Derm Flashcards

(55 cards)

1
Q

erythema multiforme looks like

A

target lesions with erythema

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2
Q

erythema multiforme associated with

A

HSV
drug eruptions
mycoplasma pneumoniae

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3
Q

herpangina

A

virus causing painful mouth blisters
common in kids
coxsackie & echovirus
resolves itself

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4
Q

orf

A

parapoxvirus
caused by handling infected sheep
firm, fleshy nodule on hand commonly that can be red/blue
-> pustule -> crust over
cllears itself in 3-6weeks

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5
Q

Primary syphilis infection

A

chancre (painless ulcer)
local non-tender lymphadenopathy

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6
Q

secondary syphilis infection

A

systemic symptoms: fevers, lymphadenopathy
rash on trunk, palms and soles
buccal ‘snail track’ ulcers (30%)
condylomata lata (painless, warty lesions on the genitalia )

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7
Q

tertiary syphilis infection

A

gummas (granulomatous lesions of the skin and bones)
ascending aortic aneurysms
general paralysis of the insane
tabes dorsalis
Argyll-Robertson pupil

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8
Q

Investigations for syphilis

A

bloods
swab chancre for PCR

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9
Q

treponoma pallidum

A

syphilis

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10
Q

borrelia burgdorferi

A

lyme disease

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11
Q

early + late signs lyme disease

A

early: erythema migrans
late: heart block, nerve palsies, arthritis

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12
Q

necrotising fasciitis types

A

type 1 is caused by mixed anaerobes and aerobes (often occurs post-surgery in diabetics). This is the most common type
type 2 is caused by Streptococcus pyogenes

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13
Q

tuberous sclerosis non-derm signs

A

epilepsy

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14
Q

tuberous sclerosis tumours

A

periungal fibromas
facial angiofibromas
hamartomas aka angiomyolipomas
bone cysts

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15
Q

tuberous sclerosis skin

A

ash-leaf macules
shagreen patches

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16
Q

erythema infectiosum

A

slapped cheek, parvovirus b19

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17
Q

investigation for parvovirus b19

A

antibody test for parvovirus b19 IgM

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18
Q

NF1 tumours & skin

A

cafe-au-lait macuels
neurofibromas
azillary or inguinal freckling
optic glioma
lisch nodules

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19
Q

NF1 non-derm sign

A

learning difficulty

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19
Q

superficial melanoma site

A

trunk and limbs

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20
Q

acral/mucosal lentiginous melanoma site

A

acral: soles of feet, hands and nailbeds

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21
Q

lentigo maligna melanoma sites

A

sun damaged face/scalp/neck

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22
Q

nodular melanoma sites

A

anywhere but often trunk

23
Q

most common sites for melanoma mets

A

lung
brain
liver

24
melanoma types from most common to least
superficial spreading nodular lentigno maligna acral
25
major criteria melanoma
change in size change in shape change in colour
26
Secondary features (minor criteria) melanoma
Secondary features (minor criteria) Diameter >= 7mm Inflammation Oozing or bleeding Altered sensation
27
margins for excision if breslow thickness 0-1mm thick
1cm
28
margins for excision if breslow thickness 1-2mm thick
1-2cm
29
margins for excision if breslow thickness 2-4mm thick
2-3cm
30
margins for excision if breslow thickness >4mm thick
3cm
31
5 year melanoma survival if breslow thickness < 0.75 mm
95-100%
32
5 year melanoma survival if breslow thickness >4mm
50%
33
BCC what skin layer
keratinocytes in basal layer of epidermis
34
SCC what skin layer
keratinocytes in suprabasal layers
35
keratoacanthama looks like and may be confused with
looks like fast growing papule with keratin plug may be confused with SCC
36
Bowen's disease
RED SCALY patches often 10-15 mm in size slow-growing often occur on sun-exposed areas such as the head (e.g. temples) and neck, lower limbs
37
Actinic keratosis
small, CRUSTY or scaly, lesions may be pink, red, brown or the same colour as the skin typically on sun-exposed areas e.g. temples of head multiple lesions may be present
38
SCC excision margins
if <20mm - excision margin 4mm If >20mm - excision margin 6mm
39
rodent ulcers
BCC
40
Scabies treatment
permethrin 5% is first-line malathion 0.5% is second-line everyone in household do full body TWICE, 7 days apart
41
pompholyx
hands and feet worse in sweaty and hot small blisters very itchy management: emollients and topical steroids
42
Dermatitis in acral, peri-orificial and perianal distribution
→ ?zinc deficiency
43
SCC poorer prognosis if
diameter >20mm and depth >4mm
44
high-risk patients and in cosmetically important sites treatment for scc?
Mohs
45
SCC in situ AKA
Bowen's disease
46
SCC in situ AKA
Bowen's disease
47
Positive non-treponemal test + positive treponemal test consistent with active syphilis infection
consistent with active syphilis infection
48
Positive non-treponemal test + negative treponemal test
consistent with a false-positive syphilis result e.g. due to pregnancy or SLE
49
Negative non-treponemal test + positive treponemal test
consistent with successfully treated syphilis
50
RPR and VDRL are what type of syphilis tests
non-treponemal
51
Syphilis management
IM Benzathine penicillin OR doxy if pen allergic then monitor non-treponemal levels: should decrease 4fold
52
Fournier's gangrene
nec fasc of the perineum
53
which DM drug is most associated with fourniers gangrene
SGLT2 i
54
pain, swelling, erythema at the affected site often presents as rapidly worsening cellulitis with pain out of keeping with physical features extremely tender over infected tissue with hypoaesthesia to light touch skin necrosis and crepitus/gas gangrene are late signs
necrotising fasciitis