, lasix in kids
806
What is the consequence of a Page kidney?
subcapsular hematoma or collection-> Compression leading to hypertension
807
What is a delayed nephrogram vs a persistent nephrogram?
Asymmetric non-enhancement of the kidney bilateral retained/delayed enhancement 2/2 shock or hypotension ## Footnote This can suggest renal ischemia or obstruction.
808
What is a significant indicator of a sick transplant kidney?
Swollen, Increased RI > 0.7 ## Footnote This is a sign of possible complications such as rejection.
809
What is the risk associated with transplant patients?
Significant increase in cancer risk: skin, lymphoma, colon ## Footnote Annual skin checks are recommended for early detection.
810
What is PTLD in the context of transplants?
Mass encasing hilum ## Footnote It is associated with EBV and often requires prophylactic treatment with rituximab.
811
What are post-transplant complications related to steroids?
Reactivation of BK virus, Femoral head AVN ## Footnote Immunosuppression increases the risk of these complications.
812
What associations are there with ureter calcifications?
TB and schistosomiasis
813
What is ureteritis cystica?
Tiny subepithelial cysts associated with diabetics and chronic inflammation
814
What is retroperitoneal fibrosis associated with?
IgG4 disorders (autoimmune pancreatitis) ## Footnote It presents as medial deviation/waisting of ureters.
815
True or False: Allergic reactions are a risk factor for contrast-induced nephropathy.
False ## Footnote Risk factors include renal insufficiency, diabetes, and CHF.
816
transplant complications in first week: MAG3 poor flow, delayed uptake, and slow excretion  MAG3 normal flow, normal uptake, delayed excretion in a month: MAG3 normal flow, normal uptake, delayed excretion MAG3 poor flow, delayed uptake, and slow excretion
elevated RIs Acute rejection: antibody mediated Acute tubular necrosis: ischemia during harvest Cyclosporin toxicity: nephrotoxic reaction Chronic rejection: T-cell mediated
817
Leukoplakia vs malakoplakia
Leukoplakia: chronic irritation-> squamous metaplasia (Premalignant for squamous cell) Malakoplakia: chronic irritation/UTIs (E coli), immunocompromised women (NOT premalignant)
818
AAST kidney trauma
Grade 1: subcapsular hematoma Grade 2: subcapsular hematoma and <1 cm laceration Grade 3: >1 cm laceration w/o involving renal pelvis; active bleed within perirenal space Grade 4: laceration into hilum (fracture); bleeding outside perirenal space; segmental infarcts related to vascular injury Grade 5: shattered kidney, urine leak or main vessel injury; devascularized kidney
819
renal transplant Vascular complications
Renal allograft compartment syndrome (Immediately): when kidney too larg Renal artery thrombosis (Within first moments): due to kinking/torsion of the vessel Renal vein thrombosis (Within first week): see reversal of diastolic flow in ARTERY Renal artery stenosis (Within first year): results in refractory hypertension, most common complication
820
what is diffuse nonperfusion, wedge shaped perfusion defect, and persistent nephrogram indiate in the setting of trauma
Diffuse nonperfusion: devascularized kidney Wedge shaped perfusion defect: segmental arterial injury Persistent nephrogram: renal vein injury/thrombosis
821
What is involved in urinary TCC?
Bladder > renal pelvis > ureter lower > upper ureter prostatic urethera ## Footnote where urine sits static the longest
822
Which substances are associated with TCC?
* Smoking * Arsenic * Aniline * Benzidine * Bladder diverticulum
823
What conditions are associated with bladder SCC? how does it apear
* Schistosomiasis * Suprapubic catheters * Leukoplakia Heavily calcified bladder and ureters
824
Where is urinary adenocarcinoma?
* Urachus * Bladder exstrophy * Urethral diverticulum
825
paratesticular mass in children
rhabdomyosarcoma
826
Grape-like polypoid mass ?
sarcoma botryoides variant of rhabdomyosarcoma
827
Pine cone shaped bladder?
neurogenic bladder
828
What type of cancer is typically found in the urethra?
Squamous cell carcinoma ## Footnote Transitional cell carcinoma may occur in the prostatic urethra, while adenocarcinoma is found in urethral diverticulum.
829
What type of cancer occurs in the bladder?
most commonly transitional cell (include bladder divert) squamous cell (schisto, suprapub catheter) adenocarcinoma (urachus, urethral diverticulum, extrophy)
830
turner syndrome is associated with
Aortic coarctation horseshoe kidneys streaky ovaries prepubertal uterus (tube-like shape, cervix and uterus same size)
831
what develops from the mullerian ducts
uterus, fallopian tubes, upper ⅔ vagina
832
what develops from the Urogenital sinus:
lower ⅓ vagina and prostate
833
what develops from the wolffian ducts
vas deferens, seminal vesicles, epididymis
834
hysterosalpingogram findings
-Tubal occlusion iso PID: dilated tubes w abrupt cutoff/obstruction and no spill of contrast -Salinities isthmica nodosa Nodular scarring of fallopian tubes -Ashermans (intrauterine adhesions): Irregular linear filling defects
835
What is the increased risk associated with hereditary non polyposis colon cancer (HNPCC)?
Increased risk of endometrial cancer ## Footnote HNPCC is also known as Lynch syndrome
836
thickened endometrium and ovarian lesion
Granulosa theca cell tumor of ovary or endometrial cancer w ovarian met ## Footnote Granulosa cell tumors are a type of sex-cord stromal tumor that can produce estrogen and affect the endometrial lining.
837
rapid enlargement of fibroid with necrosis
Malignant transformation of fibroid ## Footnote Leiomyosarcoma
838
What characterizes a peritoneal inclusion cyst?
Entraps ovary, lacks discrete walls, conforms to surrounding shape
839
What type of cancer is endometrial cancer classified as? Cervical cancer?
Adenocarcinoma Squamous cell (HPV)
840
What are the types of cancers associated with vaginal cancer?
* Squamous cell carcinoma (most common) * Clear cell carcinoma (associated with DES) * Rhabdomyosarcoma (in children)
841
simple paraovarian cyst next step
no follow up required, regardless of size
842
post menopausal ovary
should be less than 6 cc and cold on PET
843
premenopausal ovary next step
If <3 cm: normal follicle If >3 cm: get US-> if >7 cm needs 3 mo f/u
844
postmenopausal ovary next step
If <1 cm: normal cyst If >1 cm: get US-> if >5 cm needs 3 mo f/u If not simple, w septations, projections, solid elements-> Gyn
845
What type of ovarian tumor is described as unilocular with few septations, papillary projections, and ascites?
Serous ovarian cystadenocarcinoma/cystadenoma ## Footnote This is typically bilateral and malignant.
846
What type fo ovarian tumor is described as multiloculated with thin septations and low level echoes
mucinous ovarian cystadenocarcinoma
847
What condition is associated with postpartum pelvic pain and fever?
Ovarian vein thrombosis ## Footnote It typically presents as a tubular structure with an enhancing wall and low attenuation thrombus.
848
True or False: Serous ovarian cystadenocarcinoma is typically unilateral.
False ## Footnote It is described as bilateral.
849
increasing hcg following evacuation of mole
choriocarcinoma very vascular and bloody echogenic
850
prostate anatomy
fibromuscular zone (anterior) central zone (transitional gland and central gland) peripheral zone (adenocarcinoma)
851
early enhancement and washout cancers
prostate, breast and HCC
852
seminal vesicle cysts associated with
congenital: polycystic kidney disease, renal agenesis, vas deferens agenesis acquired: prostate hypertrophy or surgery
853
testicular artery flow in torsion and pitfall
Absence of arterial flow Monophasic arterial flow High resistance arterial flow with low or reversed diastolic flow note testicular artery NOT cremasteric artery
854
epididymitis spread and causes
Spreads tail to body to head Chlamydia/gonorrhea in younger E. coli from uti in older
855
orchitis causes
spread from epididymitis mumps
856
Age 18-35 w undescended testicle
seminoma
857
Age 18-35 w retro peritoneal adenopathy
testicular cancer
858
Multiple hypoechoic masses or enlarged hypoechoic testicle
lymphoma
859
how do testicular/ovarian cancers metastasize
through paraaortic and caval lymphatics except choriocarcinoma (hematogenous)
860
germ cell testicular tumor appearance
Seminoma (middle aged white male): Most common, best prognosis with radiation Homogenous T2 dark, hypoechoic Non seminoma (teenager): Heterogenous w calcs and cystic spaces
861
Causes of Infertility:
Pituitary adenoma (prolactin) Kallman syndrome (anosmia and infertility) Klinefelters (tall, gynecomastia, infertile) Zinner syndrome (renal agenesis and seminal vesicle cyst)
862
types of abortion:
Threatened (bleeding w closed cervix) Inevitable (dilated cervix w tissue hanging out) Incomplete (residual products in uterus) Complete (all products out) Missed (fetus dead but in uterus)
863
double bleb sign in pregnancy
Yolk sac and amniotic sac within the chorionic cavity
864
amniotic band syndrome
If amnion is disrupted before 14-16 weeks, fetus gets into chorionic cavity
865
prognostic factor most associated with fetal demise in subchorionic hemorrhage
percentage of placental detachment
866
pregnancy failure classified as
-CRL crown rump length >7 mm w/o heartbeat -MSD mean sac diameter >25 mm w/o embryo -No embryo or heartbeat ->2 weeks after US showing gestational sac w/o yolk sac ->11 days after US showing gestational sac w yolk sac
867
What indicates an empty uterus in the context of ectopic pregnancy?
