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Flashcards in Dermatological Deck (20):
1

Clark level I

Confined to epidermis

2

Clark level II

Invasion of papillary dermis

3

Clark level III

Filling of papillary dermis but not extending into reticular dermis

4

Clark level IV

Invasion of reticular dermis

5

Clark level V

Invasion of deep subcutaneous tissue

6

Breslow's depth I

≥0.75 mm

7

Breslow's depth II

0.76-1.5 mm

8

Breslow's depth III

1.51-2.25 mm

9

Breslow's depth IV

2.26-3 mm

10

Breslow's depth V

>3 mm

11

Basal cell carcinoma appearance

-Pearly white papule/plaque
-Overlying telangiectasiae
-Central ulceration
-Raised, rolled border

12

Management of basal cell carcinoma

-Electrodessication and curettage
-Cryotherapy
-Topical therapy (e.g. fluorouracil)
-Full thickness excisional biopsy
-Mohs surgery

13

Modified BRE grading

Tubule formation
Nuclear pleomorphism
Mitotic count

14

Types of melanoma

-Superficial spreading (on women's legs and men's torsos, age 30-50)
-Nodular
-Lentigo maligna (on sun-damaged face, elderly)
-Acral lentignous (on palmar/plantar skin, in darker people)

15

Squamous cell carcinoma appearance

-Red papule/plaque
-May become nodular with warty surface
-Central necrosis and sloughing to become ulcer
-Bleeding

16

Immunopathology of pemphigus vulgaris

Anti-desmosome IgG antibodies (between keratinocytes)

17

Immunopathology of bullous pemphigoid

Anti-hemidesmosome IgG antibodies (between epidermis and dermis)

18

Clinical features of pemphigus vulgaris

-Superficial, painful lesions
-Mouth erosions
-Epistaxis
-Dysphagia/odynophagia
-Conjunctivitis
-Nikolsky's sign

19

Clinical features of bullous pemphigoid

Deeper, pruritic lesions

20

Breast cancer screening

-Women aged 50-74 invited for mammogram every 2 years
-Women aged 40-49 and 75+ can also participate