Flashcards in deck_1423963 Deck (10):
What are huge two main mechanisms to maintain plasma osmolarity?
Sensation of thirstADH secretion
Where does tend majority of water reabsorption take place?
Proximal convoluted tubule
What are thee effects of ADH on the body?
Increase Aquaporin expressionIncreases ion reabsorption in the ascending limb of the loop of henlé by having a positive effect on the NKCC2Increases urea absorption
Where is ADH produced and stored?
Synthesised in the hypothalamus Stored in the posterior pituitary
What hormones are secreted from the anterior pituitary?
What hormones are secreted from the posterior pituitary?
Where are there receptors that detect changes in plasma osmolarity?
Osmoreceptors found in the hypothalamusSpecifically the Organum Vasculoum of the Laminae Terminalis (OVLT)
Which of the physiological mechanisms is the first to be activated and why?
ADH secretion as it is more sensitive to changes in plasma osmolarity -- sensitive to changes of 1%. Thirst is only activated when you are ~10% dehydrated
What is a hallmark of the ascending limb of the loop of henlé?
It draws ions out of the nephron and is known as the diluting segment