-pregnancy/yolk sac out side of uterus -Empty uterus with anything on adnexa -empty uterus with moderate free fluid
868
What is the most common site for an ectopic pregnancy?
Fallopian tube ampulla
869
What is the tubal ring sign?
Echogenic ring specific for ectopic
870
Fetal growth parameters
Biparietal (outer edge of skull to inner table) Head circumference (not including skin) Abdominal circumference (not including soft tissues) Femur length (femoral shaft not including femoral epiphysis)
871
increase diastolic flow and decreased resistance of intrauterine MCA doppler
Abnormal brain sparing reflex Normal: high resistance waveform with continuous diastolic forward flow
872
Increased peak systolic flow of MCA intrauterine doppler
Fetal anemia--> hydrops enlarged liver and spleen Maternal immunization or parvovirus
873
what does elevated systolic/diastiolic ratio of umbilical artery indicate
high resistance =preeclampsia and IUGR
874
oligohydramnios causes
renal failure (cannot pee to make urine/amniotic fluid) placental insufficiency-> growth restriction
875
polyhydramnios causes
GI issue (cannot swallow amniotic fluid) gestational diabetes
876
one vessel visualized lateral to bladder
umbilical artery in two vessel cord
877
What is the significance of cystic rhombencephalon in the posterior fossa at 6-8 weeks?
It is normal.
878
What does midgut herniation at 9-11 weeks indicate?
Normal physiologic rotation.
879
What do echogenic foci in the ventricle indicate?
Papillary muscle calcification, which can be seen in Down syndrome.
880
What is a chorioangioma in the placenta and what are the imaging features?
A hamartoma of the placenta near the cord insertion. well circumscribed, hypoechoic with pulsating doppler flow which matches fetal heart rate
881
How is hydrops diagnosed?
By subcutaneous edema plus: pleural effusion, pericardial effusion, or ascites. secondary to rh sensitization, TORCHS can see increased peak systolic MCA flow
882
What does HELLP syndrome stand for and what is it associated with?
Hemolysis, elevated liver enzymes, low platelets DIC and subcapsular hematoma
883
In which syndromes is Twin oligohydramnios polyhydramnios sequence seen and not seen?
* Twin-twin transfusion syndrome * Twin reversed perfusion syndrome not seen: * Twin anemia polycythemia sequence * Twin embolization syndrome
884
what is the normal appearance of the adrenal gland
y shaped with triple stripe (oreo) appearance
885
discoid adrenal gland
congenital pancake shape in kidney agenesis
886
Horseshoe adrenal gland
associated with right isomerism/asplenia/trilobed lung
887
adrenal cyst next step
in adult: nothing (benign) in kid: resected (cannot distinguish from cystic neurblastoma)
888
what does adrenal hyperplasia look like and what can it be due to
enlarged and wrinkly with gyri/sulci (looks like brain) -congenital adrenal hyperplasia (genital ambiguity with testicular adrenal rests and salt loss) -cushing disease (excess ACTH and cortisol) -cushing syndrome (excess cortisol)
889
imaging features of pheochromocytoma on CT and pitfall
avid enhancement >120 HU regardless of washout, cannot be adrenal adenoma
890
what is pheochromocytoma associated with
VHL, MEN2a and MEN2b
891
what can adrenal calcifications represent?
infection, TB myelolipoma, neuroblastoma, cortical carcinoma
892
MEN1
parathyroid hyperplasia, pituitary adenoma (prolactinoma), pancreatic tumor (gastrinoma: zollinger ellison syndrome & duodenal ulcers)
893
MEN2A
parathyroid hyperplasia, pheochromocytoma, medullary thyroid cancer
894
MEN2B
pheochromocytoma, medullary thyroid cancer, neuromas (mucosal and intestinal), marfanoid
895
multiple paragangliomas (head and neck glomus tumors) is suggestive of
hereditary paraganglioma/pheochromocytoma syndrome
896
hallmark of papillary thyroid carcinoma
microcalcifications
897
thyroid nodules: Peripheral flow and hypoechoic halo Solid hypoechoic w central flow
-benign -suspicious
898
acute suppurative thyroiditis in kids spreads from
fourth branchial cleft anomaly
899
delphian node
level 6 nodule=laryngeal cancer met
900
central sulcus homunculus
omega sign corresponds to hand motor function ACA territory corresponds to leg
901
virchow robin spaces can be seen with
dilated perivascular spaces along basal ganglia -mucopolysaccharidoses (hunters and hurlers) -gelatinous pseudocysts (cryptococcal meningitis) -age
902
1) cavum septum pellucidum 2) cavum et vergae 3) cavum velum interpositum
903
basal cisterns
Suprasellar cistern: look like a star Interpeduncular cistern Sylvian cisterns (2) Ambient cisterns (2) Quadrigeminal plate cistern smile/moon
904
which cranial nerve is contained within a sleeve
CN3 within CSF sleeve/oculomotor cistern
905
order of the cranial nerves
oh oh oh to touch and feel very good velvet ah olfactary, optic, oculomotor, trochlear, trigeminal, abducens, facial, vestibulocochlear, glossopharyngeal, vagus, accessory spinal, hypoglossal
906
what travels in the optic canal
optic nerve (CN2) and ophthalmic artery
907
what travels in meckels cave
trigeminal ganglion
908
what travels in dorello's canal
abducens nerve (CN6)
909
branches of ECA
Some Administrators Love Fucking Over Poor Medical Students Superior thyroid; Ascending pharyngeal; Lingual; Facial; Occipital; Posterior auricular; Maxillary; Superficial temporal
910
what does middle meningeal artery arise from
off of maxillary artery from ECA
911
ECA vs ICA
external: anterior and high resistance internal: posterior and low resistance
912
what do the pericallosal and callosomarginal arteries originate from?
A2 segment of ACA
913
what does acute unilateral pupil dilation suggest
oculomotor CN3 palsy PCOM or basilar aneurysm
914
what does acute lateral rectus palsy suggest
abducens CN6 palsy increased ICP with inferior herniation stretches CN6
915
what is fetal origin of PCA And complication
PCA is fed by PCOM P1 segment is absent or diminutive Ipsilateral anterior and posterior stroke
916
superficial cerebral veins
vein of trolard and vein of labbe (inverse relationship) superficial middle cerebral vein
917
myelination pattern what is myelinated at birth and what is last to myelinate
-immature myelin (water): T1 dark and T2 bright -mature myelin: T1 bright and T2 dark -myelination occurs inferior to superior, posterior to anterior, central to peripheral -brainstem and posterior limb internal capsule at birth; subcortical white matter last
918
order of corpus callosum formation
genu->body->isthmus->splenium->rostrum
919
agenesis/dysgenesis of the corpus callosum is associated with
colpocephaly intracranial lipoma absent splenium
920
what is iniencephaly
NEURAL tube defect, at posterior cervical region/occipital bone with enlarged foramen magnum Star gazing fetus due to hyperextended contortion
921
Joubert syndrome
Molar tooth appearance of superior cerebellar peduncles Large fourth ventricle with absent/small vermis, small cerebellum Absent fastigial point and primary fissure
922
increased posterior fossa cystic space ddx
-dandy walker, chiari 2, Joubert syndrome -Blake pouch (Sac like cystic protrusion of fourth ventricle through foramen of magendie, sometimes w choroid projecting into pouch) -Mega cisterna magna (Focal enlargement of retrocerebellar CSF space)
923
lobar holoprosencephaly?
front/fornix is mildly fused Mild fusion frontal horns, incomplete septum, partial corpus callosum
924
semilobar holoprosencephaly?
front fused, back cleaved Body of lateral ventricles is 1 chamber cleft lip/palate Absent/partial septum, corpus callosum, anterior interhemispheric fissure, anterior falx cerebri
925
alobar holoprosencephaly?
zero midline cleavage Fused cerebral hemispheres and single midline mono ventricle Monster cyclops, single nostril, solitary mega incisor, pyriform aperture stenosis, do not survive Absent septum, corpus callosum, interhemispheric fissure, falx cerebri
926
What is hemimegalencephaly?
