Definitions 6 Flashcards
What is colostrum?
The first secretion from the mammary glands after giving birth; rich in antibodies.
What is the secretory component of a cell?
Component of immunoglobulin A.
Proteolytic cleavage product of the polymeric immunoglobulin receptor which remains associated with dimeric IgA in seromucus secretions.
What is a PIg receptor?
Polymeric Immunoglobulin Receptor
Transmembrane protein; Fc receptor which facilitates the transcytosis of the soluble polymeric isoforms of IgA and IgM and immune complexes.
What is the J chain?
The protein component that links monomers of antibodies IgA and IgM to form polymeric antibodies capable of secretion.
What is an M cell?
Specialized epithelial cells that are primarily found overlying GALT lymphoid follicles such as the Peyer’s patches in the ileum.
Actively transport luminal antigens to the underlying lymphoid follicles to initiate an immune response.
What is precipitate?
The formation of insoluble complexes as a result of the specific interactions between antigen molecules and the corresponding antibody molecules, both in aqueous solution.
What is a substrate?
A molecule that an enzyme interacts with.
What is a conjugate?
The process of attaching an antigen to a larger molecule that will ensure that the antigen will activate an immune response that produces antibodies.
What is immunochromatography?
Lateral flow test; combines separation of the sample molecules and reagents based on migration on a solid support by capillary flow.
What is a single radial diffusion assay?
A quantitative immunodiffusion technique used to detect the concentration of antigen by measuring the diameter of the precipitin ring formed by the interaction of the antigen and antibody at optimal concentration.
What is an enzyme-linked immunosorbant assay (ELISA)?
The assay is a solid-phase type of enzyme immunoassay to detect the presence of a ligand in a liquid sample using antibodies directed against the protein to be measured.
