Deck 13 Flashcards

1
Q

What is a haptoglobin?

A

A substance that reduces oxidative damage associated with haemolysis by binding free haemoglobin. It also has bacteriostatic and immunomodulatory effects.

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2
Q

Cytokines that play an important role in the development of chronic inflammatory response are:

A

IL-1
TNF-a
IL-6
IL-12
IL-4
IL-10
TGF-b

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3
Q

Somatic hypermutation is:

A

a cellular mechanism by which the immune system adapts to the new foreign elements that confront it, as seen during class switching

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4
Q

The result of somatic hypermutation is:

A

B cells that emerge gets a stronger and more specific response to the antigen (affinity maturation), by enhancing the diversity of their BCR repertoire

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5
Q

When cytokines react to cells close to them this is an example of:

A

paracrine action

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6
Q
A
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