Enlargement/disproportionate growth of all parts of one cerebral hemisphere
927
What distinguishes hemimegalencephaly from Rasmussen's encephalitis?
Dilated ventricle and enlarged hemisphere vs large ventricle and small hemisphere (atrophy with ex vacuo dilation)
928
What is Dyke Davidoff Masson syndrome?
Similar to Rasmussen’s encephalitis but with unilateral skull thickening and expanded sinuses
929
Define lissencephaly type 1.
undermigration Reverse migration outside-in pattern: neurons deposit between ventricle/pial surfaces without cortical folding smooth surface and thick cortex colpocephaly figure 8 shape
930
What characterizes double cortex band heterotopia?
undermigration Disorganized migration results in second layer of cortical neurons deep to true cortex (double cortex appearance)
931
Define lissencephaly type 2.
overmigration Additional layer of cortex consisting of nodules, typically adjacent to sylvian fissures (cobblestoned cortex appearance) ## Footnote This type is associated with muscular dystrophy and retinal detachment.
932
What occurs in periventricular nodule heterotopia?
failed migration Neurons in periventricular region do not migrate and deposit along ventricle borders ## Footnote Grey matter nodules do not enhance, compared to subependymal tubers of tuberous sclerosis.
933
What is polymicrogyria?
Overfolding of superficial layers leading to fine undulating/bumpy cortex ## Footnote This condition can be associated with Zika virus, TORCH infections, and toxic exposure.
934
Describe schizencephaly.
Cleft lined with grey matter between ventricle and pia ## Footnote It can present as open lip (CSF filled cleft extending) or closed lip (no CSF filled cleft).
935
What is a porencephalic cyst?
Brain cleft from prior ischemic event leading to encephalomalacia ## Footnote This cyst is not lined by grey matter.
936
What causes hydranencephaly?
Bilateral ICA occlusion leading to destruction of bilateral hemispheres ## Footnote The cerebellum, midbrain, and falx remain intact in this condition.
937
Differentiate between meningocele and encephalocele.
Meningocele: meninges and csf, no brain Encephalocele: BRAIN, meninges, and csf
938
What is a cystocele?
VENTRICLE, brain, meninges, and csf
939
What is a myelocele?
A myelocele indicates a defect involving the spinal cord
940
What is Mesial temporal sclerosis characterized by?
Hippocampal volume loss with T2 bright gliosis/scar atrophy of ipsilateral fornix and maxillary body contralateral amygdala enlargement ## Footnote Results in seizures/epilepsy.
941
What are the features of Intracranial hypotension?
Meningeal engorgement/enhancement dural venous sinus distention intracranial vessel prominence engorgement of pituitary subdural hematoma/hygroma
942
What are the classic symptoms and appearance of Normal pressure hydrocephalus?
Wet, wacky, wobbly (urinary incontinence, ataxia, confusion) Ventricles out of proportion to atrophy, upward bowing of the corpus callosum.
943
What is Pontine osmotic demyelination?
overcorrection of low sodium levels slurred speech, labile emotional response T2 bright central pons w peripheral sparing diffusion restriction of pons
944
What does Thiamine B1 deficiency result in?
wenicke encephalopathy memory loss and confabulation/Korsakoff
945
What is Marchiafava Bignami characterized by?
T2 bright acute demyelination of the corpus callosum sandwich sign preference for central fibers on sagittal imaging Chronic phase demonstrates thinned corpus callosum with cystic genu and splenium cavities
946
What are the features of PRES (posterior reversible encephalopathy syndrome)?
Asymmetric cortical and subcortical white matter edema without diffusion restriction.
947
What are the early and late features of Post radiation changes on imaging?
Early: T2 flair signal in periventricular white matter Late: mosaic pattern with sparing of U-fibers and corpus callosum.
948
What criteria define Multiple sclerosis?
Separated in time and space perivascular pattern (periventricular and juxtacortical) involvement of the calloso-septal interface.
949
What does MR spectroscopy reveal in Multiple sclerosis plaques?
Reduced NAA peaks within the plaques.
950
What is a common appearance of active Multiple sclerosis plaques?
Restrict diffusion incomplete ring enhancing lesions.
951
Who and what does Subcortical arteriosclerotic encephalopathy (SAE) primarily affect?
Old people with hypertension White matter disease of centrum semiovale, spares cortical U-fibers.
952
What are the main features of Alzheimer’s dementia?
Amyloid cascade neurofibrillary tangle tauopathy Down syndrome
953
What imaging findings are associated with Alzheimer’s dementia?
Hippocampal and temporal atrophy low uptake in posterior temporoparietal region on FDG PET.
954
What characterizes Multiinfarct/vascular dementia?
Cortical and lacunar infarcts with brain atrophy scattered areas of decreased activity on FDG PET
955
What is Lewy body dementia?
alpha synuclein and synucleinopathy Visual hallucinations, spontaneous parkinsonism, fluctuating alertness.
956
What is the imaging finding in Lewy body dementia?
Decreased FDG uptake in lateral occipital cortex, sparing mid posterior cingulate gyrus (cingulate island sign)
957
What are the clinical features of Frontotemporal dementia/Picks?
Compulsive and inappropriate behaviors low FDG uptake in frontal and temporal lobes
958
Neurodegenerative disease with Extensive calcification of basal ganglia and thalami
Fahr disease
959
Upper motor neuron loss.
ALS
960
What imaging finding is characteristic of Huntington disease?
Caudate atrophy with convex enlarged frontal horns.
961
What does Leigh disease involve?
Mitochondrial disorder with T2 lesions in brainstem, basal ganglia, cerebral peduncles, periaqueductal gray.
962
What syndrome is MELAS ?
mitochondrial encephalomyopathy, lactic acidosis, seizures, strokes
963
What is the I123 DAT scan finding in Parkinson's disease?
loss of normal comma shape
964
Mickey mouse sign
PSP progressive supranuclear palsy tauopathy atrophy of tegmentum w sparing of tectum and peduncles
965
What characterizes Wilson disease and what appearance?
Copper accumulation, Kayser Fleischer rings on slit lamp. T1 bright basal ganglia, and panda sign (T2 bright tegmentum w normal red nuclei and substantia nigra)
966
What is the next step in adults with a solitary CNS mass?
Look for primary since likely to be metastasis.
967
Where are metastases most likely located in the brain?
At grey-white junction.
968
What does the PDOG mnemonic stand for in regards to cortically based masses?
Pleomorphic xanthoastrocytoma, Dysembryoplastic neuroepithelial tumor, Oligodendroglioma, Ganglioglioma.
969
What is the appearance of Pleomorphic xanthoastrocytoma (PXA)?
Cyst with enhancing nodule and dural tail in temporal lobe.
970
What is the imaging appearance of Dysembryoplastic neuroepithelial tumor (DNET)?
Bubbly T2 bright lesion with FLAIR rim in temporal lobe, no enhancement.
971
What is the characteristic of Oligodendroglioma?
Astrocytoma expanding the cortex in frontal lobe with ribbon calcifications.
972
What is the presentation of Desmoplastic infantile ganglioglioma?
Rapidly increasing head circumference < age 1, large cystic tumor involving cortex.
