Definitions

Question 1

Chemotaxis

Answer 1

phenomenon in which somatic cells/bacteria/single cell organisms direct movements according to certain chemicals in the environment

Question 2

Antigen

Answer 2

Any substance that can elicit a specific immune response

Question 3

Epitope

Answer 3

A specific sequence of a protein or a carbohydrate recognised by the receptor molecule of the immune system

Question 4

Allogenic

Answer 4

Genetically different although belonging to or obtained from the same species

Question 5

Isotype

Answer 5

in all members of a species

Question 6

Xenogenic

Answer 6

Derived from or obtained from as organism of a different species

Question 7

Allotype

Answer 7

genetic variation between individuals

Question 8

Idiotype

Answer 8

variation in the variable domain of Ig especially the hypervariable region

Question 9

Fc

Answer 9

Fragent crystallisable region

Question 10

Fab

Answer 10

Fragment antigen binding

Question 11

Affinity

Answer 11

Strength of bond

Question 12

Avidity

Answer 12

Strength of interaction (depends on the combined affinity of each binding site)

Question 13

Polyclonal Immune Response

Answer 13

Multiple cell clones expand having recognised differnet, sometimes overlapping epitopes on the same antigen

Question 14

Oligoclonal Immune Response

Answer 14

A limited number of cell clones expand (often due to a prolonged immune process (eg prolonged inflammation)

Question 15

Monoclonal Proliferation

Answer 15

Usually represents malignant transformation of a single clone of B cells at some point in the process of differentiation