Deck 5

Question 1

Antigenicity means the ability of a substance:

Answer 1

To bind specific antibodies

Question 2

Antibodies in defence against extracellular pathogens are NOT required for:

Answer 2

direct killing of invaders

Question 3

By skin test in cattle with bovine tuberculin is tested the presence of:

Answer 3

Memory Th1 lymphocytes specific for mycobacterium bovis

Question 4

Ileal Peyer’s patches is for:

Answer 4

development of mature B cells in Ru, dogs and swine

Question 5

Spleen is for:

Answer 5

blood filtration and trapping of antigen from blood

Question 6

Thymus is for:

Answer 6

development of mature T cells

Question 7

IL-1 is produced by macrophages and acts on the hypothalamus to induce fever. This is an example of:

Answer 7

endocrine action

Question 8

Anti-inflammatory action of corticosteroids is given by inhibition of:

Answer 8

phospholipase A
NF-kB

Question 9

Superantigens:

Answer 9

Non-specifically bind to MHC class II molecule on antigen presenting cells and to TCR on T helper cells
Cause non-specific activation of T-cells, resulting in polyclonal T cell activation and massive cytokine production

Question 10

The anaphylatoxic effect has:

Answer 10

C5a and C3a

Question 11

Killing of virus by NK cells is or is not an antiviral mechanism used by the immune system?

Answer 11

Is NOT

Question 12

Antiviral mechanisms used by the immune system include:

Answer 12

IFN activation of virus-infected cells
Lysis of virus by complement
Lysis of virus-infected cells by complement

Question 13

The primary purpose of the adaptive immune system is to:

Answer 13

Protect from disease upon re-infection with a specific pathogen

Question 14

Coombs test is used for the diagnostic of disease caused by hypersensitivity:

Answer 14

type II

Question 15

Positive selection of T-lymphocytes ensures that the T-lymphocytes recognise:

Answer 15

Self-MHC molecules survive

Question 16

Immunoglobulin class switching is a biological mechanism that:

Answer 16

Changes a B-cell production of antibodies from one class to another

Question 17

NK cells are activated after:

Answer 17

Binding of ligand to KAR receptors in the abscence of activated KIR receptors

Question 18

Toxoid vaccines contain chemically modified:

Answer 18

bacterial toxins (products)

Question 19

Signalling to a cytotoxic T cell that a cell is infected with virus depends on:

Answer 19

binding of processed antigen to cell class I MHC

Question 20

To make a recombinant vaccine to a virus, the virus DNA is expressed:

Answer 20

In an avirulent vector, which may be a virus or a bacterium