973
What imaging finding is Zuckerguss icing enhancement associated with?
drop metastases medulloblastoma Breast cancer
974
hummingbird sign
PSP progressive supranuclear palsy tauopathy midbrain volume loss w concave upper surface and sparing of pons
975
what is the characteristic of ganglioglioma
cystic and solid with focal calcifications in temporal lobe
976
rhabdoid tumor/atypical teratoma
infratentorial large heterogeneously enhancing mass w necrosis and calcs (vs medulloblastoma which is typically younger (age 2) and with calcs)
977
hypothalamic hamartoma at the tuber cinereum (between mammillary bodies and optic chiasm precocious puberty and gelastic seizures
978
MRI spectroscopy represents
Differences in resonance frequency choline: cell membrane turnover NAA: neuronal viability tumor with increased choline and decreased NAA necrosis with decreased choline meningioma with alanine
979
what is the most common TORCH infection and when are they the most harmful
CMV: periventricular calcifications and thin ependymal enhancement; microgyria most harmful in the second trimester
980
toxoplasmosis vs lymphoma
ring enhancing lesions toxo is thallium cold and does not restrict diffusion lymphoma is thallium hot and restricts diffusion
981
what does swirl sign indicate
active bleeding central hypodense hyper acute blood surrounded by hyperdense acute clotted blood
982
appearance of blood on MRI
IB, ID, BD, BB, DD (T1 and T2) hyperacute, acute, early subacute, late subacute, chronic
983
what situations can pseudo subarachnoid hemorrhage be seen?
iffuse cerebral edema and compression of subarachnoid spaces iso anoxic brain injury like near drowning or hanging
984
stroke enhancement timing and fogging
seen in 3 days, peaks at 3 weeks, resolves by 3 months fogging occurs 2-3 weeks post infarct when brain looks normal
985
what does aspect score apply to
acute MCA stroke only
986
MR perfusion for infarct core and penumbra
core: low CBV and CBF penumbra: high CBV and low CBF with high MTT
987
CNS lesions w calcifications
Old Elephants Age Gracefully Oligodendroglioma Ependymoma Astrocytoma Ganglioglioma
988
crescent sign intravascular
dissection represents T1 bright intramural hematoma
989
watershed territory infarct in kid
suggest Moya moya nonatherosclerotic stenosis puff of smoke on angiogram
990
anatomy of the ear
outer ear to tympanic membrane middle ear contains epitympanum, mesotympanum, and hypotympanum, with ossicles inner ear past round/oval windows, with vestibular apparatus and cochlea
991
facial nerve enhancement
bells palsy, Lyme Ramsay hunt
992
What skull lesion is characterized by a thickened and expanded skull in the sclerotic phase?
Pagets disease ## Footnote Involves both inner and outer tables of the skull.
993
What skull lesion presents as ground glass appearance?
Fibrous dysplasia in individuals younger than 30 ## Footnote Favors the inner table of the skull.
994
What is the primary arterial source for posterior epistaxis? and next step
Sphenopalatine artery-> embolization ## Footnote Terminal branch of the internal maxillary artery.
995
What ducts are associated with sialolithiasis?
Wharton's duct in submandibular Stenson's canal in parotid gland
996
What is the characteristic appearance of a keratogenic odontogenic tumor?
Multilocular keratocyst without cortical expansion ## Footnote Associated with Gorlin syndrome.
997
What type of tumor is an ameloblastoma?
Locally aggressive multicystic tumor of the mandible
998
What is sunburst pattern in the mandible?
osteosarcoma
999
What condition is linked to osteonecrosis of the mandible?
Prior radiation, licking radium paint brush, or bisphosphonate treatment
1000
What structures are found in the parotid space?
Parotid gland, CN7 facial nerve, retromandibular vein
1001
What is found in the carotid space?
carotid artery, jugular vein, CN9, 10, 11, lymph nodes Paraganglioma, schwannoma, neurofibroma
1002
What is the most common mass found in the masticator space?
Odontogenic infection otherwise masticator muscles
1003
What condition presents with diffusely enlarged parotid glands and bilateral mixed solid/cystic lesions?
Benign lymphoepithelial disease
1004
What is the difference between schwannoma and neurofibroma?
Schwannoma: cystic & solid, hyperenhancing; NF2 Neurofibroma: T2 target sign (bright rim, dark middle); NF1 ## Footnote Schwannoma is associated with NF2, while neurofibroma is associated with NF1.
1005
What can cause necrotic cervical lymph nodes? necrotic lymph nodes with calcifications
Squamous cell carcinoma in adults can be infectious in kids thyroid carcinoma
1006
Hoarseness with expanded ventricle on ipsilateral side
vocal cord paralysis if on left, think recurrent laryngeal nerve
1007
What is Coats disease characterized by?
unilateral small globe WITHOUT CALCIFICATION Retinal telangiectasia leading to retinal detachment in young boys
1008
What are the symptoms of metastatic neuroblastoma?
Periorbital tumor infiltration with bilateral proptosis-> raccoon eyes involvement of sphenoid wing
1009
What is the Graves thyroid orbitopathy? and order of involvement
painless and spares myotendinous insertion, with enlargement of muscle belly IMSLO: inferior, middle, superior, lateral, oblique
1010
What is tolosa hunt syndrome
IgG4 disease involving the cavernous sinus -painful, multiple cranial nerve palsies
1011
What separates the preseptal and postseptal space in the orbit? Intraconal vs extraconal?
Orbital septum Preseptal infections: from adjacent structures, treated medically; Postseptal infections: from paranasal sinusitis, treated surgically Intraconal: space inside rectus muscle pyramid; extraconal: outside
1012
What does optic nerve enhancement indicate if the nerve is enlarged? or isn't enlarged?
Glioma (NF1) optic neuritis (devic disease)
1013
What is a Schmorls node?
Herniation of disc material into vertebral body endplate
1014
What is the defining characteristic of Brown-Sequard syndrome?
Hemi motor deficit and contralateral hemi sensory deficit
1015
swollen and increased T2 of cord with serpentine flow voids along surface of cord?
Dural AVF
1016
What does bilateral symmetric increased T2 of dorsal columns indicate?
HIV myelopathy or vitamin B12 deficiency (subacute combined degeneration)
1017
Extramedullary intradural lesion with central necrosis or hemorrhage
Schwannoma Solitary, dumbbell appearance t1 dark t2 bright, enhancing does not envelop nerve root
1018
What is the significance of the aortic isthmus?
It is the segment of the aorta between the left subclavian and ligamentum arteriosum most common area of traumatic pseudoaneurysm
1019
What is the anatomical significance of the ductus bump?
Contour bulge just distal to the isthmus, a normal structure
1020
What branches does the superior mesenteric artery (SMA) give off?
Inferior pancreaticoduodenal, middle colic, right colic, ileocolic, appendicular
1021
What condition results in multiple wedged vertebral bodies leading to kyphosis in teens?
Scheuermann's disease multilevel with associated schmorl's nodes
1022
What distinguishes a herniation from a disc bulge?
Herniation: >25% displacement; Disc bulge: <25% displacement
1023
What is the typical imaging appearance of a vertebral hemangioma?
T1 dark, T2 bright
1024
What is a limbus vertebra?
Result of herniated disc material between unfused apophysis and vertebral body (mimics fracture)
1025
What is the classic appearance of a neurofibroma on imaging?
T2 bright rim and central low signal, often enveloping the nerve root
1026
skull lesions
-Pagets: thickened expanded skull in sclerotic phase involving inner and outer table -Fibrous dysplasia: ground glass in younger than 30, favors inner table
1027
what are Enthesioneuroblastomas and what do they appear as
olfactory cells with dumbbell shape from waisting at cribiform plate Homogenous enhancement neural crest cells, octreotide positive
1028
nasal epistaxis next step
-anterior: involves kiesselbach plexus, -posterio:r involves sphenopalatine (terminal internal maxillary artery) artery-> embolization
1029
sialolithiasis locations
submandibular= Whartons duct parotid= stenson canal
1030
Odontogenic infection is more common in what scenario?
in extracted teeth vs intact tooth with abscess ## Footnote More common than in intact teeth with abscess.
1031
Where do infections from anterior mandibular teeth spread? Where do infections from mandibular molars spread?
Sublingual space (ABOVE mylohyoid muscle) Submandibular space (BELOW mylohyoid muscle) ## Footnote Above the mylohyoid muscle.
1032
What is a periapical cyst?
Odontogenic cyst at apex of tooth with border.
1033
What is a dentigerous or follicular cyst?
Cyst around crown of unerupted tooth.
1034
Extramedullary intradural lesion with T2 bright rim and central low signal
neurofibroma (target sign) -solitary or plexiform (bulky multilevel nerve enlargement pathognomonic for NF1) envelops nerve root
1035
IMA branches?
left colic, sigmoid branches, superior rectal
1036
arc of riolan
connects left colic from ima to middle colic on sma
1037
where do ovarian arteries arise from
anteromedial aorta and anastomose w uterine artery from internal iliac anterior branch
1038
Periventricular Cystic changes in newborn=
periventricular leukomalacia
1039
T1 dark bone marrow=
fatty marrow replacement= leukemia
1040
t2 bright and enhancing nidus in posterior elements of spine
osteoid osteoma/osteoblastoma
1041
”onion bulb” nerve roots with diffuse thickening
Chronic inflammatory demyelinating polyneuropathy (CIDP) w protracted weakness
1042
orbital cystic structure which distends with valsalva
-orbital varix: weakness in venous wall; most common cause of spontaneous hemorrhage -orbital lymphangioma: does NOT distend; venous and lymphatic malformation; infiltrative, multispatial (septal/conal), fluid fluid levels;
1043
carotid cavernous fistula and types
-pulsatile exophthalmos -direct: secondary to trauma -indirect: post menopausal women
1044
dacrocryocystitis
inflammation of lacrimal sac medially (NOT the gland laterally); well circumscribed rim enhancing lesion
1045
drusen
calcification/mineralization of optic disc
1046
focal discontinuity of globe
coloboma; failure of choroid fissure to close
1047
normal conus medullar is terminates at
Conus medullaris terminates around L1; think tethered cord if below L2/L3
1048
osteophytes vs syndesmophytes
-osteophytes: horizontal/claw like/oblique (in DJD & spondylosis) -syndesmophytes: thin, vertical, symmetric ossification of the annulus fibrosus (in ankylosing spondylitis with fusion of facets)
1049
ossification of the anterior longitudinal ligament w/o significant disc disease
DISH
1050
disc impingment on spinal nerves
-foraminal disc will impact the exiting nerve at that level -subarticular/central disc will impact the descending nerve exiting below that level
1051
LP/myelogram indications:
-advanced degen spondylosis, post surgical changes, fat, mri contraindication -don’t need to hold aspirin/nsaids
1052
LP/myelogram contraindications
-increased ICP or obstructed CSF flow, bleeding, contrast allergy
1053
increased distance of lateral masses on odontoid view
Jefferson fracture (axial loading on C1)
1054
Orthotopic vs dystopic dens:
orthotopic ossicle is located at odontoid tip while dystopic ossicle is fused to clivus
1055
anterior arch-dens distance > 5mm
Atlantoaxial instability: associated with down syndrome and juvenile RA
1056
vessel through strait sign=
vessel in ligamentum venosum fissure (likely replaced or accessory left hepatic artery) replaced left hepatic artery from left gastric artery
1057
Collateral pathways:
Celiac-> common hepatic-> GDA-> superior pancreaticoduodenal-> inferior PDA-> SMA Arc of riolan: SMA-> middle colic-> arc of riolan-> left colic-> IMA IMA-> superior rectal-> inferior rectal-> internal pudendal-> anterior division internal iliac
1058
marginal artery of drummond
along inner border of colon; terminal branches of SMA’s ileocolic, right and middle colic, and IMA’s left colic and sigmoid branches form continuous arterial circle (always present)
1059
parapharyngeal space contains and is affected by:
ball of fat with branches of trigeminal nerve -parotid mass pushes it medially -carotid mass pushes it anteriorly -mucosal mass pushes it laterally -masticator space mass pushes it posteromedially
1060
enhancing T1 bright mass in back of eye, “collar button shaped”
Melanoma: -most common intraocular lesion in adult -next step liver MRI for mets
1061
disc herniation types and classification
-protrusion: wider base than herniated disc -extrusion: neck narrower than herniated disc -sequestration: broken off disc fragment
1062
post op spinal surgery enhancing lesion in operative bed
-recurrent/residual disc: DOES NOT enhance -epidural fibrosis: scar enhances homogeneously
1063
what is the anterior cord vs posterior cord responsible for
Anterior cord: motor function and pain/temperature sensation Posterior cord: proprioception and vibration Anterior cord syndrome from flexion injuries can lead to immediate paralysis
1064
Demyelinating disease in the cord imaging characteristics
-MS: most common; short segment lesion with partial cord involvement -transverse myelitis: long segment, involving full transverse diameter of cord with swelling -NMO: long segment, involving full transverse diameter of cord with swelling; NMO IgG attacks periventricular aquaporin 4 channels -ADEM: post viral kid or YA, favor dorsal white matter, with brain lesions
1065
thoracic outlet triangle of nerves and vessels Thoracic outlet syndrome:
Anterior scalene, middle scalene, and first rib form triangle containing: -subclavian artery and brachial plexus -subclavian vein runs anterior to triangle compression of subclavian vessels through thoracic inlet, typically by anterior scalene muscle
1066
Upper extremity artery anatomy
subclavian artery-> axillary artery (at the first rib)-> brachial artery (at the inferior border of the teres MAJOR)-> ulnar and radial at the radial head
1067
what supplies the superficial palmar arch
ulnar larger and gives off the common interosseous artery radial supplies the deep arch
1068
lower extremity artery anatomy
External iliac artery-> common femoral (after giving off inferior epigastric)->deep and superficial femoral artery->popliteal-> anterior tibialis and tibioperoneal trunk-> peroneal and posterior tibialis
1069
arteries at the ankle
-anterior tibialis traverses interosseous membrane and terminates as dorsalis pedis -posterior tibialis is most medial artery, felt at medial malleolus
1070
What is the response level for conscious/moderate sedation?
Should respond briskly to verbal commands or light touch ## Footnote This indicates the level of sedation where the patient is still able to interact and respond appropriately.
1071
What is the reversal agent for Versed/midazolam? for opioids?
Flumazenil Narcan ## Footnote Flumazenil is used to reverse the effects of benzodiazepines like midazolam.
1072
What is a contraindication for IVC filter placement?
Total IVC thrombosis
1073
What are the contraindications for fistulography?
Right to left shunt, uncorrectable coagulopathy, fistula infection ## Footnote These conditions increase the risk of complications during the procedure.
1074
What are the contraindications for TIPS?
Right heart failure, severe encephalopathy, severely progressing liver failure ## Footnote These conditions indicate that the risks of the TIPS procedure outweigh the potential benefits.
1075
Which procedures are contraindicated with uncorrectable coagulopathy?
Fistulography, percutaneous transhepatic cholangiography, percutaneous nephrostomy NOT a contraindication to percutaneous biliary drainage/cholecystostomy ## Footnote Uncorrectable coagulopathy increases the risk of bleeding during these procedures.
1076
What do duplicated SVC and IVC drain into what is duplicated IVC associated with
SVC into coronary sinus IVC into left renal vein horseshoe kidney and cross fused renal ectopic
1077
what is significance of circumaortic renal collar
accessory left renal vein passes posterior to aorta
1078
heterotaxy:
right isomerism: asplenia, trilobed right lung, horseshoe adrenal left isomerism: polysplenia,
1079
Azygos continuation of IVC
absence of hepatic segment of IVC, azygos continues inferiorly to abdomen
1080
what determines Type A vs Type B dissection
based on relative position to left subclavian takeoff
1081
-saccular morphology above diaphragm= -saccular morphology below diaphragm=
penetrating ulcer septic/mycotic aneurysm from hematogenous seeding with saccular morphology
1082
penetrating ulcer vs dissection
penetrating ulcer: atheromatous plaque erodes through intima and forms hematoma in media dissection: hypertension results in intimal tear
1083
which lumen is true vs false in dissection which contains left renal artery
-false lumen: larger than true lumen; contains origin of left renal artery
1084
static dissection vs dynamic dissection
-static dissection flap: extends into feeding artery (treat by stenting) -dynamic dissection flap: dangles in front of artery (treat by fenestration)
1085
pseudoaneurysm demonstrates what kind of flow at the neck
to and fro
1086
Impending rupture: draped aorta sign and hyperdense crescent sign
1087
what can cause pulmonary artery aneurysm
swan ganz catheter, behcets, chronic PE, TB (called rasmussens aneurysm)
1088
tulip bulb annuloaortic ectasia
Marfan aortic valve insufficiency
1089
Loeys dietz syndrome
hypertelorism (frog eyes), bifid uvula or cleft palate, tortuous arteries (aortic rupture, vertebral arteries)
1090
what is inflammatory aneurysm associated with
young men, elevated ESR, smoking, associated with hydronephrosis or renal failure
1091
figure 3 sign on CXR
aortic coarctation
1092
pseudocoarctation
narrowing and kinking of aorta without pressure gradient, collaterals, or rib notching
1093
chronic mesenteric ischemia
food fear, crampy pain after eating; most common affects splenic flexture
1094
acute mesenteric ischemia
Arterial clot/thrombus: thin bowel wall without dilation Venous mesenteric ischemia: dilated bowel w wall thickening, fat stranding/ascites
1095
nutcracker syndrome
SMA compresses renal vein, affects gonadal vein vs SMA syndrome which compresses the duodenum
1096
renal artery narrowing causes and differences
Renal artery stenosis: atherosclerosis, narrowing at the ostium; medical treatment or can stent Fibromuscular dysplasia (FMD): stricturing and beading of artery; young white women, sparing ostium, NOT related to atherosclerosis Do not stent, can angioplasty
1097
serpiginous structures in myometrium next step
uterine AVM-> needs embolization can be acquired or congenital
1098
painful bloody diarrhea, intussusception, massive skin edema overlying scrotum in child
henoch schonlein Purpura
1099
Churg strauss:
necrotizing vasculitis eosinophilic lung disease and asthma eosinophilia + transient peripheral lung consolidation/ground glass
1100
strawberry tongue, rash of palms and soles, sore throat in children
Kawasaki
1101
carotid artery doppler with stenosis
prestenosis: decreased peak systolic velocity and diastolic flow stenosis: increased peak systolic velocity poststenosis: tarsus parvus
1102
what does parvus tardus waveform in the unilateral carotid artery mean what about the bilateral carotid arteries
upstream innominate stenosis aortic stenosis
1103
what does reversal of diastolic flow in the bilateral carotid arteries mean what about loss of diastolic flow
aortic regurgitation brain death
1104
measuring catheter sizes gauge and french
-Gauge: bigger number=smaller size -French: bigger number=bigger size; -3 French=1 mm -add 2 French to inner diameter for outer diameter
1105
What is designated by outer diameter: What is designated by inner lumen diameter:
-needles, wires, catheter, dilator -sheaths
1106
IR instrument package labeling
outer diameter (Fr), length (cm), inner diameter (in)
1107
what size guidewires can an 18G and 19G needle accept? 21G micropuncture?
0.038 and 0.035 in (fits in 4 Fr catheter) 0.018 in
1108
IR vessel flow rates
1-2 ml/s: bronchial artery, intercostal artery 4-8 ml/s: carotid, subclavian, IMA, renal, femoral, celiac, SMA 20-30 ml/s: aorta, arch, pulmonary artery, IVC
1109
pseudoanuerysm treatment tree
compression <2 cm thrombin (>2 cm) surgery (if thrombin fails, there is tissue breakdown/infection, or aneurysm neck too wide)
1110
if you tilt II toward head and needle gets longer: if you tilt II toward head and needle gets shorter: if you tilt II toward feet and needle gets longer: if you til II toward feet and needle gets shorter:
-deep -superficial -superficial -deep
1111
IR fluoro II positioning based on target
-typically ipsilateral to what you want to see, ie aorta-> LAO -iliac bifurcation is exception-> contralateral oblique (left iliac bifurcation-> RAO)
1112
fibroid treatment based on location
Submucosal: do the best with UAE Intracavitary: hysteroscopic resection Subserosal fibroid-> myomectomy Cervical: do not respond to UAE bc different blood supply
1113
types of stents and their uses
-self expandable stents for superficial locations that get compressed -balloon expandable for precise deployment -closed cell stent: every segment is connected; more radial force -open cell stent: some segments are open; less radial force, more flexible
1114
if trying to cross tight stenosis and see spiral of wire
dissection
1115
endovascular stenting vs open repair
Endovascular repair: less 30 day mortality but higher graft complications and reintervention same long term aneurysm related mortality
1116
stent/graft patency staging
Primary patency: patency of original graft without additional intervention Assisted primary patency: patency maintained by prophylactic measures/interventions Secondary patency: patency is lost but restored by second intervention
1117
what is contraindicated in varicose vein treatment
DVT bc need superficial veins
1118
antegrade vs retrograde access
based on direction of flow antegrade is further in flow direction retrograde is backwards in flow direction
1119
indications for IVC filter placement
-pts with DVT but contraindication to anticoagulation -pts on anticoagulation with known PE
1120
pulmonary collection IR intervention
drain pleural empyema do NOT drain lung abscess (risk of bronchopleural fistula)
1121
What is intimal hyperplasia?
Healing response to blood vessel wall damage leading to restenosis ## Footnote Intimal hyperplasia is a common response after vascular injury that can lead to narrowing of the vessel.
1122
What is Polyarteritis nodosa (PAN) associated with?
Men and hep B; renal, cardiac, and GI artery microaneurysms-> infarction (wedge-shaped renal infarct)
1123
What are the primary organs affected by Microscopic polyangiitis?
Kidney and lung, leading to pulmonary hemorrhage
1124
What is the biggest risk factor for infectious aortitis?
Atherosclerosis, seeding of plaques
1125
What is Subclavian steal syndrome?
Proximal left subclavian stenosis causing reversal of vertebral artery flow to distal subclavian ## Footnote Early steal waveform looks like a rabbit.
1126
Where is the intraaortic balloon pump typically placed?
Distal to left subclavian and proximal to renal arteries
1127
When does the intraaortic balloon pump inflate?
In early diastole, right after aortic valve closes, to displace maximum blood available (assisted peak on doppler)
1128
What is the function of a Left Ventricular Assist Device (LVAD)? and what does doppler look like?
Pumps blood from left ventricle to aorta Mostly flat, almost tardus parvus
1129
What is a recurved catheter?
A catheter with primary and secondary curves in opposite directions
1130
What is a curved catheter?
A catheter with primary and secondary curves in the same direction
1131
What test is performed before radial access?
Allen test
1132
Is bedrest required after radial access compression?
No
1133
What is the protocol if there is an infection at the access site?
No closure device should be used
1134
What is primary stenting?
Angioplasty first, stent after to prevent recoil
1135
What is the purpose of anticoagulation after stenting?
To avoid thrombosis after intimal injury ## Footnote Usually involves aspirin or clopidogrel for 1-3 months.
1136
What do drug-eluting stents do?
Retard intimal hyperplasia
1137
What are particulate agents used in embolization?
Gelfoams, blood clot, PVA particles (permanent)
1138
What are mechanical agents used in embolization?
Coil, amplatzer vascular plug
1139
Why should coils not be used for bronchial artery embolization?
They block reaccess and should not be used for things that may rebleed
1140
What should be checked before IVC placement?
angiogram run prior to IVC placement to assess IVC patent status, size, duplication, renal vein position
1141
Where is the IVC typically placed?
Infrarenal unless contraindicated by pregnancy (avoid compression), renal/gonadal vein clot, duplicated IVC (bilateral filter or suprarenal)
1142
What is a contraindication to access for fistulogram?
Infection
1143
What is the access method for a fistulogram?
Access the venous side (anterograde) and obstruct venous outflow to visualized the arterial side
1144
What is the direction to access the right portal vein during TIPS?
Turn anterior when in the right hepatic vein
1145
What is Balloon occluded retrograde transverse obliteration (BRTO)?
Scleroses gastric varices through gastrorenal shunt, driving blood into the liver
1146
How does BRTO differ from TIPS?
BRTO can worsen esophageal varices and ascites but improve hepatic encephalopathy; TIPS diverts blood around the liver; treats esophageal varices and ascites, but can result in worsening encephalopathy
1147
What is the normal biliary ductal anatomy?
Left hepatic duct (horizontal; supplies lobes 2 & 3) Right hepatic duct-> splits into anterior (vertical; supplies lobes 5 & 8) and posterior (horizontal; supplies lobes 6 & 7)
1148
What is Chilaiditi syndrome?
Bowel in front of liver, a relative contraindication for PTBD
1149
What should be done if a patient experiences rigors after injection for PTBD?
Evaluate for cholangitis
1150
When is a transjugular liver biopsy indicated?
Significant ascites, uncorrectable coagulopathy, and thrombocytopenia
1151
how to biopsy a peripheral or subcapsular liver mass
through normal liver tissue
1152
What does mild shoulder pain post-liver biopsy indicate?
normal but if prolonged >5 min may suggest Kehr sign bleeding; evaluate with ultrasound
1153
What is TACE and its complications?
trans arterial chemoembolization with hepatic arterial lipiodol High risk of biliary abscess sterile/chemical cholecystitis: when lipiodol is injected into the hepatic artery before the cystic artery takeoff
1154
What are the differences between Microwave and Radio Frequency Ablation?
Microwave is for bigger lesions, less ablation time, less affected by heat sink, does not need grounding pad
1155
How does Cryoablation work?
Thawing kills cancer cells, not the freezing
1156
What is the most common source of upper GI bleed?
Left gastric artery may be prophylactically embolized if no bleed is visualized
1157
What is a Dieulafoy's lesion?
Large subdural stomach artery which tears the wall and bleeds
1158
What should be avoided during lung biopsy?
Crossing fissures; lower lungs affected by respiratory motion
1159
What is a risk associated with UAE?
DVT/PE
1160
What is post-embolization syndrome?
Low grade fever <3 days after procedure
1161
What characterizes pelvic congestion syndrome?
Dilated ovarian and periuterine veins
1162
What does aspirin do?
Binds irreversibly to platelets
1163
How is heparin monitored?
By PTT and reversed by protamine sulfate
1164
How is Coumadin/warfarin monitored?
By INR and reversed by vitamin K or immediately by cryoprecipitate
1165
What are the pre-IR procedure requirements?
Correct INR <1.5, platelets >50,000, hold plavix/clopidogrel 5 days, no hold on aspirin
1166
the shrinking breast
sign of invasive lobular carcinoma
1167
steps of localizing breast lesions
On MLO draw line through lesion paralleling posterior nipple line; On frontal clockface draw line parallel to and above or below PNL (oriented from upper inner through nipple to lower outer) On CC view determine if medial or lateral and peripheral or central
1168
rolled breast view is performed how
Rolled view direction refers to top of breast superior lesions move in direction of rolling inferior lesions move the opposite direction
1169
BIRADS classification for screening mammo
-BIRADS 0: needs additional imaging (suspicious finding or technical issue) -BIRADS 1: negative -BIRADS 2: benign findings (cysts, lipoma, galactoceles, hamartoma, multiple well circumscribed similar BILATERAL masses, or unchanged previously worked up lesion)
1170
BIRADS classification for diagnostic mammo
-BIRADS 2: work up is benign -BIRADS 3: 2 year follow up, <2% chance of malignancy -BIRADS 4: 2-95% chance of malignancy, could be benign -BIRADS 5: >95% chance of malignancy, cannot accept benign result -BIRADS 6: biopsy proven cancer
1171
Anterior mediastinal mass in kids Posterior mediastinal mass in kids
-lymphoma -neuroblastoma
1172
what descriptors are used for mammogram masses? for ultrasound masses?
-shape, margin, density -shape, margin, orientation, echo pattern, posterior features
1173
what descriptors are used for mass margins on mammogram? on ultrasound?
(COMIS): circumscribed, obscured, microlobulated, indistinct, spiculated (CAMIS): circumscribed, angular, microlobulated, indistinct, spiculated
1174
what do egg-shell calcifications indicate? if large? if multiple?
-oil cyst/fat necrosis -macrocystica liponecrosis -steatocystoma multiplex
1175
what do damaged RBC vs tagged RBCs target
-spleen -heart (blood/bleeding and hemangioma)
1176
Gallium 67 vs indium 111 WBC scan differences
-Indium better at evaluating intraabdominal abscess -Gallium better at evaluating spine (osteo) and lungs
1177
Tc99m WBC vs Indium 111 WBC
-Tech 99m WBC: visualize renals and GI -Indium 111 WBC: localize to spleen
1178
HMPAO vs Indium 111 WBC
-HMPAO better at evaluating inflammatory bowel, children, and extremity osteomyelitis -In WBC better at evaluating fever of unknown origin
1179
Inflammatory breast cancer/peau de orange:
presents as hot swollen red breast -skin thickening without focal palpable mass -may improve but does not resolve with antibiotics (vs mastitis) -chemo/radiation prior to surgery
1180
high risk breast lesions:
-radial scar (complex sclerosing lesion): dense fibrosis around ducts w appearance of dark scar -atypical ductal hyperplasia: DCIS but <2 ducts involved-> excised -atypical lobular hyperplasia: excised -lobular carcinoma in situ: occult on mammogram -papilloma: intraductal mass lesion in subareolar region; causes bloody discharge; duct dilation on US
1181
most suspicious breast discharge? non suspicious discharge?
-spontaneous bloody discharge from single duct: suspicious for papilloma or DCIS -non milky non bloody discharge: fibrocystic change or ductal ectasia
1182
describe characteristics of invasive ductal carcinoma on physical exam and MG
-physical exam: hard, non mobile, painless mass -MG: high density irregular w spiculated or indistinct margins, w pleomorphic calcs
1183
Multifocal breast cancer vs Multicentric breast cancer:
-multiple primaries in same quadrant -multiple primaries in different quadrants
1184
cardiac MRI first pass perfusion vs delayed gadolinium enhancement
Microvascular obstruction: first pass perfusion Ischemia: delayed enhancement
1185
T1 bright lesion of ventricle wall on cardiac MRI
Arrhythmogenic right ventricular dysplasia fat within ventricle
1186
cardiac MRI infarct appearance
Acute MI: T2 bright edema Chronic MI: T2 dark fibrous scar
1187
pericardial and pleural effusions
Lupus
1188
what kind of pulmonary association do Scleroderma and Sjogren's have
NSIP dilated esophagus LIP (ground glass and cysts)
1189
mediastinal lesions
Normal thymus: homogeneous without mass effect Lymphoma: mass effect with SVC compression and lymph nodes Teratoma: calcs, fat, cystic Seminoma: lobulated bulky midline lesion Non seminoma germ cell tumor: necrosis and hemorrhage
1190
mammoplasty and mastoplexy
-swirled appearance of inferior breast related to keyhole incision -mammoplasty: reduce breast size -mastopexy: removal of skin
1191
breast cancer staging
-T1-3 based on size -T4 if invades chest wall, skin, or is inflammatory breast carcinoma (BC) -T4 excludes paget disease skin changes
1192
breast cyst vs mass on US-> what steps
try to aspirate lesion-> -if non bloody and lesion disappears-> toss fluid -if bloody and lesion disappears-> cytology -if purulent and lesion disappears-> microbiology culture -if fluid and lesion does NOT disappear-> core biopsy solid mass
1193
what is the Mammography quality standards act (MQSA) and who governs it
under FDA -recall rate should be less than 10% -required consumer complaint mechanism in mammo facilities -interpreting physician is responsible for quality control -phantom dose should be less than 3 mGy per image
1194
What is injected in lymphangiography?
ethiodol To opacify lymph vessels and nodes ## Footnote Ethiodol is a contrast agent used in imaging studies.
1195
What is the structure of the breast anatomy at the level of the ducts?
Terminal duct lobular unit -> lobules -> major duct -> lactiferous sinus ## Footnote This pathway is crucial for understanding breast milk production and drainage.
1196
Where do most breast cancers originate?
In the TDLU and upper outer quadrant ## Footnote This information is critical for screening and diagnostic imaging.
1197
What imaging modality is most sensitive in lactating patients?
Ultrasound ## Footnote Ultrasound can better visualize breast tissue changes during lactation.
1198
What is a risk associated with biopsy of a lactating breast?
Risk of milk fistula ## Footnote Milk fistula can complicate healing and require further management.
1199
In MLO view, what happens to medial and lateral lesions on true lateral imaging?
Medial lesions rise and lateral lesions sink ## Footnote This principle is important for accurate interpretation of mammographic images.
1200
What is MRI background parenchymal enhancement identified on?
Based on first post-contrast sequence ## Footnote This enhancement pattern can aid in differentiating between benign and malignant lesions.
1201
What are dermal calcifications indicative of?
Benign; stay in same place on both views ## Footnote Tangential views can help confirm their benign nature.
1202
What is Pseudoangiomatous stromal hyperplasia (PASH)?
Benign myofibroblastic hyperplastic process with big solid oval, well-defined borders ## Footnote PASH can mimic malignancy but is not cancerous.
1203
What is Paget's disease of the breast associated with?
DCIS; carcinoma in situ of nipple ## Footnote Skin changes and palpation findings are critical for diagnosis.
1204
What is the purpose of pulmonary artery banding?
To treat CHF or single ventricle iso pulmonary overcirculation due to left to right shunt ## Footnote This procedure manages blood flow and pressure in congenital heart defects.
1205
What are the three types of arterial switch procedures?
Jatene, Senning, Mustard ## Footnote These procedures are used for transposition of the great arteries.
1206
What does the Fontan procedure do?
Bypasses SVC to pulmonary artery ## Footnote This procedure is associated with specific cardiac conditions.
1207
What is the association of right-sided total anomalous pulmonary venous return?
Associated with ASD sinus venosis ## Footnote Understanding this association aids in diagnosis and management.
1208
What does signal dropout on in and out of phase imaging indicate?
Microscopic fat ## Footnote This finding can be relevant in characterizing certain lesions.
1209
List causes of terminal ileitis.
* Tuberculosis * Crohn's * Ulcerative colitis * Yersinia ## Footnote Differential diagnosis is essential for appropriate treatment.
1210
When should a lymph node be biopsied?
If thick cortex, loss of central fatty hilum, irregular margins ## Footnote These features suggest malignancy or significant pathology.
1211
What does gold therapy indicate in lymph nodes?
Dense calcifications within lymph node ## Footnote This is a characteristic finding in certain conditions.
1212
What are the key imaging findings in DIP?
* Apical emphysema * Basilar ground glass * Peripheral basilar reticulation ## Footnote These findings are associated with smoking and RB-ILD.
1213
What are the characteristics of LAM?
Thin wall cysts, even distribution ## Footnote LAM is often associated with tuberous sclerosis.
1214
What is the imaging pattern of eosinophilic pneumonia?
Reverse edema pattern peripherally with ground glass and consolidation ## Footnote This pattern helps differentiate it from other forms of pneumonia.
1215
What is the difference between male breast anatomy and female breast anatomy?
Male breast does not have ducts or lobules ## Footnote This difference influences the pathology that can occur in males.
1216
What is nodular gynecomastia?
Physiologic enlargement of epithelial & stromal elements, centered behind nipple ## Footnote It often presents with radiation.
1217
What are the types of implant placement locations?
* Subglandular/retromammary * Subpectoral/retropectoral ## Footnote Each placement has implications for imaging and complications.
1218
How can saline implant rupture be detected?
Can be seen on mammogram ## Footnote This is important for monitoring implant integrity.
1219
What characterizes silicone implant rupture?
Forms capsule around implant; extra or intra rupture ## Footnote Extracapsular rupture shows “snow storm” on ultrasound.
1220
What are contraindications to breast-conserving therapy (BCT)?
* Inflammatory cancer * Large cancer size * Multicentric cancer * Prior radiation therapy or contraindication to radiation therapy ## Footnote These factors influence treatment decisions.
1221
What is the local recurrence rate of cancer with BCT therapy? local recurrence w/o radiation?
6-8% 35% ## Footnote Without radiation, the local recurrence rate is 35%.
1222
Close margins of mass/calcs to edge of tissue in breast cancer excision?
concerning for incomplete excision ## Footnote This raises the suspicion of incomplete excision.
1223
skin thickening and trabecular thickening post radiation?
expected findings unless gets worse over time, c/f recurrent disease or inflammatory BC ## Footnote If these changes worsen over time, it may indicate recurrent disease.
1224
What is secondary angiosarcoma after radiation therapy?
Presents as red plaques or skin nodules with skin thickening (T2 bright) ## Footnote This condition can develop years after radiation treatment.
1225
What is the most important predictor of survival in breast cancer?
Axillary status ## Footnote This factor significantly influences prognosis.
1226
What are the most common metastases to the breast?
* Lymphoma * Melanoma ## Footnote Recognizing these can aid in diagnosis and treatment planning.
1227
What is the most significant on MRI breast?
Suspicious morphology trumps kinetics (spiculated=80% malignancy) ## Footnote This principle helps in assessing breast lesions.
1228
What does the MRI breast enhancement curve look like?
Initial upslope (slow, medium, rapid) followed by secondary curve (continued rise, plateau, or rapid washout) ## Footnote Different curves indicate varying levels of malignancy risk.
1229
Which washout curve has the highest cancer risk?
Rapid washout curve ## Footnote This finding necessitates further investigation.
1230
What factors increase the risk of breast cancer related to estrogen exposure?
* Early menarche * Late menopause * Late pregnancy * No pregnancy * Fat * Alcohol * Hormone replacement ## Footnote Screening recommendations may apply to transgender women.
1231
What is the imaging recommendation for bilateral or unilateral cyclical breast pain?
No imaging is appropriate ## Footnote Cyclical pain is common and typically benign.
1232
What should be done for noncyclical breast pain?
Ultrasound ## Footnote This helps evaluate potential underlying issues.
1233
What is the imaging recommendation for newly diagnosed stage 1 breast cancer?
No imaging is appropriate ## Footnote Initial management focuses on treatment rather than further imaging.
1234
What is the imaging recommendation for gynecomastia/pseudogynecomastia?
No imaging is appropriate ## Footnote Imaging is not routinely needed unless there is suspicion of cancer.
1235
If there is concern for cancer in a male with gynecomastia, what imaging should be performed?
Always get mammogram in addition to ultrasound ## Footnote Gynecomastia can mimic cancer on ultrasound.
1236
What is the imaging recommendation for indeterminate breast palpation in patients under 25?
Ultrasound ## Footnote Younger patients typically require less invasive evaluation.
1237
What is the imaging recommendation for indeterminate breast palpation in patients over 25?
Mammogram; if indeterminate, ultrasound ## Footnote This age group requires more thorough investigation.
1238
What is the next step of breast palp with mammogram findings of lipoma?
No ultrasound, no further imaging is appropriate ## Footnote Lipomas are generally benign and do not require additional imaging.
1239
What is the procedure for stereotactic biopsy?
Performed in compression; if breast compresses too small <20 mm, place wire localization for excisional biopsy ## Footnote This prevents negative stroke margin issues.
1240
What are the requirements to read a mammogram?
* Formal 3 months training * 60 hrs of education * Read 240 studies in last 2 years ## Footnote These standards ensure competency in mammogram interpretation.
1241
What must be provided to the patient after reading a mammogram?
Lay summary of mammogram within 30 days ## Footnote This is part of patient communication and care.
1242
What are the daily QA requirements for mammography?
* Processor QC * Darkroom cleanliness ## Footnote These checks are essential for maintaining imaging quality.
1243
What are the weekly QA requirements for mammography?
* Viewbox conditions * Phantom evaluation ## Footnote Regular assessments help ensure accurate imaging results.
1244
What are the quarterly QA requirements for mammography?
Repeat analysis ## Footnote This helps identify any long-term trends in imaging quality.
1245
What are the semiannual QA requirements for mammography?
* Compression test * Dark room fog * Screen film contrast ## Footnote These evaluations are crucial for patient safety and image clarity.
1246
What is Wilms tumor characterized by?
Solid tumor, acquired; grows like solid ball, invades vessels ## Footnote It is one of the most common kidney tumors in children.
1247
presents with * Renal cysts and masses * Pancreatic cysts and masses * Adrenal masses
von hippel lindau ## Footnote This genetic disorder has multiple tumor associations.
1248
presents with * Renal cysts * AML * Lung cysts
tuberous sclerosis ## Footnote Tuberous sclerosis is a genetic disorder that affects multiple organ systems.
1249
presents with * Small calcified spleen * Bone infarcts * Gallstones
sickle cell ## Footnote These findings can arise from vaso-occlusive crises.
1250
presents with * Large spleen and liver * Extramedullary hematopoiesis * Bone infarcts
gaucher ## Footnote Gaucher disease is a lysosomal storage disorder.
1251
prsents with * Fatty pancreatic atrophy * Small bowel stool * Fatty liver
cystic fibrosis ## Footnote These findings are due to pancreatic insufficiency.
1252
presentation of * Renal and adrenal masses * Skin nodules * Scoliosis
neurofibromatosis type 1 (NF1) ## Footnote NF1 is a genetic disorder characterized by skin and nervous system tumors.
1253
presentation of * Liver vascular malformation * Bowel angiodysplasia * Lung AVM * Brain abscess
hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu) ## Footnote This condition leads to abnormal blood vessel formation and bleeding risks.
1254
tagged rbc scan with focal activity in liver
hemangioma
1255
granular opacities and low lung volumes
surfactant deficient disease GBS pneumonia both in premies but GBS pneumonia with pleural effusion
1256
cystic bubbly lucencies
PIE (with pneumothorax) bronchopulmonary dysplasia both related to ventilator but BPD/CLD is chronic 3-4 weeks postnatal
1257
ropy appearance with hyperinflation
meconium aspiration post mature babies
1258
transient tachypnea of the newborn
coarse interstitial markings and fluid in fissures c section birth or maternal sedation
1259
pulmonary hamartoma
macroscopic fat in pulm nodule sometimes with dystrophic calcs no further follow up required
1260
age of solid kidney tumors
from birth: mesoblastic nephroma and nephroblastomatosis age 4: wills teenager: RCC and lymphoma
1261
when should transplant be considered for HCC
patients <65 yo with limited tumor burden
1262
anatomy of cerebellum
1263
elastofibroma dorsi
1264
column of bertin
1265
Paget disease associated with mickey mouse sign
1266
what disease and associations?
cleidocranial dysostosis complete or segmental absence of clavicles, wormian bones, and deficiency/absence of the pubic bodies
1267
what is coarctation associated with
bicuspid aortic valve (50-85%), posterior ductus arteriosus (66%), ventricular septal defect (33%), transposition of the great vessels, and Turner syndrome
1268
Testicular microlithiasis is associated with
germ cell tumor
1269
well defined cortical based metaphyseal lesion
NOF/fibrous cortical defect benign do not touch vertical orientation with thin rim
1270
Lipomatous hypertrophy of the interatrial septum (LHIAS): high signal T1 common incidental finding on imaging require no further work-up in an asymptomatic patient with a normal sinus rhythm
1271
epiphyseal/apophyseal lesion in child
chondroblastoma, LCH, aneurysmal bone cyst, or infection
1272
germinal matrix hemorrhages
1) subependymal only 2) ventricular extension 3) ventricular enlargement 4) intraparenchymal hemorrhage
1273
hamstring attachment site
1274
what sign does this indicate what does the patient present with
"signet ring sign"  of cystic bronchiectasis, in which the "ring" represents the dilated airway Chronic productive cough
1275
anterior to posterior: lingual tonsils palatine tonsils adenoids
1276
pes anserine bursitis
1277